scholarly journals Efficacy of infliximab in neuro-Behçet’s disease presenting with isolated longitudinally extensive transverse myelitis

2013 ◽  
Vol 260 (12) ◽  
pp. 3167-3170 ◽  
Author(s):  
Ryo Kuroda ◽  
Junko Suzuki ◽  
Mizuho Muramatsu ◽  
Asami Tasaki ◽  
Mariko Yano ◽  
...  
2021 ◽  
pp. 78-83
Author(s):  
Shunya Fujiwara ◽  
Yasuhiro Manabe ◽  
Yumiko Nakano ◽  
Yoshio Omote ◽  
Taijun Yunoki ◽  
...  

We report 2 cases of probable neuro-Behçet’s disease (NBD) with longitudinally extensive transverse myelitis (LETM). In both cases, the patients presented paraplegia, as well as sensory, bladder, and rectal disturbances. Magnetic resonance imaging (MRI) of patient 1 showed continuous high signal intensity extending from the midbrain to the entire spinal cord in the central part of the cord on T2-weighted imaging (T2WI). Spinal MRI of patient 2 revealed high signal intensity extending from Th2 to Th10 in the central part of the cord on T2WI. Both patients received high-dose methylprednisolone. A continuous lesion from the midbrain to the entire spinal cord as in patient 1 has not been previously reported. Patient 2 dramatically improved by infliximab therapy. The present cases suggest that NBD should be considered as a differential diagnosis in patients with LETM.


2004 ◽  
Vol 24 (1) ◽  
pp. 64-66 ◽  
Author(s):  
Meral Çalgüneri ◽  
Ahmet Mesut Onat ◽  
M. Akif Öztürk ◽  
Levent Özçakar ◽  
Kemal Ureten ◽  
...  

2012 ◽  
Vol 19 (1) ◽  
pp. 39
Author(s):  
Han-Jun Bae ◽  
Chang Gyu Jung ◽  
Ju Hyung Lee ◽  
Tae Yul Kim ◽  
Sunyoung Lee ◽  
...  

2007 ◽  
Vol 30 (3) ◽  
pp. 294-296 ◽  
Author(s):  
Levent Sinan Bir ◽  
Fatma Özdemir Eşmeli ◽  
Utku Cenikli ◽  
×ağdaş Erdoğan ◽  
Eylem Değirmenci

2015 ◽  
Vol 22 (7) ◽  
pp. 960-963 ◽  
Author(s):  
Hyung Seok Lee ◽  
Do Young Kim ◽  
Ha Young Shin ◽  
Young-Chul Choi ◽  
Seung Min Kim

Background: Spinal cord involvement in Behçet’s disease is not well studied. Objective: To evaluate the clinical, laboratory and magnetic resonance imaging characteristics of spinal cord involvement in Behçet’s disease. Methods: We retrospectively reviewed 10 spinal cord involvements in seven patients with Behçet’s disease. Results: The median age of onset for spinal cord involvement was 32 (23–45 years). Two patients showed a secondary progressive course. Cerebrospinal fluid findings revealed mild to moderate pleocytosis and/or elevated protein levels. In eight spinal cord involvements, the lesion was longer than three vertebrae. Serum anti-aquaporin-4 antibody was negative in all four patients tested. Conclusions: Longitudinally extensive transverse myelitis is a characteristic manifestation of spinal cord involvement in Behçet’s disease.


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