Localization of micro- and intermediate filaments in non-pregnant uterus and placenta of the mink suggests involvement of maternal endothelial cells and periendothelial cells in blood flow regulation

1999 ◽  
Vol 200 (3) ◽  
pp. 253-263 ◽  
Author(s):  
H. Winther ◽  
Rudolf Leiser ◽  
Christiane Pfarrer ◽  
Vibeke Dantzer
Keyword(s):  
Endothelial Cells ◽  
Blood Flow ◽  
Intermediate Filaments ◽  
Flow Regulation ◽  
Pregnant Uterus ◽  
Blood Flow Regulation

scholarly journals Multiple sclerosis disease progression: Contributions from a hypoxia–inflammation cycle

2018 ◽  
Vol 25 (13) ◽  
pp. 1715-1718 ◽  
Author(s):  
Runze Yang ◽  
Jeff F Dunn
Keyword(s):  
Multiple Sclerosis ◽  
Endothelial Cells ◽  
Blood Flow ◽  
Disease Progression ◽  
Flow Regulation ◽  
Blood Flow Regulation ◽  
Multiple Sclerosis Disease ◽  
Interesting Area

Hypoxia has been associated with multiple sclerosis (MS) and is an important area of research. Hypoxia can exacerbate inflammation via the prolylhydroxylase pathway. Inflammation can also trigger hypoxia by damaging mitochondria and endothelial cells to impair blood flow regulation. We hypothesize that there is a “hypoxia–inflammation cycle” in MS which plays an important role in MS disease progression. Therapies that break this cycle may be an interesting area of exploration for treatment of MS.

Relationship of cerebral blood flow regulation to acute mountain sickness.

1989 ◽  
Vol 8 (3) ◽  
pp. 143-148 ◽  
Author(s):  
S M Otis ◽  
M E Rossman ◽  
P A Schneider ◽  
M P Rush ◽  
E B Ringelstein
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Acute Mountain Sickness ◽  
Flow Regulation ◽  
Blood Flow Regulation ◽  
Mountain Sickness ◽  
Relationship Of

scholarly journals Recovery of blood flow regulation in microvascular resistance networks during regeneration of mouse gluteus maximus muscle

2019 ◽  
Vol 597 (5) ◽  
pp. 1401-1417 ◽  
Author(s):  
Charmain A. Fernando ◽  
Aaron M. Pangan ◽  
DDW Cornelison ◽  
Steven S. Segal
Keyword(s):  
Blood Flow ◽  
Gluteus Maximus ◽  
Flow Regulation ◽  
Blood Flow Regulation ◽  
Gluteus Maximus Muscle ◽  
Microvascular Resistance

scholarly journals Peripheral blood flow regulation in response to sympathetic stimulation in individuals with down syndrome

2018 ◽  
Vol 24 (C) ◽  
pp. 16 ◽  
Author(s):  
Thessa I.M. Hilgenkamp ◽  
Sang Ouk Wee ◽  
Elizabeth C. Schroeder ◽  
Tracy Baynard ◽  
Bo Fernhall
Keyword(s):  
Blood Flow ◽  
Down Syndrome ◽  
Peripheral Blood ◽  
Flow Regulation ◽  
Peripheral Blood Flow ◽  
Sympathetic Stimulation ◽  
Blood Flow Regulation

scholarly journals A paradigm shift for local blood flow regulation

2014 ◽  
Vol 116 (6) ◽  
pp. 703-705 ◽  
Author(s):  
Aleksander S. Golub ◽  
Roland N. Pittman
Keyword(s):  
Blood Flow ◽  
Paradigm Shift ◽  
Flow Regulation ◽  
Local Blood Flow ◽  
Blood Flow Regulation

Cerebral vascular autoregulation of blood flow and tissue PO2 in diabetic rats

1985 ◽  
Vol 249 (3) ◽  
pp. H540-H546 ◽  
Author(s):  
M. J. Rubin ◽  
H. G. Bohlen
Keyword(s):  
Blood Flow ◽  
Flow Regulation ◽  
Diabetic Rats ◽  
Adult Rats ◽  
Wall Area ◽  
Normal Limits ◽  
Blood Flow Regulation ◽  
Severe Diabetes ◽  
Tissue Po2 ◽  
Vessel Wall Area

The effect of chronic, severe diabetes mellitus on the morphology, blood flow regulation, and tissue PO2 of the cerebral cortex was evaluated in adult rats. The arterioles of the diabetic animals were enlarged in terms of both lumen diameter and vessel wall area. Although resting blood flow in the diabetic rats was greater than in the normal rats, the autoregulation of cerebral blood flow was very good within an arterial pressure range of 40-150 mmHg, just as in normal rats. The resting tissue PO2 in diabetic rats was 14.9 +/- 0.5 (SEM) compared with 12.7 +/- 0.6 mmHg in normal animals and in both groups remained at or near the resting PO2 at arterial pressures from 40 to 150 mmHg. There was no apparent loss of arterioles on the cortex surface or change in length of individual arterioles in diabetic animals but there was a 20-30% decrease in the number of venules and no change in the length of individual venules. These data indicate that although the arteriolar morphology and number of venules change in the brain during diabetes, physiological function in terms of tissue PO2 and blood flow regulation is maintained within normal limits.

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