Agreement between core needle biopsy and surgical excision product: the importance of the invasive breast carcinoma grading system

2021 ◽  
Author(s):  
Rodrigo Justi Nogueira ◽  
Thales Müller Silvério Alves ◽  
Mário Jefferson Quirino Louzada ◽  
Deolino João Camilo-Júnior ◽  
José Cândido Caldeira Xavier-Júnior
Keyword(s):  
Breast Carcinoma ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Surgical Excision ◽  
Invasive Breast Carcinoma ◽  
Grading System ◽  
Core Needle

scholarly journals Invasive Breast Carcinoma Tumor Size on Core Needle Biopsy: Analysis of Practice Patterns and Effect on Final Pathologic Tumor Stage

2018 ◽  
Vol 18 (5) ◽  
pp. e1027-e1030 ◽  
Author(s):  
Emmanuel Agosto-Arroyo ◽  
Maryam Tahmasbi ◽  
Sameer Al Diffalha ◽  
Laila Khazai ◽  
Yin Xiong ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Core Needle Biopsy ◽  
Tumor Size ◽  
Needle Biopsy ◽  
Practice Patterns ◽  
Tumor Stage ◽  
Invasive Breast Carcinoma ◽  
Core Needle ◽  
Carcinoma Tumor

Blood Dissemination of Mammaglobin-Specific RNA During Core Needle Biopsy in Patients with Invasive Breast Carcinoma

2004 ◽  
Vol 10 (1) ◽  
pp. 61-62
Author(s):  
Kurt Grunewald ◽  
Margot Haun ◽  
Michael Fiegl ◽  
Gunther Gastl ◽  
Christian Marth ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Invasive Breast Carcinoma ◽  
Core Needle

Management of BIRADS 3, 4A, and 4B Lesions Diagnosed as Pure Papilloma by Ultrasound-Guided Core Needle Biopsy: Is Surgical Excision Necessary?

2019 ◽  
Vol 26 (7) ◽  
pp. 909-914 ◽  
Author(s):  
Sean D. Raj ◽  
Jordana Phillips ◽  
Tejas S. Mehta ◽  
Liza M. Quintana ◽  
Michael D. Fishman ◽  
...  
Keyword(s):  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Surgical Excision ◽  
Ultrasound Guided ◽  
Core Needle

Benign breast papillomas without atypia diagnosed with core needle biopsy: Outcome of surgical excision and imaging follow-up

2020 ◽  
Vol 131 ◽  
pp. 109237
Author(s):  
Dogan S. Polat ◽  
Emily E. Knippa ◽  
Ramapriya Ganti ◽  
Stephen J. Seiler ◽  
Sally H. Goudreau
Keyword(s):  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Surgical Excision ◽  
Core Needle

Papillary lesions of the breast: Can larger core needle biopsy samples identify patients who may avoid surgical excision?

2012 ◽  
Vol 30 (27_suppl) ◽  
pp. 44-44
Author(s):  
Alice P. Chung ◽  
Kelly T. Huynh ◽  
Jaime Shamonki ◽  
Myung-Shin Sim ◽  
Camelia Lawrence ◽  
...  
Keyword(s):  
Core Needle Biopsy ◽  
Predictive Value ◽  
Needle Biopsy ◽  
Surgical Excision ◽  
Tissue Samples ◽  
Core Needle ◽  
Ductal Hyperplasia ◽  
Benign Histology ◽  
Papillary Lesions ◽  
Malignant Lesions

44 Background: Papillary lesions of the breast are frequently diagnosed on core needle biopsy (CNB). The ability to distinguish benign from atypical/malignant papillary lesions is limited by the representative nature of the biopsy method; thus follow-up excision is usually recommended. We aimed to determine if larger CNB samples can more reliably predict the true benign nature of a papillary lesion, thereby sparing certain patients a formal surgical excision. Methods: We reviewed medical records of 53 female patients diagnosed with histologically benign papillary lesions on CNB from 2000 to 2010, who subsequently underwent surgical excision. Pathology slides of the CNB were reviewed to document the benign histologic features of the papilloma, the number of cores sampled and the area of tissue biopsied (mm2). Statistical analysis was performed to identify the characteristics of the CNB that were associated with retention of benign histology on excision. Results: Atypical ductal hyperplasia (ADH) and carcinoma were identified in 6% (3/53) and 8% (4/53) of papillary lesions, respectively, when excised. Clinical and radiographic characteristics did not distinguish the ADH/malignant lesions from benign papillomas. The CNB needle sizes ranged from 9- to 18-gauge (median 14). The number of cores sampled ranged from 3-16 (mean 4.5). Patients with benign excisions had a significantly larger area of tissue sampled by CNB than those found to have ADH/malignant lesions on excision (mean ± SD: 95.6 ± 101.2 vs. 41.7 ± 21.9, respectively, p=0.003). By logistic regression, CNB tissue samples consisting of ≥7 cores, or measuring >96 mm2 in aggregate, had a negative predictive value for ADH/malignancy of 100% (AUC of 0.69 and 0.68, respectively). Conclusions: Although no clinical or radiologic features distinguished benign from pathologically significant papillary lesions, larger sample sizes significantly improved the predictive value of benign histology on CNB. A papilloma sampled by ≥ 7 cores or > 96 mm2 showing benign histology at CNB, retained benign features upon excision. Close surveillance may be a reasonable option for patients whose benign papillomas are generously sampled at the time of CNB.

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