High-resolution three-dimensional diffusion-weighted MRI/CT image data fusion for cholesteatoma surgical planning: a feasibility study

2014 ◽  
Vol 272 (12) ◽  
pp. 3821-3824 ◽  
Author(s):  
Koji Yamashita ◽  
Akio Hiwatashi ◽  
Osamu Togao ◽  
Kazufumi Kikuchi ◽  
Nozomu Matsumoto ◽  
...  
2014 ◽  
Vol 32 (4) ◽  
pp. 330-341 ◽  
Author(s):  
Kristin L. Granlund ◽  
Ernesto Staroswiecki ◽  
Marcus T. Alley ◽  
Bruce L. Daniel ◽  
Brian A. Hargreaves

Author(s):  
Jung Leng Foo ◽  
Go Miyano ◽  
Thom Lobe ◽  
Eliot Winer

The continuing advancement of computed tomography (CT) technology has improved the analysis and visualization of tumor data. As imaging technology continues to accommodate the need for high quality medical image data, this encourages the research for more efficient ways of extracting crucial information from these vast amounts of data. A new segmentation method using a fuzzy rule based system to segment tumors in a three-dimensional CT data has been developed. To initialize the segmentation process, the user selects the region of interest (ROI) within the tumor in the first image of the CT study set. Using the ROI’s spatial and intensity properties, fuzzy inputs are generated for use in the fuzzy inference system. From a set of predefined fuzzy rules, the system generates a defuzzified output for every pixel in terms of similarity to the object. Pixels with the highest similarity values are selected to be the tumor. This process is repeated for every subsequent slice in the CT set, and the segmented region from the previous slice is used as the ROI for the current slice. This creates a propagation of information from the previous slices, to be used to segment the current slice. The membership functions used during the fuzzification and defuzzification processes are adaptive to the changes in the size and pixel intensities of the current ROI. The proposed method is highly customizable to suit different needs of a user, requiring information from only a single two-dimensional image. Implementing the fuzzy segmentation on two distinct CT sets, the fuzzy segmentation algorithm was able to successfully extract the tumor from the CT image data. Based on the results statistics, the developed segmentation technique is approximately 96% accurate when compared to the results of manual segmentations performed.


1999 ◽  
Vol 5 (S2) ◽  
pp. 186-187
Author(s):  
Joanita Jakarta ◽  
Wah Chiu

Three-dimensional structure studies provide important information about the organization of macromolecules, often revealing biological mechanisms and protein structure-function relationships. 400 KV electron cryo-microscopy is an emerging technology that is proving to be a powerful tool for studying the structures of large macromolecular assemblies that are often not tractable using other techniques. Its large depth of field makes it well-suited for imaging large objects to high resolution. In addition, a high accelerating voltage minimizes chromatic aberration yielding images of higher contrast. Recently a 400 KV electron cryo-microscope has been used to image periodic arrays of tubulin to 3.5 Å and single particles at somewhat lower resolutions (13 Å) providing practical demonstrations of its usefulness in modern structural biology. In this paper we present high resolution image data of two large icosahedral viruses: herpes simplex virus IB nucleocapsid (HSV IB) and rice dwarf virus (RDV). Human herpes virus (HSV) is associated with a spectrum of diseases ranging from cold sores to more severe clinical manifestations such as mental retardation.


Brachytherapy ◽  
2017 ◽  
Vol 16 (5) ◽  
pp. 956-963 ◽  
Author(s):  
Antoine Schernberg ◽  
Corinne Balleyguier ◽  
Isabelle Dumas ◽  
Sébastien Gouy ◽  
Alexandre Escande ◽  
...  

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