Genetic diversity and structure among Iranian tall fescue populations based on genomic-SSR and EST-SSR marker analysis

2009 ◽  
Vol 282 (1-2) ◽  
pp. 57-70 ◽  
Author(s):  
Majid Sharifi Tehrani ◽  
Mohsen Mardi ◽  
Jamal Sahebi ◽  
Pilar Catalán ◽  
Antonio Díaz-Pérez
Genetica ◽  
2017 ◽  
Vol 145 (2) ◽  
pp. 189-200 ◽  
Author(s):  
Sujinna Dachapak ◽  
Prakit Somta ◽  
Supalak Poonchaivilaisak ◽  
Tarika Yimram ◽  
Peerasak Srinives

2011 ◽  
Vol 12 (5) ◽  
pp. 1145-1157 ◽  
Author(s):  
Ying-Hui Li ◽  
Marinus J. M. Smulders ◽  
Ru-Zhen Chang ◽  
Li-Juan Qiu

2019 ◽  
Vol 57 (5) ◽  
pp. 652-672 ◽  
Author(s):  
Abhishek Bhandawat ◽  
Vikas Sharma ◽  
Pradeep Singh ◽  
Romit Seth ◽  
Akshay Nag ◽  
...  

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Fehintola V. Ajogbasile ◽  
Adeyemi T. Kayode ◽  
Paul E. Oluniyi ◽  
Kazeem O. Akano ◽  
Jessica N. Uwanibe ◽  
...  

Abstract Background Malaria remains a public health burden especially in Nigeria. To develop new malaria control and elimination strategies or refine existing ones, understanding parasite population diversity and transmission patterns is crucial. Methods In this study, characterization of the parasite diversity and structure of Plasmodium falciparum isolates from 633 dried blood spot samples in Nigeria was carried out using 12 microsatellite loci of P. falciparum. These microsatellite loci were amplified via semi-nested polymerase chain reaction (PCR) and fragments were analysed using population genetic tools. Results Estimates of parasite genetic diversity, such as mean number of different alleles (13.52), effective alleles (7.13), allelic richness (11.15) and expected heterozygosity (0.804), were high. Overall linkage disequilibrium was weak (0.006, P < 0.001). Parasite population structure was low (Fst: 0.008–0.105, AMOVA: 0.039). Conclusion The high level of parasite genetic diversity and low population structuring in this study suggests that parasite populations circulating in Nigeria are homogenous. However, higher resolution methods, such as the 24 SNP barcode and whole genome sequencing, may capture more specific parasite genetic signatures circulating in the country. The results obtained can be used as a baseline for parasite genetic diversity and structure, aiding in the formulation of appropriate therapeutic and control strategies in Nigeria.


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