Vessel density, retinal thickness, and choriocapillaris vascular flow in myopic eyes on OCT angiography

2018 ◽  
Vol 256 (8) ◽  
pp. 1419-1427 ◽  
Author(s):  
Paolo Milani ◽  
Giovanni Montesano ◽  
Luca Rossetti ◽  
Fulvio Bergamini ◽  
Alfredo Pece
Keyword(s):  
Retinal Thickness ◽  
Vessel Density ◽  
Oct Angiography ◽  
Vascular Flow

scholarly journals Reduced Macular Vessel Density and Capillary Perfusion in Glaucoma Detected Using OCT Angiography

2019 ◽  
Vol 44 (5) ◽  
pp. 533-540 ◽  
Author(s):  
Jiahui Wu ◽  
Rani T. Sebastian ◽  
Colin J. Chu ◽  
Freia McGregor ◽  
Andrew D. Dick ◽  
...  
Keyword(s):  
Vessel Density ◽  
Oct Angiography ◽  
Capillary Perfusion

scholarly journals Evidence of Post Trabeculectomy Optic Nerve Reperfusion by OCT Angiography

2020 ◽  
pp. 35-39
Author(s):  
Jigyasa Sahu
Keyword(s):  
Intraocular Pressure ◽  
Optic Nerve ◽  
Nerve Fiber ◽  
Structural Parameters ◽  
Visual Fields ◽  
Vessel Density ◽  
Oct Angiography ◽  
Prognostic Indicators ◽  
Fiber Layer ◽  
Nerve Fiber Layer

Aim: To describe a case of glaucoma which showed increase in optical coherence tomography (OCT) angiographic vessel densities after intraocular pressure reduction suggesting reperfusion of optic nerve. Presentation of Case: A 55 year old female with primary open angle glaucoma was taken up for trabeculectomy in view of inadequate control of intraocular pressure (IOP) despite maximal medical therapy. In addition to routine glaucoma assessment by visual fields and nerve fiber layer assessment by OCT, OCT angiographic evaluation of peripapillary vessel density was done preoperatively. Three months after trabeculectomy, her intraocular pressure decreased from 35mmHg to 14mmHg. Compared with the preoperative baseline value, the vessel density increased significantly in all quadrants after three months from surgery as demonstrated by OCT angiography. Discussion: This case report suggests that decreased optic nerve head perfusion due to high IOP can be reversed by reduction of IOP. Conclusion: Vascular parameters like angiographic vessel density can show reversible changes as decreased blood flow reinstates and thus can be better prognostic indicators than structural parameters like OCT retinal nerve fiber layer (RNFL) in glaucoma patients.

scholarly journals Comparison of inner macular thickness and superficial macular capillary vessel density acquired using classic and high-definition optical coherence tomography angiography scans

2021 ◽  
Vol 3 (1) ◽  
pp. 43-54
Author(s):  
Gabor Hollo
Keyword(s):  
Optical Coherence Tomography ◽  
Retinal Thickness ◽  
Open Angle Glaucoma ◽  
Imaging Study ◽  
Vessel Density ◽  
Optical Coherence ◽  
High Definition ◽  
Normal Value ◽  
Image Area ◽  
Clinically Significant

Background: In ophthalmology, thickness and vessel density (VD) measurements for the 6 x 6 mm inner macular retinal area have received increasing attention in glaucomatous progression research. For this area, the Angiovue optical coherence tomography system introduced a 304 x 304 A/B scans function (classic Angio Retina scan) in 2014, and a 400 x 400 A/B scans function (high-definition [HD] Angio Retina scan) in 2017. These scan types cannot be used in combination for the software provided for progression analysis.Purpose: Since losing data for 3 years may negatively influence progression analysis, we investigated whether clinically significant differences exist between consecutive measurements acquired with these scan types on the same eyes.Methods: As a part of our noninterventional prospective glaucoma imaging study, primary-open-angle glaucoma patients (POAG group), and ocular hypertensive and healthy control participants (structurally undamaged group) were imagedusing both the classic and the HD Angio Retina scans, respectively, without changing the patients’ position. High-quality images were obtained on 12 POAG eyes of 12 consecutive POAG patients, and 10 healthy and ocular hypertensive eyes of 10 consecutive participants before the data collection had to be suspended due to the new coronavirus epidemic.Results: For Early Treatment Diabetic Retinopathy Study image area, the mean difference (classic minus HD value) was 0.02 ± 0.37 μm for inner retinal thickness (P = 0.869) and 0.33 ± 1.33 % (P = 0.452) for superficial capillary VD in the structurally normal group (between-methods difference: ≤ 0.8% of the respective normal value). In the POAG group, the corresponding figures were -0.07 ± 1.22 μm for inner retinal thickness (P = 0.854; between-methods difference: 0.6% of the normal value) and 1.12 ± 2.58 % for superficial capillary VD (P = 0.158; classic scan value minus HD scan value: 1.12 ± 2.58 %; 2.3% of the normal value).Conclusion: Our results suggest that combined use of thickness and VD values for structurally normal eyes and thickness values for POAG eyes derived from classic and HD scans, respectively, for progression analysis can be reasonable since the differences between the corresponding values are small. However, combining the corresponding VD parameters for POAG eyes is useful only when the follow-up time before the scan type change is long enough to counterbalance the effect of the change on the result.  

scholarly journals Vessel Density and Retinal Thickness from Optical Coherence Tomography Angiography as New Indexes in Adolescent Myopia

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Qin Zhu ◽  
Chunwen Chen ◽  
Jingyan Yao
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Retinal Thickness ◽  
Blood Perfusion ◽  
Cross Sectional Study ◽  
Vessel Density ◽  
Optical Coherence ◽  
Cross Sectional ◽  
Foveal Region ◽  
Almost All

Purpose. To evaluate and quantify blood perfusion and retinal thickness (RT) from the perspective of quadrants by optical coherence tomography angiography (OCTA) in adolescents with myopia and explore the relationship between axial elongation and related indexes of OCTA. Methods. A total of 88 subjects (149 eyes) with different degrees of myopia were included in this cross-sectional study. Vessel density (VD) and RT of quadrants in macular and peripheral regions were measured through OCTA. Results. The superficial VD (SVD) of the parainferior region was significantly correlated with axial length (AL) between the emmetropia (EM) group and high myopia (HI) group ( P = 0.012 ). There were significant differences in deep VD (DVD) in all quadrants, except for the foveal, perifoveal, and peri-inferior regions ( P > 0.05 ). However, there were significant alterations in the whole, parainferior, and perinasal regions ( P = 0.030 , 0.023, and 0.035) in the low-to-moderate myopia (L–M) group compared with those in the HI group. There were significant differences in the RT in all quadrants, except for the foveal, paratemporal, and paranasal regions ( P > 0.05 ) between the EM and L–M groups and the foveal region ( P > 0.05 ) between the EM and HI groups. Nevertheless, only RT in the peri-inferior region of the L–M and HI groups showed significant differences. AL was negatively correlated with SVD in the perifoveal and parainferior regions (r = −0.179, P = 0.029 ; r = −0.227, P = 0.005 ) and inversely correlated with DVD and RT in almost all quadrants, except for the foveal region (r = −0.020, P = 0.811 ; r = 0.135, P = 1.000 ). Conclusion. DVD and RT were closely associated with the severity of myopia and might be new indexes in assessing and detecting myopia development via OCTA.

Determination of peripapillary vessel density in optic disc drusen using EDI-OCT and OCT angiography

2020 ◽  
Vol 197 ◽  
pp. 108123
Author(s):  
Anne-Sofie Wessel Lindberg ◽  
Vedrana Andersen Dahl ◽  
Isabelle Karlesand ◽  
Lea Lybek Rueløkke ◽  
Lasse Malmqvist ◽  
...  
Keyword(s):  
Optic Disc ◽  
Vessel Density ◽  
Oct Angiography ◽  
Optic Disc Drusen
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