The utility of shear wave elastography and serum biomarkers for diagnosing biliary atresia and predicting clinical outcomes

2021 ◽  
Author(s):  
Yakun Liu ◽  
Chunhui Peng ◽  
Kai Wang ◽  
Dongyang Wu ◽  
Jun Yan ◽  
...  
Keyword(s):  
Biliary Atresia ◽  
Clinical Outcomes ◽  
Shear Wave ◽  
Shear Wave Elastography ◽  
Serum Biomarkers

2D shear wave elastography combined with age and serum biomarkers prior to kasai surgery predicts native liver survival of biliary atresia infants

2020 ◽  
Vol 288 (5) ◽  
pp. 570-580 ◽  
Author(s):  
G. Wang ◽  
H. Chen ◽  
X. Xie ◽  
Q. Cao ◽  
B. Liao ◽  
...  
Keyword(s):  
Biliary Atresia ◽  
Shear Wave ◽  
Shear Wave Elastography ◽  
Serum Biomarkers ◽  
Native Liver ◽  
Native Liver Survival

Spleen stiffness by 2‐D shear wave elastography is the most accurate predictor of high‐risk esophagogastric varices in children with biliary atresia

2019 ◽  
Vol 49 (10) ◽  
pp. 1162-1168 ◽  
Author(s):  
Shinya Yokoyama ◽  
Masatoshi Ishigami ◽  
Takashi Honda ◽  
Teiji Kuzuya ◽  
Yoji Ishizu ◽  
...  
Keyword(s):  
High Risk ◽  
Biliary Atresia ◽  
Shear Wave ◽  
Shear Wave Elastography ◽  
Accurate Predictor ◽  
Esophagogastric Varices ◽  
Spleen Stiffness

Association of shear-wave elastography with clinical outcomes post-liver transplantation

2020 ◽  
Author(s):  
Tom Boeken ◽  
Olivier Lucidarme ◽  
Elsa Mbarki ◽  
Olivier Scatton ◽  
Eric Savier ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Clinical Outcomes ◽  
Shear Wave ◽  
Shear Wave Elastography

Utility of Shear Wave Elastography for Differentiating Biliary Atresia From Infantile Hepatitis Syndrome

2016 ◽  
Vol 35 (7) ◽  
pp. 1475-1479 ◽  
Author(s):  
Xiaoman Wang ◽  
Linxue Qian ◽  
Liqun Jia ◽  
Richard Bellah ◽  
Ning Wang ◽  
...  
Keyword(s):  
Biliary Atresia ◽  
Shear Wave ◽  
Shear Wave Elastography ◽  
Infantile Hepatitis Syndrome

Diagnosis of liver cirrhosis with two-dimensional shear wave elastography in biliary atresia before Kasai portoenterostomy

2021 ◽  
Author(s):  
Cailin Ding ◽  
Zengmeng Wang ◽  
Chunhui Peng ◽  
Wenbo Pang ◽  
Sarah Siyin Tan ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Biliary Atresia ◽  
Shear Wave ◽  
Shear Wave Elastography ◽  
Two Dimensional ◽  
Kasai Portoenterostomy

Shear wave elastography for evaluation of the urgency of liver transplantation in pediatric patients with biliary atresia

2020 ◽  
Vol 24 (8) ◽  
Author(s):  
Li‐hong Gu ◽  
Guang‐xiang Gu ◽  
Hua Fang ◽  
Qiang Xia ◽  
Feng‐hua Li
Keyword(s):  
Liver Transplantation ◽  
Biliary Atresia ◽  
Shear Wave ◽  
Pediatric Patients ◽  
Shear Wave Elastography

Shear wave elastography helps differentiate biliary atresia from other neonatal/infantile liver diseases

2014 ◽  
Vol 45 (3) ◽  
pp. 366-375 ◽  
Author(s):  
Jessica R. Leschied ◽  
Jonathan R. Dillman ◽  
Jacob Bilhartz ◽  
Amer Heider ◽  
Ethan A. Smith ◽  
...  
Keyword(s):  
Biliary Atresia ◽  
Shear Wave ◽  
Liver Diseases ◽  
Shear Wave Elastography

scholarly journals Interconversion of elasticity measurements between two-dimensional shear wave elastography and transient elastography

2018 ◽  
Vol 20 (2) ◽  
pp. 127 ◽  
Author(s):  
Yeun-Yoon Kim ◽  
Myung-Joon Kim ◽  
Hyun Joo Shin ◽  
Haesung Yoon ◽  
Ha Yan Kim ◽  
...  
Keyword(s):  
Biliary Atresia ◽  
Shear Wave ◽  
Transient Elastography ◽  
Intraclass Correlation ◽  
Shear Wave Elastography ◽  
Two Dimensional ◽  
Regression Analyses ◽  
Supersonic Shear Imaging ◽  
Probe Selection ◽  
Elasticity Measurements

Aims: To enable comparison and interconversion of elasticity measurements between two-dimensional (2D) shear wave elastography (SWE) and transient elastography (TE).Materials and methods: Elasticities of three phantoms were measured by 2D SWE (supersonic shear imaging) using four probes and TE using two probes. We performed regression analyses to evaluate correlation between the measurements and phantom elasticities, and make converting equations. In pediatric biliary atresia patients who had stiffness measurements by both 2D SWE and TE within 1-year interval, TE measurements were retrospectively converted into correlating 2D SWE values. We compared the calculated values with 2D SWE measurements by intraclass correlation coefficient.Results: Measurements in phantoms varied according to elastography method and probe selection. However, the measurement by both 2D SWE (R2, 0.974-0.985; p<0.001) and TE (R2, 0.996-0.999; p<0.001) showedsignificant linear correlation with phantom elasticity in all probe settings. From 67 biliary atresia patients (age, 2 months-20 years), agreements between the measured and calculated values were excellent in all 88 examinations within 1-year interval(ρ=0.828; p<0.001) and in 63 examinations within 2-month interval (ρ=0.863, p<0.001). Conclusions: The equations enabledinterconversion of elasticity values among different probes of 2D SWE and TE and provided reliable estimation of elasticityvalues for different probe settings in biliary atresia patients.

scholarly journals Does Supersonic Shear Wave Elastography Help Differentiate Biliary Atresia from Other Causes of Cholestatic Hepatitis in Infants Less than 90 Days Old? Compared with Grey-Scale US

2019 ◽  
Vol 2019 ◽  
pp. 1-10
Author(s):  
Xingxing Duan ◽  
Ya Peng ◽  
Wengang Liu ◽  
Liu Yang ◽  
Jie Zhang
Keyword(s):  
Biliary Atresia ◽  
Young’S Modulus ◽  
Shear Wave ◽  
Sensitivity And Specificity ◽  
Diagnostic Performance ◽  
Young's Modulus ◽  
Shear Wave Elastography ◽  
Cholestatic Hepatitis ◽  
Serial Test ◽  
Grey Scale

Purpose. To investigate the diagnostic performance of shear wave elastography (SWE) for measuring liver stiffness to identify and differentiate biliary atresia (BA) from cholestatic hepatitis in infants younger than 90 days. Methods. A total of 138 infants younger than 90 days with cholestatic hepatitis were examined by SWE. The infants were subclassified into BA and nonbiliary atresia (non-BA) groups. Receiver operating characteristic (ROC) analysis was used to determine the sensitivity and specificity of hepatic Young’s modulus measurements, the ultrasonic findings in the differential diagnosis of suspected BA, and the cut-off value to diagnose BA. Results. In all infants with cholestatic hepatitis, the cut-off value of hepatic Young’s modulus to differentiate the BA group from the non-BA group was 12.35 kPa and the area under the ROC curve (AUC) was 0.937, with a sensitivity of 84.3% and a specificity of 89.7%; nevertheless the AUC of the abnormal gallbladder (AbGB) was 0.940, with a sensitivity of 96.1% and a specificity of 92.0%. In the parallel test, triangular cord (TC) sign combined with AbGB had the best diagnostic performance and the AUC was 0.960, with a sensitivity of 100% and a specificity of 92.0%. In the serial test, SWE combined with AbGB achieved the best diagnostic performance; the AUC was 0.902, the sensitivity and specificity were 80.4% and 100%, respectively. Conclusions. SWE could not only help differentiate BA from cholestatic hepatic diseases but also increase the diagnostic specificity when combined with grey-scale ultrasound in the serial test.

Sign in / Sign up

Export Citation Format

Share Document