Evaluation of the diagnostic role of transvaginal ultrasound measurements of endometrial thickness to detect endometrial malignancy in asymptomatic postmenopausal women

2016 ◽  
Vol 294 (2) ◽  
pp. 311-316 ◽  
Author(s):  
Cenk Yasa ◽  
Ozlem Dural ◽  
Ercan Bastu ◽  
Funda Gungor Ugurlucan ◽  
Aslı Nehir ◽  
...  
Keyword(s):  
Postmenopausal Women ◽  
Endometrial Thickness ◽  
Transvaginal Ultrasound ◽  
Ultrasound Measurements ◽  
Diagnostic Role

scholarly journals The diagnostic role of the β-hCG discriminatory zone combined with the endometrial pattern for ectopic pregnancy in Chinese women

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Qi Lu ◽  
Yiwei Wang ◽  
Xiao Sun ◽  
Yuhong Li ◽  
Jing Wang ◽  
...  
Keyword(s):  
Ectopic Pregnancy ◽  
Chinese Women ◽  
Endometrial Thickness ◽  
Transvaginal Ultrasound ◽  
Diagnostic Value ◽  
Wide Range ◽  
Endometrial Pattern ◽  
Diagnostic Role ◽  
Β Hcg

Abstract Previous studies have regarded the discriminatory serum β-hCG zone (DSZ) as a valuable tool for the diagnosis of ectopic pregnancy (EP). However, the wide range of the DSZ makes achieving a clinical diagnosis of EP difficult, and these reports do not indicate whether the DSZ is suitable for an EP diagnosis in Chinese women. Several studies have indicated that the endometrial pattern in patients with EPs is different from that in patients with intrauterine pregnancies (IUPs). The aims of this study were to define the DSZ cutoff value for Chinese women, test whether the endometrial pattern is a suitable predictor for EP, and assess the diagnostic value of these indicators. We enrolled participants with IUPs or EPs with abdominal pain and/or vaginal bleeding, and serum β-hCG level measurements and transvaginal ultrasound (TVS) were performed to assess the diagnostic value of the indicators for EP. The sensitivity and specificity for identifying an EP were improved by combining the DSZ, endometrial thickness and trilaminar pattern indexes. The results of this study might be helpful toward providing further options for the diagnosis of EP, especially for patients without hemoperitoneum or colporrhagia.

A Clinico-pathological Study of Transvaginal Endometrial Thickness Measurement in Asymptomatic Postmenopausal Patients and Patients with Postmenopausal Bleeding

2019 ◽  
pp. 1
Author(s):  
Ayse Filiz Gokmen Karasu ◽  
Seda Ates ◽  
Tugba Gurbuz ◽  
Nurhan Sahin ◽  
Taha Takmaz ◽  
...  
Keyword(s):  
Endometrial Thickness ◽  
Transvaginal Ultrasound ◽  
Thickness Measurement ◽  
University Hospital ◽  
Postmenopausal Bleeding ◽  
Pathological Study ◽  
Endometrial Polyps ◽  
Endometrial Sampling ◽  
Proliferative Endometrium

<p><strong>Objective:</strong> We aimed to determine the frequency of endometrial pathologies of patients who presented to our outpatient clinic with postmenopausal bleeding (PMB) and asymptomatic menopausal patients with a finding of thickened endometrium on transvaginal ultrasonography.</p><p><strong>Study Design:</strong> This study was performed at Bezmialem University Hospital. Women who presented to our clinic from January 2015 to January 2017 were analyzed. Patients were divided to two groups. All patients underwent transvaginal ultrasound with a 7.5 MHz probe. Endometrial sampling was performed by either blind D&amp;C (dilatation &amp; curettage) or pipelle sampling. We excluded patient specimens that were obtained by hysteroscopy.</p><p><strong>Results:</strong> Electronic records of a total of 368 patients in menopause were inspected. Out of these patients; 287 (78%) underwent endometrium sampling indicated by bleeding. Eighty-one patients (22%) were asymptomatic; however, a thickened endometrium echo on TVUSG examination (≥ 5 mm) was suspected. The median age was 57 (42-85). In both groups the two leading causes of endometrial pathology was; endometrial polyps followed by proliferative endometrium. The frequency of endometrial cancer was 9.4 % for the PMB group and 1.2 % in the asymptomatic patient group</p><p><strong>Conclusion:</strong> Evaluation of PMB as soon as possible is essential for diagnosing endometrial pathologies. Role of endometrial thickness is decisive in detecting patients at high risk for malignancy especially with comorbid conditions. Histopathological evaluation is mandatory for ruling out malignancy.</p>

91180913 The role of vaginal scan in measurement of endometrial thickness in postmenopausal women

Maturitas ◽  
1991 ◽  
Vol 14 (1) ◽  
pp. 85
Author(s):  
M.N. Nasri ◽  
J.H. Shepherd ◽  
M.E. Setchell ◽  
D.G. Lowe ◽  
T. Chard
Keyword(s):  
Postmenopausal Women ◽  
Endometrial Thickness

The role of vaginal scan in measurement of endometrial thickness in postmenopausal women

1992 ◽  
Vol 38 (1) ◽  
pp. 74-74
Author(s):  
MN Nasri ◽  
JH Shepherd ◽  
ME Setchell ◽  
DG Lowe ◽  
T Chard
Keyword(s):  
Postmenopausal Women ◽  
Endometrial Thickness

scholarly journals Ultrasound detection of endometrial fluid in postmenopausal women

2009 ◽  
Vol 62 (7-8) ◽  
pp. 337-341 ◽  
Author(s):  
Aleksandar Curcic ◽  
Srdjan Djurdjevic ◽  
Slobodana Mihaldzic-Tubic ◽  
Ljiljana Mladenovic-Segedi ◽  
Marko Maksimovic
Keyword(s):  
Postmenopausal Women ◽  
Endometrial Thickness ◽  
Transvaginal Ultrasound ◽  
Fluid Collection ◽  
Uterine Bleeding ◽  
Pathological Changes ◽  
Asymptomatic Group ◽  
Ultrasound Investigation ◽  
Asymptomatic Women ◽  
Histopathological Investigation

Introduction. The aim of this prospective study was to estimate whether the presence of endometrial fluid detected by transvaginal ultrasound investigation was a marker for the pathological changes of the endometrium in postmenopausal women. Material and methods. 128 postmenopausal women with uterine bleeding and 29 asymptomatic postmenopausal women underwent transvaginal ultrasound investigation, curettage and histopathological investigation of the curettage specimens. Results. There were significantly more asymptomatic women with endometrial fluid collection was found (41,4%) than those with uterine bleeding (7,8%) (p<0,001). We found 4 cases of carcinoma of the endometrium, 4 with hyperplasia and 1 with polyp of the endometrium in women with uterine bleeding and endometrial fluid collection. In the asymptomatic group of women we found 1 case with polyp and 1 with carcinoma of the endometrium. In the presence of endometrial fluid collection the least thickness of the endometrium measured by transvaginal ultrasound was 12 mm in postmenopausal women with carcinoma of the endometrium, 7 mm in women with hyperplasia and 5 mm with polyp. No pathological changes were found below the above values. Conclusion. The presence of endometrial fluid detected by transvaginal ultrasonography is a good marker for pathological changes of the endometrium in postmenopausal women if the endometrial thickness is greater than 4 mm. If the endometrial thickness is 4 mm or less, the presence of endometrial fluid is not an indication for further invasive investigation of endometrial cavity, but we must eliminate possible presence of ednexal or cervical malignant disease in some patients.

scholarly journals Synergistic approach in diagnosing endometrial disease in women with postmenopausal bleeding

2017 ◽  
Vol 6 (9) ◽  
pp. 4081
Author(s):  
Jiten Sharma ◽  
Bhishan Dhiman ◽  
Nishi Sud ◽  
Anupriya Kaushik
Keyword(s):  
Endometrial Carcinoma ◽  
Postmenopausal Women ◽  
Histopathological Examination ◽  
Endometrial Thickness ◽  
Transvaginal Ultrasound ◽  
Uterine Bleeding ◽  
Postmenopausal Bleeding ◽  
Endometrial Sampling ◽  
Combined Use ◽  
Vaginal Ultrasonography

Background: All women with postmenopausal uterine bleeding mandate examination for endometrial diseases especially endometrial carcinoma. In current scenario, hysteroscopy has replaced traditional Dilatation and Curettage as diagnostic procedure of choice. However, office endometrial sampling with pipelle combined with vaginal ultrasonography being easier and less expensive is recommended. Aim and objectives of the study was to evaluate the combined use of vaginal ultrasonography and office endometrial sampling for the diagnosis of endometrial disease in postmenopausal women with uterine bleeding.Methods: One hundred consecutive postmenopausal women presenting with uterine bleeding were enrolled in the study. Vaginal ultrasonography was used to measure the endometrial thickness. Endometrial sampling was done using endometrial biopsy pipelle, as office procedure, in the OPD examination room. The sample was sent for Histopathological Examination (HPE), The accuracy of vaginal ultrasound and pipelle was measured.Results: In 21% patients, endometrial carcinoma was found, endometrial hyperplasia in 26%, atrophic endometrium in 18%, endometrial polyp in 10% and no specific pathology in 20%. Endometrial thickness measured by Transvaginal ultrasound ranged from 1mm to 28mm with mean of 10.16mm and median of 11.5mm. The mean endometrial thickness in subgroup without disease was 5.26±3.8mm, with benign disease 12.8±3.1mm and in carcinoma 16.97±5.6mm. All cases with carcinoma had endometrial thickness exceeding 5mm (range 5.7mm to 28mm).Conclusions: The study illustrates that by combined use of Trans Vaginal Sonography (TVS) and office endometrial sampling, sufficient diagnostic information was obtained for women with postmenopausal bleeding, obviating the need for more invasive diagnostic procedures.

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