young’s modulus
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Materials ◽  
2022 ◽  
Vol 15 (2) ◽  
pp. 632
Author(s):  
Yuri I. Golovin ◽  
Alexander I. Tyurin ◽  
Dmitry Yu. Golovin ◽  
Alexander A. Samodurov ◽  
Sergey M. Matveev ◽  
...  

This paper describes an experimental study of the relationships between thermal diffusivity and mechanical characteristics including Brinell hardness, microhardness, and Young’s modulus of common pine (Pinus sylvestris L.), pedunculate oak (Quercus robur L.), and small-leaf lime (Tilia cordata Mill.) wood. A dependence of Brinell hardness and thermal diffusivity tensor components upon humidity for common pine wood is found. The results of the measurement of Brinell hardness, microhardness, Young’s modulus, and main components of thermal diffusivity tensor for three perpendicular cuts are found to be correlated. It is shown that the mechanical properties correlate better with the ratio of longitude to transversal thermal diffusivity coefficients than with the respective individual absolute values. The mechanical characteristics with the highest correlation with the abovementioned ratio are found to be the ratio of Young’s moduli in longitude and transversal directions. Our technique allows a comparative express assessment of wood mechanical properties by means of a contactless non-destructive measurement of its thermal properties using dynamic thermal imaging instead of laborious and material-consuming destructive mechanical tests.


Nanomaterials ◽  
2022 ◽  
Vol 12 (2) ◽  
pp. 265
Author(s):  
Luis A. Velosa-Moncada ◽  
Jean-Pierre Raskin ◽  
Luz Antonio Aguilera-Cortés ◽  
Francisco López-Huerta ◽  
Agustín L. Herrera-May

Precise prediction of mechanical behavior of thin films at the nanoscale requires techniques that consider size effects and fabrication-related issues. Here, we propose a test methodology to estimate the Young’s modulus of nanometer-thick films using micromachined bilayer cantilevers. The bilayer cantilevers which comprise a well-known reference layer and a tested film deflect due to the relief of the residual stresses generated during the fabrication process. The mechanical relationship between the measured residual stresses and the corresponding deflections was used to characterize the tested film. Residual stresses and deflections were related using analytical and finite element models that consider intrinsic stress gradients and the use of adherence layers. The proposed methodology was applied to low pressure chemical vapor deposited silicon nitride tested films with thicknesses ranging from 46 nm to 288 nm. The estimated Young’s modulus values varying between 213.9 GPa and 288.3 GPa were consistent with nanoindentation and alternative residual stress-driven techniques. In addition, the dependence of the results on the thickness and the intrinsic stress gradient of the materials was confirmed. The proposed methodology is simple and can be used to characterize diverse materials deposited under different fabrication conditions.


Materials ◽  
2022 ◽  
Vol 15 (2) ◽  
pp. 465
Author(s):  
Roberto Scaffaro ◽  
Maria Clara Citarrella ◽  
Emmanuel Fortunato Gulino ◽  
Marco Morreale

In this work, an innovative green composite was produced by adding Hedysarum coronarium (HC) flour to a starch-based biodegradable polymer (Mater-Bi®, MB). The flour was obtained by grinding together stems, leaves and flowers and subsequently sieving it, selecting a fraction from 75 μm to 300 μm. Four formulations have been produced by compression molding (CM) and fused deposition modeling (FDM) by adding 5%, 10%, 15% and 20% of HC to MB. The influence of filler content on the processability was tested, and rheological, morphological and mechanical properties of composites were also assessed. Through CM, it was possible to obtain easily homogeneous samples with all filler amounts. Concerning FDM, 5% and 10% HC-filled composites proved also easily printable. Mechanical results showed filler effectively acted as reinforcement: Young’s modulus and tensile strengths of the composites increased from 74.3 MPa to 236 MPa and from 18.6 MPa to 33.4 MPa, respectively, when 20% of HC was added to the pure matrix. FDM samples, moreover, showed higher mechanical properties if compared with CM ones due to rectilinear infill and fibers orientation. In fact, regarding the 10% HC composites, Young’s modulus of the CM and FDM ones displayed a relative increment of 176% and 224%, respectively.


2022 ◽  
Vol 10 (1) ◽  
pp. 73
Author(s):  
Xi Chen ◽  
Qi Zhang ◽  
Xiang Yuan Zheng ◽  
Yu Lei

In this study, a semi-analytical solution to the dynamic responses of a multilayered transversely isotropic poroelastic seabed under combined wave and current loadings is proposed based on the dynamic stiffness matrix method. This solution is first analytically validated with a single-layered and a two-layered isotropic seabed and then verified against previous experimental results. After that, parametric studies are carried out to probe the effects of the soil’s anisotropic characteristics and the effects of ocean waves and currents on the dynamic responses and the maximum liquefaction depth. The results show that the dynamic responses of a transversely isotropic seabed are more sensitive to the ratio of the soil’s vertical Young’s modulus to horizontal Young’s modulus (Ev/Eh) and the ratio of the vertical shear modulus to Ev (Gv/Ev) than to the vertical-to-horizontal ratio of the permeability coefficient (Kv/Kh). A lower degree of quasi-saturation, higher porosity, a shorter wave period, and a following current all result in a greater maximum liquefaction depth. Moreover, it is revealed that the maximum liquefaction depth of a transversely isotropic seabed would be underestimated under the isotropic assumption. Furthermore, unlike the behavior of an isotropic seabed, the transversely isotropic seabed tends to liquefy when fully saturated in nonlinear waves. This result supplements and reinforces the conclusions determined in previous studies. This work affirms that it is necessary for offshore engineering to consider the transversely isotropic characteristics of the seabed for bottom-fixed and subsea offshore structures.


Author(s):  
Takuya Ishimoto ◽  
Mitsuru Saito ◽  
Ryosuke Ozasa ◽  
Yoshihiro Matsumoto ◽  
Takayoshi Nakano

AbstractBone material quality is important for evaluating the mechanical integrity of diseased and/or medically treated bones. However, compared to the knowledge accumulated regarding changes in bone mass, our understanding of the quality of bone material is lacking. In this study, we clarified the changes in bone material quality mainly characterized by the preferential orientation of the apatite c-axis associated with estrogen deficiency-induced osteoporosis, and their prevention using ibandronate (IBN), a nitrogen-containing bisphosphonate. IBN effectively prevented bone loss and degradation of whole bone strength in a dose-dependent manner. The estrogen-deficient condition abnormally increased the degree of apatite orientation along the craniocaudal axis in which principal stress is applied; IBN at higher doses played a role in maintaining the normal orientation of apatite but not at lower doses. The bone size-independent Young's modulus along the craniocaudal axis of the anterior cortical shell of the vertebra showed a significant and positive correlation with apatite orientation; therefore, the craniocaudal Young’s modulus abnormally increased under estrogen-deficient conditions, despite a significant decrease in volumetric bone mineral density. However, the abnormal increase in craniocaudal Young's modulus did not compensate for the degradation of whole bone mechanical properties due to the bone loss. In conclusion, it was clarified that changes in the material quality, which are hidden in bone mass evaluation, occur with estrogen deficiency-induced osteoporosis and IBN treatment. Here, IBN was shown to be a beneficial drug that suppresses abnormal changes in bone mechanical integrity caused by estrogen deficiency at both the whole bone and material levels.


Author(s):  
Bo Zhang ◽  
Lihui Zhang ◽  
Na Yang ◽  
Xuewen Zhao ◽  
Chengxiang Chen ◽  
...  

Cancers ◽  
2022 ◽  
Vol 14 (1) ◽  
pp. 259
Author(s):  
Massimo Alfano ◽  
Irene Locatelli ◽  
Cristina D’Arrigo ◽  
Marco Mora ◽  
Giovanni Vozzi ◽  
...  

Purpose: The biochemical composition and architecture of the extracellular matrix (ECM) is known to condition development and invasiveness of neoplasms. To clarify this point, we analyzed ECM stiffness, collagen cross-linking and anisotropy in lymph nodes (LN) of Hodgkin lymphomas (HL), follicular lymphomas (FL) and diffuse large B-cell lymphomas (DLBCL), compared with non-neoplastic LN (LDN). Methods and Results: We found increased elastic (Young’s) modulus in HL and advanced FL (grade 3A) over LDN, FL grade 1–2 and DLBCL. Digital imaging evidenced larger stromal areas in HL, where increased collagen cross-linking was found; in turn, architectural modifications were documented in FL3A by scanning electron microscopy and enhanced anisotropy by polarized light microscopy. Interestingly, HL expressed high levels of lysyl oxidase (LOX), an enzyme responsible for collagen cross-linking. Using gelatin scaffolds fabricated with a low elastic modulus, comparable to that of non-neoplastic tissues, we demonstrated that HL LN-derived mesenchymal stromal cells and HL cells increased the Young’s modulus of the extracellular microenvironment through the expression of LOX. Indeed, LOX inhibition by β-aminopropionitrile prevented the gelatin stiffness increase. Conclusions: These data indicate that different mechanical, topographical and/or architectural modifications of ECM are detectable in human lymphomas and are related to their histotype and grading.


Author(s):  
Dornaz Milani ◽  
Siamak Khoramymehr ◽  
Behrouz Vasaghi-Gharamaleki

Background: In most communities, the risk of developing breast cancer is increasing. By affecting the cyclooxygenase 1 and 2 (COX-1 and COX-2) enzymes and actin filaments, acetylsalicylic acid (Aspirin) has been shown to reduce the risk of breast cancer and prevent cell migration in both laboratory and clinical studies. Methods: The purpose of this study is to determine the mechanical properties of normal and cancerous breast tissue cells, as well as the short-term effect of aspirin on cancer cells. To this end, the mechanical properties and deformation of three cell types were investigated: healthy MCF-10 breast cells, MCF-7 breast cancer cells, and MCF-7 breast cancer cells treated with a 5 µM aspirin solution. Atomic Force Microscopy (AFM) was used to determine the mechanical properties of the cells. Cell deformation was analyzed in all groups, and Young's modulus was calculated using the Hertz model. Result: According to the obtained data, cancer cells deformed at a rate half that of healthy cells. Nonetheless, when aspirin was used, cancer cells deformed similarly to healthy cells. Additionally, healthy cells' Young's modulus was calculated to be approximately three times that of cancer cells, which was placed closer to that of healthy cells by adding aspirin to Young's modulus. Conclusion: Cell strength appears to have increased due to aspirin's intervention on actin filaments and cytoskeletons, and the mechanical properties of breast cancer cells have become more similar to those of normal cells. The likelihood of cell migration and metastasis decreases as cell strength increases.


2022 ◽  
Vol 12 ◽  
Author(s):  
Esthevan Machado ◽  
Fábio Juner Lanferdini ◽  
Edson Soares da Silva ◽  
Jeam Marcel Geremia ◽  
Francesca Chaida Sonda ◽  
...  

Purpose: This study aimed to determine whether triceps surae’s muscle architecture and Achilles tendon parameters are related to running metabolic cost (C) in trained long-distance runners.Methods: Seventeen trained male recreational long-distance runners (mean age = 34 years) participated in this study. C was measured during submaximal steady-state running (5 min) at 12 and 16 km h–1 on a treadmill. Ultrasound was used to determine the gastrocnemius medialis (GM), gastrocnemius lateralis (GL), and soleus (SO) muscle architecture, including fascicle length (FL) and pennation angle (PA), and the Achilles tendon cross-sectional area (CSA), resting length and elongation as a function of plantar flexion torque during maximal voluntary plantar flexion. Achilles tendon mechanical (force, elongation, and stiffness) and material (stress, strain, and Young’s modulus) properties were determined. Stepwise multiple linear regressions were used to determine the relationship between independent variables (tendon resting length, CSA, force, elongation, stiffness, stress, strain, Young’s modulus, and FL and PA of triceps surae muscles) and C (J kg–1m–1) at 12 and 16 km h–1.Results: SO PA and Achilles tendon CSA were negatively associated with C (r2 = 0.69; p < 0.001) at 12 km h–1, whereas SO PA was negatively and Achilles tendon stress was positively associated with C (r2 = 0.63; p = 0.001) at 16 km h–1, respectively. Our results presented a small power, and the multiple linear regression’s cause-effect relation was limited due to the low sample size.Conclusion: For a given muscle length, greater SO PA, probably related to short muscle fibers and to a large physiological cross-sectional area, may be beneficial to C. Larger Achilles tendon CSA may determine a better force distribution per tendon area, thereby reducing tendon stress and C at submaximal speeds (12 and 16 km h–1). Furthermore, Achilles tendon morphological and mechanical properties (CSA, stress, and Young’s modulus) and triceps surae muscle architecture (GM PA, GM FL, SO PA, and SO FL) presented large correlations with C.


Author(s):  
He Ren ◽  
Eunice Cunha ◽  
Zheling Li ◽  
Lei Wang ◽  
Ian A. Kinloch ◽  
...  

AbstractSilane-functionalized graphene nanoplatelets (GNPs) were prepared using a newly developed approach based upon a simple two-step strategy. The effect of their dispersion and interfacial bonding on the mechanical properties and thermal conductivity of reinforced silicone rubber (SR) was investigated. It was found by Raman mapping that the silane-functionalized GNPs could be dispersed uniformly into the SR matrix, leading to an increase of up to 25% in Young’s modulus at only 2 parts per hundred rubber (phr) loading and a considerable enhancement of up to 150% in the thermal conductivity at 5-phr loading. Both the Young’s modulus and thermal conductivity experimental results were found to be in agreement with the values predicted using theoretical models. Graphical abstract


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