scholarly journals Enhancing evaluation of sarcopenia in patients with non-small cell lung cancer (NSCLC) by assessing skeletal muscle index (SMI) at the first lumbar (L1) level on routine chest computed tomography (CT)

2018 ◽  
Vol 26 (7) ◽  
pp. 2353-2359 ◽  
Author(s):  
Alejandro Recio-Boiles ◽  
Jose N. Galeas ◽  
Bernard Goldwasser ◽  
Karla Sanchez ◽  
Louise M. W. Man ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Lung Cancer ◽  
Skeletal Muscle ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
Skeletal Muscle Index ◽  
Chest Computed Tomography ◽  
Routine Chest

scholarly journals P2.03b-060 Baseline Skeletal Muscle Index (SMI) Values Are Associated with Biomarkers of Insulin Resistance in Stage IV Non-Small Cell Lung Cancer

2017 ◽  
Vol 12 (1) ◽  
pp. S971-S972
Author(s):  
Marta Batus ◽  
Samantha Kerns ◽  
Selina Savidine ◽  
Cristina Fhied ◽  
Sanjib Basu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Insulin Resistance ◽  
Skeletal Muscle ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Stage Iv ◽  
Small Cell ◽  
Small Cell Lung ◽  
Skeletal Muscle Index

scholarly journals Cachexia Index in Advanced Non-Small-Cell Lung Cancer Patients

2015 ◽  
Vol 9 ◽  
pp. CMO.S30891 ◽  
Author(s):  
Syed Hasan Raza Jafri ◽  
Carlos Previgliano ◽  
Keerti Khandelwal ◽  
Runhua Shi
Keyword(s):  
Lung Cancer ◽  
Skeletal Muscle ◽  
Small Cell Lung Cancer ◽  
Cancer Patients ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Stage I ◽  
Stage Ii ◽  
Small Cell Lung ◽  
Skeletal Muscle Index

Introduction Cancer cachexia affects many advanced non-small-cell lung cancer (NSCLC) patients. Cachexia index (CXI) was developed to assess the degree of cachexia in these patients. Methods Patients with metastatic NSCLC diagnosed between January 1, 2000, and June 30, 2011, at our institution were retrospectively studied. Abdominal computed tomography scans done within 1 month of diagnosis were reviewed to estimate skeletal muscle area (SMA) and skeletal muscle index (SMI) at the L3 level. CXI was developed as follows: [Formula: see text] where SMI is the skeletal muscle index, Alb is the serum albumin, and NLR is the NLR neutrophil-to-lymphocyte ratio. Progression-free survival (PFS) and overall survival (OS) were estimated using the Kaplan–Meier method. Survival among various factors was calculated using the log-rank test. Multivariate Cox regression was used to perform survival analysis in order to estimate the effects of various factors. Results Patients were divided into two groups around the median into stage I cachexia (CXI ≥35, n = 56) and stage II cachexia (CXI <35, n = 56). Groups did not differ in age, gender, ethnicity, or histology of cancer. Patients with stage II cachexia had significantly worse PFS (2.45 vs 5.43 months, P < 0.0001) and OS (3.45 vs 8.8 months, P = 0.0001) than those with stage I cachexia. On multivariate analysis adjusting for gender, race, and histology, patients with stage II cachexia were found to have worse PFS (hazard ratio [HR] 1.94, 95% confidence interval [CI] 1.27–2.95) and OS (HR 1.53, 95% CI 1.0009–2.34). Conclusion The CXI is a novel index for estimating cachexia that also correlates with prognosis in both men and women with advanced NSCLC.

Association of biomarkers of insulin resistance and inflammation with skeletal muscle index (SMI) in stage IV non-small cell lung cancer (NSCLC).

2016 ◽  
Vol 34 (15_suppl) ◽  
pp. 10013-10013
Author(s):  
Marta Batus ◽  
Samantha Kerns ◽  
Selina Sayidine ◽  
Cristina L. Fhied ◽  
Sanjib Basu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Insulin Resistance ◽  
Skeletal Muscle ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Stage Iv ◽  
Small Cell ◽  
Small Cell Lung ◽  
Skeletal Muscle Index

scholarly journals P07.07 Computed Tomography of Lymph Nodes to Predict Occult pN2 Disease in Non-Small-Cell Lung Cancer

2021 ◽  
Vol 16 (3) ◽  
pp. S280
Author(s):  
H. Onozawa ◽  
D. Nemoto ◽  
J. Miura ◽  
D. Eriguchi ◽  
H. Adachi ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Lung Cancer ◽  
Lymph Nodes ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung

Comparison of bronchoscopy and computed tomography-guided needle biopsy for re-biopsy in non-small cell lung cancer patients

2021 ◽  
Vol 59 (2) ◽  
pp. 240-246
Author(s):  
Hirohisa Kano ◽  
Toshio Kubo ◽  
Kiichiro Ninomiya ◽  
Eiki Ichihara ◽  
Kadoaki Ohashi ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cancer Patients ◽  
Cell Lung Cancer ◽  
Needle Biopsy ◽  
Small Cell ◽  
Small Cell Lung ◽  
Lung Cancer Patients
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