The predictive role of neutrophil-to-lymphocyte ratio in the outcomes of patients with sarcomatoid carcinoma of oral cavity

2021 ◽  
Author(s):  
Roshankumar Patil ◽  
Prakash Pandit ◽  
Vijay Palwe ◽  
Rahul Patil ◽  
Sucheta Gandhe ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Sarcomatoid Carcinoma ◽  
Neutrophil To Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Predictive Role

Predictive role of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in normal-tension glaucoma

2017 ◽  
Vol 103 ◽  
pp. 54-56 ◽  
Author(s):  
Kursat Atalay ◽  
Havva Kaldirim Erdogan ◽  
Ahmet Kirgiz ◽  
Senay Asik Nacaroglu
Keyword(s):  
Normal Tension Glaucoma ◽  
Neutrophil To Lymphocyte Ratio ◽  
Platelet To Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Predictive Role

scholarly journals 83 The predictive role of neutrophil-to-lymphocyte ratio in post-operative cardiopulmonary bypass surgery

2021 ◽  
Vol 23 (Supplement_G) ◽  
Author(s):  
Valentina Bucciarelli ◽  
Francesco Bianco ◽  
Annaclara Blasi ◽  
Martina Primavera ◽  
Baldinelli Alessandra ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Cardiopulmonary Bypass ◽  
Pediatric Patients ◽  
Septal Defect ◽  
Left Ventricular ◽  
Conduction System ◽  
Neutrophil To Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Predictive Role

Abstract Aims Postoperative arrhythmias (POA) are a common complication after cardiac surgical repairs for congenital heart disease (CHD), representing a substantial source of morbidity, mortality, and prolonged total in-hospital stay, with an incidence of 7.5–48% in postoperative pediatric cardiac patients. The etiology is multifactorial, and it has been related to the direct surgical manipulation of the cardiac conduction system, to the local tissue inflammation in the myocardium adjacent to the conduction system and to the arrhythmogenic effects of cardiopulmonary bypass (CPB), inotropes, and electrolyte disturbances. Recently, the prognostic role of neutrophil-to-lymphocyte ratio (NLR), a novel inflammation marker, has been evaluated in pediatric patients after CPB surgery. To evaluate the predictive role of NLR in POA in a population of pediatric CHD patients after CPB. Methods and results We retrospectively collected perioperative clinical and laboratory data of 146 patients (age 8.27 ± 10.79 years; male gender: 60.8%) consecutively admitted to the cardiac surgery intensive care unit (ICU) of our institute after elective cardiac surgery with CPB in 2018. We grouped and analyzed our population over NLR tertiles evaluated at 24 h from CPB and types of POA: supraventricular (SVT) and junctional (JET). The prognostic value of NLR and its association with POA was analyzed. Diagnoses of 146 patients included atrial septal defect (n = 36), ventricular septal defect (n = 20), pulmonary atresia/stenosis (n = 10), tetralogy of Fallot (n = 20), endocardial cushion defect (n = 8), left ventricular outflow tract obstruction (n = 14), anomalous origin of coronary artery (n = 6), complex CHD (n = 13), interrupted/hypoplastic aortic arch (n = 12), anomalous pulmonary venous return (n = 3). The mean CPB time was 121.6 ± 84.6 min. The median ICU hospitalization was 48 h [Q1, Q3: 24, 96]. Twelve patients experienced POA: 6 SVT and 6 JET. The frequency of POA incremented over NLR-tertiles (P-Trend 0.017), while SVT onset was associated with higher values of NLR and C-reactive protein (P = 0.034 and P = 0.011, respectively). Patients in the second and third tertiles of NLR had a prolonged hospitalization (log-rank, P = 0.029), especially when associated with POA (log-rank, P = 0.012). At the multivariable analysis, higher age and NLR values were independently associated with SVT [OR per year 1.22; 95% CI (1.02, 1.25), P = 0.043 and OR per point 1.91; 95% CI (1.29, 2.82), P = 0.012, respectively], but not with JET. Conclusions 24-h post-CPB NLR can predict postoperative SVT in a population of pediatric CHD patients. Our data suggest that the NLR could be a useful, easy-to-obtain marker for postoperative outcome in pediatric patients who had undergone elective CPB.

Predictive role of neutrophil-to-lymphocyte ratio in preeclampsia: A meta-analysis including 3982 patients

2020 ◽  
Vol 20 ◽  
pp. 111-118 ◽  
Author(s):  
Qingling Kang ◽  
Wei Li ◽  
Nan Yu ◽  
Lei Fan ◽  
Yang Zhang ◽  
...  
Keyword(s):  
Meta Analysis ◽  
Neutrophil To Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Predictive Role

scholarly journals Role of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio as prognostic markers in oral cavity cancers

2019 ◽  
Vol 40 (1) ◽  
pp. 94
Author(s):  
Aseem Mishra ◽  
Akshat Malik ◽  
Manish Mair ◽  
Swagnik Chakrabarti ◽  
Apurva Garg ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Prognostic Markers ◽  
Neutrophil To Lymphocyte Ratio ◽  
Platelet To Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Oral Cavity Cancers

scholarly journals Neutrophil-to-lymphocyte Ratio and Platelet-to-lymphocyte Ratio in the Prediction of Pancreatic Cancer Patients’ prognosis: a retrospective study

2019 ◽  
Author(s):  
Yungu Chen ◽  
Lek Man Lam ◽  
Lina He ◽  
Yiu Sing Tsang ◽  
Qing Xia
Keyword(s):  
Pancreatic Cancer ◽  
Cox Regression ◽  
Neutrophil To Lymphocyte Ratio ◽  
Platelet To Lymphocyte Ratio ◽  
Prognostic Predictor ◽  
Lymphocyte Ratio ◽  
Significant Difference ◽  
Predictive Role ◽  
Selection Of

Abstract Background Although neutrophil-to-lymphocyte ratio (NLR) and a high platelet-to-lymphocyte ratio (PLR) have been reported to be an inverse prognostic predictor of survival in patients with pancreatic cancer (PC), the comparison of their prognostic roles in patients with PC undergoing gemcitabine-based chemotherapy and 5-fluorouracil (5-FU) remains unclear. Methods This study was designed and performed to determine the predictive role of NLR and PLR in patients diagnosed with PC who underwent one of these two regimens. We retrospectively enrolled 95 patients diagnosed with PC undergoing supportive care, gemcitabine-based chemotherapy or 5-FU therapy from January 2015 to October 2018. Univariate and multivariate Cox regression analyses were done to identify clinicopathological predictors of time to treatment failure (TTF) and overall survival (OS), including pretreatment NLR and PLR. Results Pretreatment NLR was significantly associated with metastasis. Pretreatment NLR was an independent prognostic predictor of both TTF and OS for patients with PC, with NLR>4.0 predicting worse survival. PLR, however, didn’t independently predict TTF or OS. There were no significant difference in the OS of patients undergoing gemcitabine-based regimens and 5-FU regimens when divided into two subgroups: NLR≤4.0 and >4.0. Conclusions Pretreatment NLR is a promising independent outcome predictor for patients with PC. The predictive value of PLR might not be as good as NLR. NLR might not be a suitable factor in the selection of regimens for patients with PC in term of gemcitabine and 5-FU.

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