Termination of pregnancy following prenatally diagnosed central nervous system malformations

2018 ◽  
Vol 298 (5) ◽  
pp. 903-910 ◽  
Author(s):  
Christian M. Domröse ◽  
Sandra Bremer ◽  
Caroline Buczek ◽  
Annegret Geipel ◽  
Christoph Berg ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Termination Of Pregnancy

scholarly journals OP16.09: Termination of pregnancy for central nervous system (CNS) anomalies

2012 ◽  
Vol 40 (S1) ◽  
pp. 104-104
Author(s):  
W. Dendas ◽  
B. De Keersmaecker ◽  
P. Moerman ◽  
F. Claus ◽  
N. El Handouni ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Termination Of Pregnancy ◽  
Cns Anomalies

scholarly journals OC06.05: Termination of pregnancy for central nervous system (CNS) anomalies

2017 ◽  
Vol 50 ◽  
pp. 12-12
Author(s):  
W. Dendas ◽  
B. De Keersmaecker ◽  
M. Aertsen ◽  
W. Develter ◽  
L. De Catte
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Termination Of Pregnancy ◽  
Cns Anomalies

scholarly journals Retrospective Analysis of Pregnancy Terminations: 9-Years Experience at a Tertiary Hospital in Southeastern Turkey

2019 ◽  
pp. 1
Author(s):  
Neslihan Bayramoglu Tepe ◽  
Reyhan Gunduz ◽  
Omer Faruk Dizibuyuk ◽  
Huseyin Caglayan Ozcan ◽  
Tanyeli Guneyligil Kazaz ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Folic Acid ◽  
Risk Groups ◽  
First Trimester ◽  
Prenatal Ultrasound ◽  
Termination Of Pregnancy ◽  
Gestational Week ◽  
Head Neck ◽  
Central Nervous System Anomalies

<p><strong>Objective:</strong> To determine the indications for termination of pregnancy, and their consistency with autopsy data to offer an insight into termination of pregnancy having regard to conditions in Turkey.</p><p><strong>Study Design:</strong> Three hundred and ninety-one pregnancies terminated before the 24th gestational week were enrolled in this study. Maternal age, gravidity, parity, abortion, the status of folic acid usage, consanguineous marital status, gestational week, anomalies that led to termination and pathological diagnoses were recorded. Anomalies that led to termination were grouped as central nervous system , cardiovascular system, gastrointestinal system, genitourinary system, pulmonary, musculoskeletal, head-neck, chromosomal, genetic, multiple anomalies and others. Four groups were formed based on the consistency of prenatal ultrasound diagnosis with pathological diagnosis.</p><p><strong>Results:</strong> Mean age, gravidity, parity, abortion, and gestational week were 28 years, 3, 1, 1, and 15.7 weeks, respectively. One hundred and thirty-eight (35.2%) patients had consanguineous marriage. Three major causes of termination were central nervous system (45.78%), head-neck (17.4%) and multiple anomalies (14%). One hundred and twenty-eight (71.5%) patients with central nervous system anomalies were not using folic acid. Comparison of prenatal ultrasound findings with pathology results, 275 (70.3%) patients had full consistency, 46 (11.8%) had other findings at autopsy besides the confirmed sonographic findings, 34 (8.7%) had some sonographic findings not confirmed at autopsy, and 4 (1%) had no consistency between the findings.</p><p><strong>Conclusion:</strong> Central nervous system anomalies constitute the most common indication for termination of pregnancy in this retrospective study. Low rate of periconceptional folic acid among those cases is remarkable. First-trimester screening for earlier detection of fetal anomalies may be important in high-risk groups such as those with consanguineous marriages. <br /><br /></p>

Central nervous system damage in puerperal sepsis

1926 ◽  
Vol 22 (11) ◽  
pp. 1245-1249
Author(s):  
S. V. Kisin
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Termination Of Pregnancy ◽  
The Other ◽  
Central Nervous System Damage ◽  
Obstetrical Care ◽  
Puerperal Sepsis ◽  
Other Hand

Despite the success of asepsis, the clinic gives us more and more cases of sepsis-postpartum and after miscarriage. Its percentage has continued to grow in recent years, and several factors have contributed to its growth. First of all, in spite of the progress of medicine in general, the situation of obstetrical care in our country, unfortunately, has hardly improved recently, especially in the countryside. On the other hand, the experience must have had such an impact on the organism, that it is reasonable to suppose that mankind is now better able to cope with septic infection than, for instance, in pre-war times. Finally, there is another factor contributing to the increase in the number of septicaemias: the artificial termination of pregnancy, which has become much more frequent in recent times and is especially dangerous in the hands of ignorant healers and midwives.

scholarly journals Comparison of prenatal central nervous system abnormalities with postmortem findings in fetuses following termination of pregnancy and clinical utility of postmortem examination

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Ozge Ozdemir ◽  
Figen Aksoy ◽  
Cihat Sen
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Spina Bifida ◽  
Postmortem Examination ◽  
Termination Of Pregnancy ◽  
High Agreement ◽  
Study Results ◽  
Multiple Abnormalities ◽  
Cns Malformations ◽  
Total Agreement

Abstract Objectives In this study, we aimed to compare prenatal ultrasound (USG) and postmortem examination findings of central nervous system (CNS) abnormalities in fetuses following termination of pregnancy (TOP). Methods A total of 190 fetuses with USG-confirmed fetal CNS abnormalities of terminated pregnancies between January 2001 and January 2017 were retrospectively analyzed and USG and postmortem examination findings were compared. Results The most frequent CNS abnormalities were acrania/anencephaly (n=45, 24%), spina bifida (n=43, 23%), and ventriculomegaly (n=35, 18%). In 144 of the 190 (76%) cases, there was total agreement between USG and postmortem examination diagnosis. Postmortem examination provided minor findings which did not change the major clinical diagnosis in two (1%) cases with spina bifida and ventriculomegaly. In six (3%) cases, the diagnosis changed after postmortem examination. In 25 of the 190 (13%) cases with multiple abnormalities as evidenced by USG, CNS abnormality was unable to be confirmed at postmortem examination. Conclusions Our study results show an overall high agreement (76%) between USG and postmortem examination findings for CNS malformations. Due to autolysis and fluid structure, USG-confirmed CNS diagnosis cannot be always confirmed by postmortem examination. This potential discrepancy should be explained to patients before considering TOP. Postmortem examination is the gold standard to confirm prenatal diagnosis.

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