The level and extent of upper airway obstruction affects the severity of laryngopharyngeal reflux

2018 ◽  
Vol 275 (9) ◽  
pp. 2415-2416
Author(s):  
Zhengcai Lou ◽  
Zi-Han Lou
Keyword(s):  
Airway Obstruction ◽  
Laryngopharyngeal Reflux ◽  
Upper Airway ◽  
Upper Airway Obstruction

The Aerodigestive Clinic: Multidisciplinary Management of Pediatric Dysphagia

2008 ◽  
Vol 17 (3) ◽  
pp. 101-109 ◽  
Author(s):  
Laura Haibeck ◽  
David L. Mandell
Keyword(s):  
Young Children ◽  
Airway Obstruction ◽  
Multidisciplinary Approach ◽  
Laryngopharyngeal Reflux ◽  
Upper Airway ◽  
Upper Airway Obstruction ◽  
Pediatric Airway ◽  
Common Causes ◽  
The Individual ◽  
The Relationship

Abstract The purposes of this article are (a) to explore the relationship between pediatric upper airway obstruction and dysphagia and (b) to highlight the benefits of using a multidisciplinary approach when assessing infants and children with upper respiratory and swallowing disorders. The functions of breathing and swallowing are tightly coordinated in infants and young children, and pediatric upper airway disorders can often adversely affect the swallowing mechanism and may even predispose the individual to aspiration. Some of the more common causes of pediatric airway obstruction seen in this setting are laryngomalacia, vocal fold paralysis, laryngeal cleft, and Pierre Robin's sequence. In the setting of all of these disorders, associations may also exist with gastroesophageal reflux (GER) and laryngopharyngeal reflux, and this topic is also reviewed. In the multidisciplinary assessment of young children with aerodigestive disorders, fiberoptic flexible endoscopic evaluation of swallowing has gained traction as a useful test for simultaneous evaluation of pediatric upper airway obstruction and dysphagia and has provided complimentary information to the more traditional pediatric videofluoroscopic swallowing evaluation. A representative case study is provided that illustrates the relationship between pediatric upper airway obstruction and dysphagia and demonstrates the effectiveness of a multidisciplinary approach.

THE COMPARISON OF CONFIGURATION, DEGREE AND SITES OF OBSTRUCTION IN PATIENTS WITH SLEEP DISORDERED BREATHING: EXAMINATION USING DRUG-INDUCED SLEEP ENDOSCOPY, MUELLER MANEUVER AND POLYSOMNOGRAPHY

2020 ◽  
pp. 54-57
Author(s):  
NIKEN AGENG RIZKI ◽  
SUSYANA TAMIN ◽  
FAUZIAH FARDIZZA ◽  
RETNO S. WARDANI ◽  
ARIEF MARSABAN ◽  
...  
Keyword(s):  
Airway Obstruction ◽  
Laryngopharyngeal Reflux ◽  
Nasal Congestion ◽  
Upper Airway ◽  
Upper Airway Obstruction ◽  
Sleep Endoscopy ◽  
Drug Induced ◽  
Drug Induced Sleep Endoscopy ◽  
Obstructive Sleep ◽  
Mueller Maneuver

Objective: The purpose of this study is to evaluate the location, configuration, and degree of differences in upper airway obstruction between the Mueller Maneuver (MM) and Drug-induced sleep endoscopy (DISE), thus acquiring a better diagnostic value for SDB patients. Methods: A cross-sectional and analytical descriptive study using retrospective secondary data to evaluate the location, configuration and degree of upper airway obstruction in SDB subjects using the Mueller Maneuver and DISE. Polysomnography (PSG) type 2 was used to determine the SDB degree. Results: Subjects with SDB non-Obstructive sleep apnea (OSA) and OSA show a multilevel obstruction with a different location and configuration due to the various risk factors, such as nasal congestion, laryngopharyngeal reflux, obesity and menopause. Conclusion: Statistical differences in upper airway obstruction configuration between MM and DISE were found in the level of the velum (p=0,036), oropharynx (p<0,001) and epiglottis (p=0,036) and were also found in the obstruction degree of the velum, oropharynx, tongue base and epiglottis with p=0,002; p<0,001; p<0,001 and p<0,001. No statistical difference was found on the lowest oxygen saturation between PSG and DISE (p=0,055).

scholarly journals Classification of directionally specific vagus nerve activity using an upper airway obstruction model in anesthetized rodents

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
P. Sabetian ◽  
Y. Sadat-Nejad ◽  
Paul B. Yoo
Keyword(s):  
Airway Obstruction ◽  
Upper Airway ◽  
Low Noise ◽  
Upper Airway Obstruction ◽  
Gaussian Kernel ◽  
Recording Electrode ◽  
Cuff Electrode ◽  
Nerve Cuff ◽  
Svm Model ◽  
Nerve Cuff Electrode

AbstractElectrical signals from the peripheral nervous system have the potential to provide the necessary motor, sensory or autonomic information for implementing closed-loop control of neuroprosthetic or neuromodulatory systems. However, developing methods to recover information encoded in these signals is a significant challenge. Our goal was to test the feasibility of measuring physiologically generated nerve action potentials that can be classified as sensory or motor signals. A tetrapolar recording nerve cuff electrode was used to measure vagal nerve (VN) activity in a rodent model of upper airway obstruction. The effect of upper airway occlusions on VN activity related to respiration (RnP) was calculated and compared for 4 different cases: (1) intact VN, (2) VN transection only proximal to recording electrode, (3) VN transection only distal to the recording electrode, and (4) transection of VN proximal and distal to electrode. We employed a Support Vector Machine (SVM) model with Gaussian Kernel to learn a model capable of classifying efferent and afferent waveforms obtained from the tetrapolar electrode. In vivo results showed that the RnP values decreased significantly during obstruction by 91.7% ± 3.1%, and 78.2% ± 3.4% for cases of intact VN or proximal transection, respectively. In contrast, there were no significant changes for cases of VN transection at the distal end or both ends of the electrode. The SVM model yielded an 85.8% accuracy in distinguishing motor and sensory signals. The feasibility of measuring low-noise directionally-sensitive neural activity using a tetrapolar nerve cuff electrode along with the use of an SVM classifier was shown. Future experimental work in chronic implant studies is needed to support clinical translatability.

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