Safety and feasibility of laparoscopic liver resection for hepatocellular carcinoma with clinically significant portal hypertension: a propensity score-matched study

2020 ◽  
Author(s):  
Junhao Zheng ◽  
Xu Feng ◽  
Yuelong Liang ◽  
Jingwei Cai ◽  
Zhaoqi Shi ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Portal Hypertension ◽  
Liver Resection ◽  
Propensity Score ◽  
Laparoscopic Liver Resection ◽  
Clinically Significant ◽  
Matched Study

Laparoscopic and open liver resection for hepatocellular carcinoma with Child–Pugh B cirrhosis: multicentre propensity score-matched study

2021 ◽  
Author(s):  
R I Troisi ◽  
G Berardi ◽  
Z Morise ◽  
F Cipriani ◽  
S Ariizumi ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Portal Hypertension ◽  
Survival Rate ◽  
Liver Resection ◽  
Propensity Score ◽  
Laparoscopic Liver Resection ◽  
Laparoscopic Resection ◽  
Postoperative Mortality ◽  
Open Approach ◽  
Liver Resections

Abstract Background Laparoscopic liver resection for hepatocellular carcinoma (HCC) in Child–Pugh A cirrhosis has been demonstrated as beneficial. However, the role of laparoscopy in Child–Pugh B cirrhosis is undetermined. The aim of this retrospective cohort study was to compare open and laparoscopic resection for HCC with Child–Pugh B cirrhosis. Methods Data on liver resections were gathered from 17 centres. A 1 : 1 propensity score matching was performed according to 17 predefined variables. Results Of 382 available liver resections, 100 laparoscopic and 100 open resections were matched and analysed. The 90-day postoperative mortality rate was similar in open and laparoscopic groups (4.0 versus 2.0 per cent respectively; P = 0.687). Laparoscopy was associated with lower blood loss (median 110 ml versus 400 ml in the open group; P = 0.004), less morbidity (38.0 versus 51.0 per cent respectively; P = 0.041) and fewer major complications (7.0 versus 21.0 per cent; P = 0.010), and ascites was lower on postoperative days 1, 3 and 5. For laparoscopic resections, patients with portal hypertension developed more complications than those without (26 versus 12 per cent respectively; P = 0.002), and patients with a Child–Pugh B9 score had higher morbidity rates than those with B8 and B7 (7 of 8, 10 of 16 and 21 of 76 respectively; P < 0.001). Median hospital stay was 7.5 (range 2–243) days for laparoscopic liver resection and 18 (3–104) days for the open approach (P = 0.058). The 5-year overall survival rate was 47 per cent for open and 65 per cent for laparoscopic resection (P = 0.142). The 5-year disease-free survival rate was 32 and 37 per cent respectively (P = 0.742). Conclusion Patients without preoperative portal hypertension and Child–Pugh B7 cirrhosis may benefit most from laparoscopic liver surgery.

Benefits of laparoscopic liver resection in patients with hepatocellular carcinoma and portal hypertension: a case-matched study

2017 ◽  
Vol 32 (5) ◽  
pp. 2345-2354 ◽  
Author(s):  
Víctor Molina ◽  
Jaime Sampson-Dávila ◽  
Joana Ferrer ◽  
Constantino Fondevila ◽  
Rafael Díaz del Gobbo ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Portal Hypertension ◽  
Liver Resection ◽  
Laparoscopic Liver Resection ◽  
Matched Study

Laparoscopic versus open liver resection for hepatocellular carcinoma: Case-matched study with propensity score matching

2015 ◽  
Vol 63 (3) ◽  
pp. 643-650 ◽  
Author(s):  
Ho-Seong Han ◽  
Ahmed Shehta ◽  
Soyeon Ahn ◽  
Yoo-Seok Yoon ◽  
Jai Young Cho ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Resection ◽  
Propensity Score ◽  
Propensity Score Matching ◽  
Open Liver Resection ◽  
Matched Study

Short- and Long-term Outcomes after Robotic and Laparoscopic Liver Resection for Malignancies: A Propensity Score-Matched Study

2019 ◽  
Vol 43 (6) ◽  
pp. 1594-1603 ◽  
Author(s):  
Chetana Lim ◽  
Chady Salloum ◽  
Antonella Tudisco ◽  
Claudio Ricci ◽  
Michael Osseis ◽  
...  
Keyword(s):  
Liver Resection ◽  
Propensity Score ◽  
Laparoscopic Liver Resection ◽  
Long Term Outcomes ◽  
Short And Long Term ◽  
Matched Study

Laparoscopic Liver Resection for Hepatocellular Carcinoma in Child–Pugh A Patients With and Without Portal Hypertension: A Multicentre Study

2020 ◽  
Vol 44 (11) ◽  
pp. 3915-3922
Author(s):  
Margarida Casellas-Robert ◽  
Chetana Lim ◽  
Santiago Lopez-Ben ◽  
Laura Lladó ◽  
Chady Salloum ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Portal Hypertension ◽  
Liver Resection ◽  
Multicentre Study ◽  
Laparoscopic Liver Resection

scholarly journals Benefits of laparoscopic liver resection in patients with Hepatocellular carcinoma and portal hypertension: a casematched study

HPB ◽  
2019 ◽  
Vol 21 ◽  
pp. S981
Author(s):  
V. Molina ◽  
J. Sampson ◽  
C. Muñoz ◽  
J. Ferrer ◽  
S. Sanchez-Cabus ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Portal Hypertension ◽  
Liver Resection ◽  
Laparoscopic Liver Resection

scholarly journals Benefits of laparoscopic liver resection in patients with Hepatocellular carcinoma and portal hypertension: A casematched study

HPB ◽  
2019 ◽  
Vol 21 ◽  
pp. S579
Author(s):  
V. Molina ◽  
J. Sampson ◽  
C. Muñoz ◽  
J. Ferrer ◽  
S. Sanchez-Cabus ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Portal Hypertension ◽  
Liver Resection ◽  
Laparoscopic Liver Resection
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