scholarly journals Positive relationship between bone mineral density and low back pain in middle-aged women

2003 ◽  
Vol 12 (6) ◽  
pp. 596-601 ◽  
Author(s):  
Takashi Manabe ◽  
Shin-ichiro Takasugi ◽  
Yukihide Iwamoto
2021 ◽  
pp. ijgc-2020-002290
Author(s):  
Divyesh Kumar ◽  
Raviteja Miriyala ◽  
Bhavana Rai ◽  
Pooja Bansal ◽  
Arun S Oinam ◽  
...  

ObjectiveTo prospectively analyze the effect of three-dimensional chemoradiation on the bone mineral density of pelvic bones and its association with low back pain and disability in patients with locally advanced cervical cancer.MethodsIn biopsy proven locally advanced cervical cancer patients, bone mineral density and T scores for lumbar vertebrae 5, dorsal thoracic vertebrae 12, and T scores for the femoral neck were analyzed. Low back pain was scored using the visual analog scale while disability scoring was done using the Oswestry low back pain disability scale. Furthermore, a subgroup analysis for patients (classified according to menopausal status) was performed.ResultsIn total, 106 patients were analyzed. A statistically significant decline in mean bone mineral density was observed at all three sites (vertebrae 5 and 12, and the femoral neck) post-chemoradiation therapy compared with pretreatment bone mineral density (0.671 vs 0.828, −2.083 vs −1.531, −2.503 vs −1.626; all p<0.001). Similarly, in subgroup analyses, at all three sites, pre-menopausal patients showed a statistically significant association (0.876 vs 0.697, −1.203 vs −0.2.761, –1.403 vs −2.232; all p<0.001) while a non-significant association was observed for post-menopausal patients at vertebrae 12 (−1.707 vs −1.719; p=0.09) with a statistically significant association at vertebrae 5 and the femoral neck (0.803 vs 0.656, –1.746 vs −2.648; p<0.01). Although statistically significant low back pain and disability scores were observed overall and irrespective of menopausal status, no correlation between bone mineral density and low back pain and disability was observed.ConclusionPelvic bone mineral density decreases significantly after chemoradiation, irrespective of menopausal status. However, no correlation with low back pain and disability was observed. Pelvic bone mineral density analysis should be considered before chemoradiation in cervical cancer.


2010 ◽  
Vol 19 (11) ◽  
pp. 1942-1947 ◽  
Author(s):  
Jongbae J. Park ◽  
Joonshik Shin ◽  
Yousuk Youn ◽  
Catherine Champagne ◽  
Eunseok Jin ◽  
...  

1995 ◽  
Vol 44 (4) ◽  
pp. 1293-1295
Author(s):  
Hitoshi Teruya ◽  
Tomoaki Yoshikawa ◽  
Shintoku Isa ◽  
Naoto Hamasaki ◽  
Hajime Tamaki ◽  
...  

2003 ◽  
Vol 22 (1) ◽  
pp. 12-17 ◽  
Author(s):  
E. F. Dubois ◽  
M. F. Wagemans ◽  
B. C. Verdouw ◽  
A. H. Zwinderman ◽  
C. J. van Boxtel ◽  
...  

2014 ◽  
Vol 114 (05) ◽  
pp. 356-367 ◽  
Author(s):  
Karen Snider ◽  
Jane Johnson ◽  
Brian Degenhardt ◽  
Eric Snider ◽  
Douglas Burton

2012 ◽  
Vol 6;15 (6;12) ◽  
pp. 441-449
Author(s):  
Byeongmun Hwang

Background: Therapy with glucocorticoids often results in bone loss and glucocorticoidinduced osteoporosis. However, the relationship between epidural steroid injection (ESI), bone mineral density (BMD), and vertebral fracture remains to be determined. Objective: To establish a relationship between ESI, BMD, and vertebral fracture in postmenopausal women with low back pain. Study Design: This study was a retrospective, nonblinded, cross-sectional clinical study. Setting: University-based pain management center. Methods: We reviewed the medical records of postmenopausal women with low back pain who were treated with ESI. A total of 352 postmenopausal women were divided into 2 groups. Group 1 consisted of patients without fracture and Group 2 consisted of those with fractures. The results of BMD measurements, as well as any fragility fractures, the anatomical site involved, and the treatment administered, were also recorded. BMD was measured in the lumbar spine, femoral neck, and total femur after the treatment. Results: Of the 352 patients, 218 (62%) had no fractures while 134 (38%) sustained a fracture. The age was significantly higher among patients who sustained fractures, and BMD at the lumbar spine, total femur, and femoral neck regions was significantly lower among patients who sustained fractures. In each region, the prevalence of osteoporosis was significantly higher in patients with fracture than in patients without fracture (all P < 0.05). Age, height, and weight were associated with low BMD. However, our study showed no consistent correlation between BMD and the mean number of ESIs, mean total dose of glucocorticoids, or mean duration of ESIs. Limitations: First, this study is limited by the fact that it was retrospective. Second, the number of cases receiving very frequent, high-dose glucocorticoid injections was very small. Conclusions: Older age and lower BMD were associated with osteoporotic fracture in postmenopausal women treated for low back pain with ESI. The ESIs were not associated with low BMD or fracture. Key words: Bone mineral density, epidural steroid injection, fracture, glucocorticoids, low back pain, postmenopause.


2013 ◽  
Vol 7 (2) ◽  
pp. 104 ◽  
Author(s):  
Osama Al-Saeed ◽  
Ahmed Mohammed ◽  
Fawaz Azizieh ◽  
Renu Gupta

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