Trajectories of glycaemia following acute pancreatitis: a prospective longitudinal cohort study with 24 months follow-up

2020 ◽  
Vol 55 (8) ◽  
pp. 775-788 ◽  
Author(s):  
Sakina Huseni Bharmal ◽  
Jaelim Cho ◽  
Gisselle Charlott Alarcon Ramos ◽  
Juyeon Ko ◽  
Charlotte Elizabeth Stuart ◽  
...  
2015 ◽  
Vol 172 (6) ◽  
pp. 1646-1650 ◽  
Author(s):  
E. Livingstone ◽  
T.K. Eigentler ◽  
C. Windemuth-Kieselbach ◽  
A. Hauschild ◽  
R. Rompel ◽  
...  

2021 ◽  
Author(s):  
Fernando D. Correia ◽  
Maria Molinos ◽  
Carlos Neves ◽  
Dora Janela ◽  
Diana Carvalho ◽  
...  

BACKGROUND Ankle sprains are one of the most prevalent soft-tissue injuries worldwide. Physical therapy, and especially progressive exercise, has proven effective in improving function, while preventing recurrence. OBJECTIVE We aimed to present the results of a fully remote and digitally guided rehabilitation program for acute ankle sprains. METHODS Prospective, longitudinal cohort study of individuals referred for digital rehabilitation therapy for ankle sprain, and eligible for workers’ compensation. Primary endpoints were the change in self-reported Numerical Pain Rating Scale (NPRS) and Foot and Ankle Ability Measure - activities of daily living (FAAM-ADL) and -sports (FAAM-Sports). Participants were assessed at baseline, end-of-program and 6-months after program completion. Secondary outcomes included digital therapy dosage, pain and fatigue during sessions, and satisfaction. RESULTS Ninety-three patients (89.4%) completed the program and seventy-nine were available for follow-up (76.0%). Changes in the primary outcomes between baseline and the 6-months follow-up were both statistically significant (P<.001) and clinically meaningful: mean difference of -2.72 points (95% CI -3-31 to -2.13) in NPRS (49.8% reduction), 21.7 points (95% CI 17.13 to 26.27) in FAAM-ADL (41.1% increase) and 37.8 points (95% CI 30.45 to 45.15) in FAAM-Sports (151.8% increase). Longer waiting periods between accident date and treatment initiation were found to negatively impact functional status at baseline and end-of-program, triggering extended program duration. Total training volume (12.5 h, sd=10.5) was similar to other interventions for ankle sprains, but dosage per week was much higher (2.4 h per week, sd=0.87). Mean patient satisfaction score was 8.8/10 (sd=1.57). Among program completers, 83.9% attained full recovery and were discharged with no residual disability. CONCLUSIONS Being far less demanding in terms of human resources, the digital program presented constitutes a viable, clinically effective and convenient solution for ankle sprains rehabilitation, particularly in pandemic times. This is the first study presenting a fully remote home-based rehabilitation program for acute ankle sprains, with patients achieving sustained long-term results, comparable to those published for face-to-face interventions. CLINICALTRIAL NCT04819022; https://clinicaltrials.gov/ct2/show/NCT04819022


Author(s):  
Margareta Møkleby ◽  
Britt Øverland

AbstractContinuous positive airway pressure (CPAP) is an efficient treatment for obstructive sleep apnea (OSA). Reports of long-term usage vary, as do the factors that predict long-term usage. The aim of this study was to explore long-term CPAP usage and identify potential predictors. This prospective longitudinal cohort study included all patients referred to an outpatient clinic for CPAP treatment during an eight-month period. Clinical data were collected at baseline. Follow-ups were scheduled after one week, three months and two years. Use data were downloaded from the CPAP device at each follow-up. Of 163 included patients, 112 were available for long-term follow-up 2–4 years after starting CPAP, and use data were downloaded for 99 patients. Median duration of CPAP use was 6 h/night (IQR 4.2–7.1). The only significant variable predicting long-term usage was usage at three months. Nearly half (43%) of the patients needed extra consultations beyond the standard treatment plan. Most patients (69%) did not contact the clinic for their recommended two-year follow-up but were instead called into the clinic specifically for the study. There was no significant difference in long-term CPAP usage between patients who initiated contact themselves and those who were called in and would otherwise have been lost for follow-up. Most patients adhere well to CPAP in the long term, although many need extra follow-up. Patients lost for follow-up should not necessarily be considered non-adherent as their reason for not attending could be that they are managing treatment well on their own.


Kinesiology ◽  
2021 ◽  
Vol 53 (2) ◽  
pp. 336-342
Author(s):  
Pedro Ángel Latorre Román ◽  
Juan Antonio Párraga Montilla ◽  
Jeśús Salas Sánchez ◽  
Pedro José Consuegra González

Rearfoot strike (RFS) in children running produces impact forces that give rise to a transient stress wave traveling through the body. It could contribute to the development of injuries. The purpose of this study was to determine RFS prevalence during childhood while running at a self-selected velocity in a prospective longitudinal cohort study. A total of 175 children (68 girls), aged 6 to 14 years, participated in this study. The sample was divided into three age groups (age in 2016): 6-8 years, 9-11 years, and 12-14 years which were analysed three years later (2019). 2D video-based was used to record the RFS Taking into account all samples, in the jogging trial the prevalence of RFS (an average of both feet) was 86.9% in 2016 and 94.7% three years later; in the running trial the prevalence was 82.6 and 94.4%, respectively. In all samples a significant increase of RFS prevalence was found in both the jogging and running trials for both feet over three years (jogging, left foot, p=.011, right foot, p=.023; running, left foot, p=.001, right foot, p&lt;.001). In girls, there were no significant differences in any conditions. In boys, a significant increase of RFS prevalence was found after three years in both feet (p&lt;.01) in the running trial. This study shows that RFS prevalence in children increases with age and the results may be used to characterize typical running development in children population.


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