A cytogenetic study of hospital workers occupationally exposed to radionuclides in Serbia: premature centromere division as novel biomarker of exposure?

2015 ◽  
Vol 89 (3) ◽  
pp. 477-484 ◽  
Author(s):  
Jelena Pajic ◽  
Boban Rakic ◽  
Dubravka Jovicic ◽  
Aleksandar Milovanovic
CYTOLOGIA ◽  
1995 ◽  
Vol 60 (2) ◽  
pp. 159-165
Author(s):  
M. I. Arrieta ◽  
B. Martínez ◽  
M. Nuñez ◽  
A. Gil ◽  
A. Echarri ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
César Paz-y-Miño ◽  
Nadia Cumbal ◽  
María Eugenia Sánchez

Genotoxicity studies in Ecuador have been carried out during the past two decades. The focuses of the research were mainly the area of environmental issues, where the populations have been accidentally exposed to contaminants and the area of occupational exposure of individuals at the workplace. This paper includes studies carried out in the population of the Amazon region, a zone known for its rich biodiversity as well as for the ecological damage caused by oil spills and chemical sprayings whose consequences continue to be controversial. Additionally, we show the results of studies comprised of individuals occupationally exposed to toxic agents in two very different settings: flower plantation workers exposed to pesticide mixtures and X-ray exposure of hospital workers. The results from these studies confirm that genotoxicity studies can help evaluate current conditions and prevent further damage in the populations exposed to contaminants. As such, they are evidence of the need for biomonitoring employers at risk, stricter law enforcement regarding the use of pesticides, and increasingly conscientious oil extraction activities.


1998 ◽  
Vol 21 (2) ◽  
pp. 263-266
Author(s):  
Denise Pagni ◽  
Maria Isabel Melaragno

Etiology of premature ovarian failure (POF) is unclear in most patients. Since some cases are related to X-chromosome abnormalities, cytogenetical studies were conducted in patients with POF. Lymphocyte cultures from eleven patients were compared to cultures from age-matched controls. All individuals presented normal karyotypes. Frequencies of aneuploid and structural chromosome aberrations did not differ between the groups. The X chromosome was more frequently involved in aneuploidy and in premature centromere division in both groups.


1991 ◽  
Vol 48 (2) ◽  
pp. 98-102 ◽  
Author(s):  
F Martin ◽  
R Earl ◽  
E J Tawn

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