A meta-analysis of the effects of intramuscular and intravenous injection of oxytocin on the third stage of labor

2020 ◽  
Vol 301 (3) ◽  
pp. 643-653 ◽  
Author(s):  
Yu Wu ◽  
Huan Wang ◽  
Qi-Yan Wu ◽  
Xiao-Lei Liang ◽  
Jing Wang
Author(s):  
Fatemeh Zahra KARIMI ◽  
Hamid HEIDARIAN MIRI ◽  
Maryam SALEHIAN ◽  
Talat KHADIVZADEH ◽  
Mohaddese BAKHSHI

Background: One of the causes of postpartum hemorrhage is prolongation of third stage of labor. Mother-infant skin to skin contact (SSC) immediately after delivery is one of the non-pharmacological interventions to reduce this stage. Studies which assessed the effect of mother-infant SSC after delivery on duration of the third stage of labor reported controversial results on this issue. Therefore, this study investigated the effect of mother-infant SSC immediately after birth on the duration of third stage of labor Methods: In this systematic review and meta-analysis, the databases of PubMed, Scopus, Cochrane, SID, Magiran IranDoc and Google Scholar were searched from 2000 to 2018, using the keywords related to the objectives of this review to access randomized control trials published in Persian or English. The quality of papers was examined using Cochran's Risk of bias tool. Data was analyzed using Stata software. We used I2 index and Chi-square test to investigate heterogeneity and Egger’s and Begg’s tests to assess publications bias. Random effects model was used to combine the data. Results: Six studies were entered into the meta-analysis. The third stage of labor in SSC group was shorter than that of control group with a mean difference of -1.33 and 95% CI (-2.31 to -0.36) and this difference was statistically significant (P=0.007). Conclusion: Mother-infant SSC decreases the duration of third stage of labor. Therefore, the current study provides some evidences to use this non-pharmacological method in order to accelerate the third stage of labor and ultimately prevent postpartum hemorrhage.  


2021 ◽  
Author(s):  
Maria de Lourdes de Souza ◽  
Adalia Edna Fernando Chipindo ◽  
Eneida Patrícia Teixeira ◽  
Anna Carolina Raduenz Huf Souza ◽  
Rita de Cássia Teixeira Rangel ◽  
...  

Abstract BackgroundPostpartum hemorrhage (PPH) is the most common form of obstetric hemorrhage. This is the main cause of maternal death around the world: the incidence varies among countries and accounts for 27% (in some countries, more than 50%) of direct obstetric maternal deaths, mainly in the postpartum period. Recognizing risk factors for PPH in prenatal care and during childbirth care is the first stage to prevent maternal death from PPH. The objective this review is: To identify the risk factors for hemorrhage in the third stage of labor described in the literature from 2000 to 2020. MethodsA protocol for a Systematic Review and Meta-analysis study was developed, supported by the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) and, registered in the International Prospective Register of Systematic Reviews (PROSPERO). The research question for conducting the review was structured according to the PEOS strategy (P — Populations/People/Patient/ Problem, E — Exposure (s), O — Outcome, S — Study design): P — women aged from 10 to 49 years, in labor; E — risk factors for hemorrhage in the third stage of labor; O — women with hemorrhage during birth and postpartum; S — observational studies (case control and cohort). Thus, the defined question was: what are the risk factors for hemorrhage in the third stage of labor described in the literature from 2000 to 2020? As for the planning of electronic searches, databases were consulted by using the platform of the Coordination for the Improvement of Higher Education Personnel in Brazil (CAPES, as per its Portuguese acronym). Due to the characteristics of each database, specific search strategies were chosen for each database. After applying the eligibility criteria, the articles that are selected will have the quality of the evidence evaluated by applying the Grading of Recommendations, Assessment, Development and Evaluation (GRADE), with the online tool GRADEpro GDT.Discussion Prevention and control of hemorrhage must be initiated in the prenatal period, requiring competent professionals to carry out the appropriate clinical evaluation to classify the degree of risk to which the woman is exposed. This systematic review will support the studies of professionals who working in Angola and Brazil.Systematic review registrationPROSPERO available from: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021219303


Sign in / Sign up

Export Citation Format

Share Document