scholarly journals Two Cases of Probable Neuro-Behçet’s Disease with Longitudinally Extensive Transverse Myelitis

2021 ◽  
pp. 78-83
Author(s):  
Shunya Fujiwara ◽  
Yasuhiro Manabe ◽  
Yumiko Nakano ◽  
Yoshio Omote ◽  
Taijun Yunoki ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Signal Intensity ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Transverse Myelitis ◽  
High Signal Intensity ◽  
High Signal ◽  
Longitudinally Extensive Transverse Myelitis ◽  
Behcet's Disease ◽  
Extensive Transverse Myelitis

We report 2 cases of probable neuro-Behçet’s disease (NBD) with longitudinally extensive transverse myelitis (LETM). In both cases, the patients presented paraplegia, as well as sensory, bladder, and rectal disturbances. Magnetic resonance imaging (MRI) of patient 1 showed continuous high signal intensity extending from the midbrain to the entire spinal cord in the central part of the cord on T2-weighted imaging (T2WI). Spinal MRI of patient 2 revealed high signal intensity extending from Th2 to Th10 in the central part of the cord on T2WI. Both patients received high-dose methylprednisolone. A continuous lesion from the midbrain to the entire spinal cord as in patient 1 has not been previously reported. Patient 2 dramatically improved by infliximab therapy. The present cases suggest that NBD should be considered as a differential diagnosis in patients with LETM.

Spinal cord involvement in Behçet’s disease

2015 ◽  
Vol 22 (7) ◽  
pp. 960-963 ◽  
Author(s):  
Hyung Seok Lee ◽  
Do Young Kim ◽  
Ha Young Shin ◽  
Young-Chul Choi ◽  
Seung Min Kim
Keyword(s):  
Spinal Cord ◽  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Clinical Laboratory ◽  
Age Of Onset ◽  
Behçet's Disease ◽  
Transverse Myelitis ◽  
Behcet's Disease ◽  
Spinal Cord Involvement ◽  
Imaging Characteristics

Background: Spinal cord involvement in Behçet’s disease is not well studied. Objective: To evaluate the clinical, laboratory and magnetic resonance imaging characteristics of spinal cord involvement in Behçet’s disease. Methods: We retrospectively reviewed 10 spinal cord involvements in seven patients with Behçet’s disease. Results: The median age of onset for spinal cord involvement was 32 (23–45 years). Two patients showed a secondary progressive course. Cerebrospinal fluid findings revealed mild to moderate pleocytosis and/or elevated protein levels. In eight spinal cord involvements, the lesion was longer than three vertebrae. Serum anti-aquaporin-4 antibody was negative in all four patients tested. Conclusions: Longitudinally extensive transverse myelitis is a characteristic manifestation of spinal cord involvement in Behçet’s disease.

scholarly journals NEURO-BEHÇET’S DISEASE ONSET – A DIAGNOSTIC CHALLENGE

2016 ◽  
Vol 25 (1) ◽  
pp. 46-50
Author(s):  
Casandra Buzatu ◽  
◽  
Sanziana Daia ◽  
Ruxandra Ionescu ◽  
◽  
...  
Keyword(s):  
Spinal Cord ◽  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Disease Onset ◽  
Transverse Myelitis ◽  
Lower Limbs ◽  
Neurological Manifestations ◽  
Diagnostic Challenge ◽  
Behcet's Disease

We are presenting the case of a 51 years old female diagnosed with Neuro-Behçet’s disease, undergoing immunosuppression and corticoid therapy in the present. The onset was with recurrent oral ulcerations. Neurological manifestations progressed rapidly from paresthesia in the upper and lower limbs to corset-like hypoesthesia of the abdominal wall and sphincterian incontinence. MRI of the spinal cord showed Transverse Myelitis.

Transverse myelitis in a patient with Behcet’s disease: favorable outcome with a combination of interferon-α

2004 ◽  
Vol 24 (1) ◽  
pp. 64-66 ◽  
Author(s):  
Meral Çalgüneri ◽  
Ahmet Mesut Onat ◽  
M. Akif Öztürk ◽  
Levent Özçakar ◽  
Kemal Ureten ◽  
...  
Keyword(s):  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Transverse Myelitis ◽  
Favorable Outcome ◽  
Interferon Α ◽  
Behcet's Disease

Tubercular longitudinally extensive transverse myelitis with lower motor neuron paralysis

2020 ◽  
pp. 004947552095644
Author(s):  
Manjeet Kumar Goyal ◽  
Mahesh Lal
Keyword(s):  
Spinal Cord ◽  
Motor Neuron ◽  
Spinal Tuberculosis ◽  
Transverse Myelitis ◽  
Lower Motor Neuron ◽  
Neuron Type ◽  
Longitudinally Extensive Transverse Myelitis ◽  
Longitudinal Extensive Transverse Myelitis ◽  
Spinal Segments ◽  
Extensive Transverse Myelitis

Transverse myelitis typically extends two or less spinal segments, whereas longitudinal extensive transverse myelitis (LETM) extends three or more spinal segments in length and may occasionally span all the segments of the spinal cord. We present a case of spinal tuberculosis presenting with LETM with true lower motor neuron-type flaccid paraplegia.

scholarly journals Transverse Myelitis in Patient with Behçet's Disease

2012 ◽  
Vol 19 (1) ◽  
pp. 39
Author(s):  
Han-Jun Bae ◽  
Chang Gyu Jung ◽  
Ju Hyung Lee ◽  
Tae Yul Kim ◽  
Sunyoung Lee ◽  
...  
Keyword(s):  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Transverse Myelitis ◽  
Behcet's Disease
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