Dynamic content changes of cordycepin and adenosine and transcriptome in Cordyceps kyushuensis Kob at different fermentation stages

Author(s):  
Junyu Zhang ◽  
Tongtong Jian ◽  
Yu Zhang ◽  
Guoying Zhang ◽  
Jianya Ling
Keyword(s):  
2000 ◽  
Vol 29 (1) ◽  
pp. 26-31 ◽  
Author(s):  
Alexandros Labrinidis ◽  
Nick Roussopoulos
Keyword(s):  

2014 ◽  
Vol 29 (4) ◽  
pp. 312-326 ◽  
Author(s):  
Alan R Dennis ◽  
Binny M Samuel ◽  
Kelly McNamara

Information system maintenance is an important aspect of information system development, especially in systems that provide dynamic content, such as Web-based systems and Knowledge Management Systems (KMS). Design for Maintenance (DFM) is an approach that argues that maintenance effort should be considered during the design of information systems in addition to the usual system design considerations. This research examines how the design of links among knowledge documents in a KMS affects both their maintenance and use. We argue that providing links among knowledge documents increases the cost of maintenance because when a document changes, the documents that link to and from that document are more likely to need changes. At the same, linking knowledge documents makes it easier to locate useful knowledge and thus increases use. We examine this tension between use and maintenance using 10 years of data from a well-established KMS. Our results indicate that as the number of links among documents increases, both maintenance effort and use for these documents increase. Our analyses suggest two DFM principles for dynamic content in practice. First, knowledge coupling (i.e., linking) to documents internal to the KMS rather than sources external to the KMS better balances maintenance effort and use. Second, designing small, knowledge cohesive documents (e.g., 250-350 words) leads to the best balance between maintenance effort and use.


2004 ◽  
Vol 19 (10) ◽  
pp. 1609-1638 ◽  
Author(s):  
ADRIAN P. GENTLE ◽  
NATHAN D. GEORGE ◽  
ARKADY KHEYFETS ◽  
WARNER A. MILLER

We compare different treatments of the constraints in canonical quantum gravity. The standard approach on the superspace of 3-geometries treats the constraints as the sole carriers of the dynamic content of the theory, thus rendering the traditional dynamical equations obsolete. Quantization of the constraints in both the Dirac and ADM square root Hamiltonian approaches leads to the well known problems of time evolution. These problems of time are of both an interpretational and technical nature. In contrast, the geometrodynamic quantization procedure on the superspace of the true dynamical variables separates the issues of quantization from the enforcement of the constraints. The resulting theory takes into account states that are off-shell with respect to the constraints, and thus avoids the problems of time. We develop, for the first time, the geometrodynamic quantization formalism in a general setting and show that it retains all essential features previously illustrated in the context of homogeneous cosmologies.


2021 ◽  
Author(s):  
G. Le ◽  
S. Ferdousi ◽  
A. Marotta ◽  
S. Xu ◽  
Y. Hirota ◽  
...  

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