Storage and secretion of Ag-Aper14, a novel peritrophic matrix protein, and Ag-Muc1 from the mosquito Anopheles gambiae

2005 ◽  
Vol 320 (1) ◽  
pp. 175-185 ◽  
Author(s):  
M. Devenport ◽  
H. Fujioka ◽  
M. Donnelly-Doman ◽  
Z. Shen ◽  
M. Jacobs-Lorena
Keyword(s):  
Anopheles Gambiae ◽  
Matrix Protein ◽  
Peritrophic Matrix ◽  
Mosquito Anopheles Gambiae

scholarly journals Identifying and Characterizing a Novel Peritrophic Matrix Protein (MdPM-17) Associated With Antibacterial Response From the Housefly, Musca domestica (Diptera: Muscidae)

2020 ◽  
Vol 20 (6) ◽  
Author(s):  
Yu Wang ◽  
Jinzhi Cheng ◽  
Man Luo ◽  
Jianwei Wu ◽  
Guo Guo
Keyword(s):  
Amino Acid ◽  
Antimicrobial Peptide ◽  
Musca Domestica ◽  
Matrix Protein ◽  
Binding Capacity ◽  
Malpighian Tubule ◽  
Peritrophic Membrane ◽  
Distribution Analysis ◽  
Peritrophic Matrix ◽  
Amino Acid Residues

Abstract Peritrophic matrix/membrane (PM) critically prevents the midgut of insects from external invasion by microbes. The proteins in the peritrophic membrane are its major structural components. Additionally, they determine the formation and function of this membrane. However, the role of PM proteins in immune regulation is unclear. Herein, we isolated a novel PM protein (MdPM-17) from Musca domestica larvae. Further, the function of MdPM-17 in regulating host innate immunity was identified. Results showed that the cDNA of MdPM-17 full is 635 bp in length. Moreover, it consists of a 477-bp open reading frame encoding 158 amino acid residues. These amino acid residues are composed of two Chitin-binding type-2 domain (ChtBD2) and 19 amino acids as a signal peptide. Moreover, tissue distribution analysis indicates that MdPM-17 was enriched expressed in midgut, and moderate levels in the fat body, foregut, and malpighian tubule. Notably, MdPM-17 recombinant protein showed high chitin-binding capacity, thus belongs to the Class III PM protein group. MdPM-17 protein silencing via RNA interference resulted in the expression of antimicrobial peptide (defensin, cecropins, and diptericin) genes, and this occurred after oral inoculation with exogenous microbes Escherichia coli (Enterobacteriales:Enterobacteriaceae), Staphylococcus aureus (Bacillales:Staphylococcaceae), and Candida albicans (Endomycetales:Saccharomycetaceae)). Therefore, all the antimicrobial peptide (AMP) gene expression levels are high in MdPM-17-depleted larvae during microbial infection compared to controls. Consequently, these findings indicate that MdPM-17 protein is associated with the antibacterial response from the housefly.

scholarly journals A cell surface mucin specifically expressed in the midgut of the malaria mosquito Anopheles gambiae

1999 ◽  
Vol 96 (10) ◽  
pp. 5610-5615 ◽  
Author(s):  
Z. Shen ◽  
G. Dimopoulos ◽  
F. C. Kafatos ◽  
M. Jacobs-Lorena
Keyword(s):  
Cell Surface ◽  
Anopheles Gambiae ◽  
Malaria Mosquito ◽  
Mosquito Anopheles Gambiae ◽  
A Cell

scholarly journals Low-resolution genome map of the malaria mosquito Anopheles gambiae.

1991 ◽  
Vol 88 (24) ◽  
pp. 11187-11191 ◽  
Author(s):  
L. B. Zheng ◽  
R. D. Saunders ◽  
D. Fortini ◽  
A. della Torre ◽  
M. Coluzzi ◽  
...  
Keyword(s):  
Anopheles Gambiae ◽  
Malaria Mosquito ◽  
Low Resolution ◽  
Genome Map ◽  
Mosquito Anopheles Gambiae

Q: a new retrotransposon from the mosquito Anopheles gambiae

2007 ◽  
Vol 3 (1) ◽  
pp. 49-56 ◽  
Author(s):  
N. J. Besansky ◽  
J. A. Bedell ◽  
O. Mukabayire
Keyword(s):  
Anopheles Gambiae ◽  
Mosquito Anopheles Gambiae

scholarly journals Odorant reception in the malaria mosquito Anopheles gambiae

Nature ◽  
2010 ◽  
Vol 464 (7285) ◽  
pp. 66-71 ◽  
Author(s):  
Allison F. Carey ◽  
Guirong Wang ◽  
Chih-Ying Su ◽  
Laurence J. Zwiebel ◽  
John R. Carlson
Keyword(s):  
Anopheles Gambiae ◽  
Malaria Mosquito ◽  
Mosquito Anopheles Gambiae

scholarly journals Transgenic Expression of the Anti-parasitic Factor TEP1 in the Malaria Mosquito Anopheles gambiae

2017 ◽  
Vol 13 (1) ◽  
pp. e1006113 ◽  
Author(s):  
Gloria Volohonsky ◽  
Ann-Katrin Hopp ◽  
Mélanie Saenger ◽  
Julien Soichot ◽  
Heidi Scholze ◽  
...  
Keyword(s):  
Anopheles Gambiae ◽  
Malaria Mosquito ◽  
Transgenic Expression ◽  
Mosquito Anopheles Gambiae

scholarly journals Antennal-Expressed Ammonium Transporters in the Malaria Vector Mosquito Anopheles gambiae

PLoS ONE ◽  
2014 ◽  
Vol 9 (10) ◽  
pp. e111858 ◽  
Author(s):  
R. Jason Pitts ◽  
Stephen L. Derryberry ◽  
Fadi E. Pulous ◽  
Laurence J. Zwiebel
Keyword(s):  
Anopheles Gambiae ◽  
Malaria Vector ◽  
Ammonium Transporters ◽  
Vector Mosquito ◽  
Mosquito Anopheles Gambiae
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