scholarly journals Retrospective Analysis of Pregnancy Terminations: 9-Years Experience at a Tertiary Hospital in Southeastern Turkey

2019 ◽  
pp. 1
Author(s):  
Neslihan Bayramoglu Tepe ◽  
Reyhan Gunduz ◽  
Omer Faruk Dizibuyuk ◽  
Huseyin Caglayan Ozcan ◽  
Tanyeli Guneyligil Kazaz ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Folic Acid ◽  
Risk Groups ◽  
First Trimester ◽  
Prenatal Ultrasound ◽  
Termination Of Pregnancy ◽  
Gestational Week ◽  
Head Neck ◽  
Central Nervous System Anomalies

<p><strong>Objective:</strong> To determine the indications for termination of pregnancy, and their consistency with autopsy data to offer an insight into termination of pregnancy having regard to conditions in Turkey.</p><p><strong>Study Design:</strong> Three hundred and ninety-one pregnancies terminated before the 24th gestational week were enrolled in this study. Maternal age, gravidity, parity, abortion, the status of folic acid usage, consanguineous marital status, gestational week, anomalies that led to termination and pathological diagnoses were recorded. Anomalies that led to termination were grouped as central nervous system , cardiovascular system, gastrointestinal system, genitourinary system, pulmonary, musculoskeletal, head-neck, chromosomal, genetic, multiple anomalies and others. Four groups were formed based on the consistency of prenatal ultrasound diagnosis with pathological diagnosis.</p><p><strong>Results:</strong> Mean age, gravidity, parity, abortion, and gestational week were 28 years, 3, 1, 1, and 15.7 weeks, respectively. One hundred and thirty-eight (35.2%) patients had consanguineous marriage. Three major causes of termination were central nervous system (45.78%), head-neck (17.4%) and multiple anomalies (14%). One hundred and twenty-eight (71.5%) patients with central nervous system anomalies were not using folic acid. Comparison of prenatal ultrasound findings with pathology results, 275 (70.3%) patients had full consistency, 46 (11.8%) had other findings at autopsy besides the confirmed sonographic findings, 34 (8.7%) had some sonographic findings not confirmed at autopsy, and 4 (1%) had no consistency between the findings.</p><p><strong>Conclusion:</strong> Central nervous system anomalies constitute the most common indication for termination of pregnancy in this retrospective study. Low rate of periconceptional folic acid among those cases is remarkable. First-trimester screening for earlier detection of fetal anomalies may be important in high-risk groups such as those with consanguineous marriages. <br /><br /></p>

scholarly journals Central Nervous System Anomalies Detectable in the First Trimester

2017 ◽  
Vol 11 (4) ◽  
pp. 261-267
Author(s):  
Elsa Viora ◽  
Giulia Polarolo ◽  
Simona Bastonero ◽  
Elena Gullino ◽  
Silvia Stillavato ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Pregnancy Termination ◽  
Fetal Brain ◽  
First Trimester ◽  
Ultrasound Images ◽  
Agenesis Of Corpus Callosum ◽  
Ultrasound Findings ◽  
Fetal Brain Development ◽  
Central Nervous System Anomalies

ABSTRACT Prenatal diagnosis of central nervous system (CNS) congenital anomalies is possible in the second and third trimester. Earlier diagnosis is possible for some of these as the complex acranial/exencephaly/anencephaly and alobar holoprosencephaly (HPE). The knowledge of normal fetal brain development and its ultrasound images at the different weeks’ gestation, the expertise of operators, and high-resolution equipment are essential to obtain good results. The diagnosis in the first trimester of some major anomalies incompatible with extrauterine life or associated with severe handicap is useful to inform the couple, to perform additional examinations, and provide them with the option of earlier and safer pregnancy termination. For some other conditions, like agenesis of corpus callosum and hypoplasia or absence of cerebellar vermis, the diagnosis is possible only in the second trimester, so beware not to falsely reassure or scare expecting parents. In conclusion, first trimester ultrasound could be useful for early detection of some CNS anomalies, but caution could be used for others, particularly in counseling couples about prognostic significant of ultrasound findings. How to cite this article Viora E, Polarolo G, Bastonero S, Gullino E, Stillavato S, Sciarrone A. Central Nervous System Anomalies Detectable in the First Trimester. Donald School J Ultrasound Obstet Gynecol 2017;11(4):261-267.

scholarly journals Prenatal ultrasound findings in Koolen‐de Vries foetuses: Central nervous system anomalies are frequent markers of this syndrome

2021 ◽  
Author(s):  
Fe Amalia García‐Santiago ◽  
Cristina Martínez‐Payo ◽  
Elena Mansilla ◽  
Fernando Santos‐Simarro ◽  
Miguel Ruiz de Azua Ballesteros ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Prenatal Ultrasound ◽  
Ultrasound Findings ◽  
De Vries ◽  
Central Nervous System Anomalies

Fetal Central Nervous System Anomalies According to RT-PCR and Trimester of Maternal Infection with ZIKV. A Prospective Study

2020 ◽  
Author(s):  
Luz Ángela Gutiérrez-Sánchez ◽  
Carlos Hernán Becerra-Mojica ◽  
Mario Augusto Rojas ◽  
Luis Alfonso Díaz-Martínez ◽  
Luis Alfonso Pérez-Vera ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Prospective Study ◽  
Maternal Infection ◽  
Rt Pcr ◽  
A Prospective Study ◽  
Central Nervous System Anomalies

Central nervous system anomalies in two females with Borjeson-Forssman-Lehmann syndrome

2017 ◽  
Vol 69 ◽  
pp. 104-109 ◽  
Author(s):  
Burkhard S. Kasper ◽  
Arnd Dörfler ◽  
Nataliya Di Donato ◽  
Ekkehard M. Kasper ◽  
Dagmar Wieczorek ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Central Nervous System Anomalies

On the Magnus-Kleyn reflexes in organic lesions of the central nervous system

1927 ◽  
Vol 23 (6-7) ◽  
pp. 676-685
Author(s):  
L. I. Omorokov
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Proprioceptive Stimulation ◽  
The Central Nervous System ◽  
Head Neck ◽  
Organic Lesions

The works of R. Magnus and his students in Utrecht discovered and developed the doctrine of special reflexes accompanied by a change in tone depending on the position of the head, neck, torso and members in space. These reflexes, which are called tonic, labyrinth and cervical reflexes, are caused by proprioceptive stimulation coming either from the muscles of the neck (Brondgeest and Shrington) or from the labyrinth (Ewald).

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