The influence of cardiopulmonary bypass priming without FFP on postoperative coagulation and recovery in pediatric patients with cyanotic congenital heart disease

2014 ◽  
Vol 173 (11) ◽  
pp. 1437-1443 ◽  
Author(s):  
Xiaolei Miao ◽  
Jinping Liu ◽  
Mingxia Zhao ◽  
Yongli Cui ◽  
Zhengyi Feng ◽  
...  
2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Amir Mokhtari ◽  
Martin Lewis

Cyanotic congenital heart disease comprises a diverse spectrum of anatomical pathologies. Common to all, however, is chronic hypoxia before these lesions are operated upon when cardiopulmonary bypass is initiated. A range of functional and structural adaptations take place in the chronically hypoxic heart, which, whilst protective in the hypoxic state, are deleterious when the availability of oxygen to the myocardium is suddenly improved. Conventional cardiopulmonary bypass delivers hyperoxic perfusion to the myocardium and is associated with cardiac injury and systemic stress, whilst a normoxic perfusate protects against these insults.


2000 ◽  
Vol 73 (2) ◽  
pp. 173-179 ◽  
Author(s):  
Sven Dittrich ◽  
Katrin Kurschat ◽  
Ingo Dähnert ◽  
Michael Vogel ◽  
Christian Müller ◽  
...  

2012 ◽  
Vol 7 (5) ◽  
pp. 433-440 ◽  
Author(s):  
Sachin Talwar ◽  
Rajesh Khadgawat ◽  
Jandardhan Alamanda Sandeep ◽  
Vishnubhatla Sreenivas ◽  
Shiv Kumar Choudhary ◽  
...  

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