Full-length genome analysis of vesicular stomatitis New Jersey virus strains representing the phylogenetic and geographic diversity of the virus

2012 ◽  
Vol 157 (11) ◽  
pp. 2247-2251 ◽  
Author(s):  
Steven J. Pauszek ◽  
Luis L. Rodriguez
Keyword(s):  
New Jersey ◽  
Genome Analysis ◽  
Full Length ◽  
Geographic Diversity ◽  
Vesicular Stomatitis ◽  
Full Length Genome ◽  
Virus Strains

Marked genomic heterogeneity of rat hepatitis E virus strains in Indonesia demonstrated on a full-length genome analysis

2014 ◽  
Vol 179 ◽  
pp. 102-112 ◽  
Author(s):  
Mulyanto ◽  
Joseph Benedictus Suparyatmo ◽  
I Gusti Ayu Sri Andayani ◽  
Khalid ◽  
Masaharu Takahashi ◽  
...  
Keyword(s):  
Genome Analysis ◽  
Hepatitis E Virus ◽  
Hepatitis E ◽  
Full Length ◽  
Full Length Genome ◽  
Virus Strains

scholarly journals Regional adaptations and parallel mutations in Feline panleukopenia virus strains from China revealed by nearly-full length genome analysis

PLoS ONE ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. e0227705
Author(s):  
Élcio Leal ◽  
Ruiying Liang ◽  
Qi Liu ◽  
Fabiola Villanova ◽  
Lijun Shi ◽  
...  
Keyword(s):  
Genome Analysis ◽  
Full Length ◽  
Feline Panleukopenia Virus ◽  
Full Length Genome ◽  
Virus Strains

Near full-length genome analysis of HCV genotype 5 strains from South Africa

2014 ◽  
Vol 21 ◽  
pp. 118-123 ◽  
Author(s):  
Maemu P. Gededzha ◽  
Selokela G. Selabe ◽  
Jason T. Blackard ◽  
Thanda Kyaw ◽  
M. Jeffrey Mphahlele
Keyword(s):  
South Africa ◽  
Genome Analysis ◽  
Full Length ◽  
Hcv Genotype ◽  
Genotype 5 ◽  
Full Length Genome

Full-Length Genome Analysis of HIV-1 Subtype C Utilizing CXCR4 and Intersubtype Recombinants Isolated in South Africa

2002 ◽  
Vol 18 (12) ◽  
pp. 879-886 ◽  
Author(s):  
Maria A. Papathanasopoulos ◽  
Tonie Cilliers ◽  
Lynn Morris ◽  
John L. Mokili ◽  
William Dowling ◽  
...  
Keyword(s):  
South Africa ◽  
Genome Analysis ◽  
Full Length ◽  
Subtype C ◽  
Full Length Genome ◽  
Hiv 1

Full-Length Genome Analysis of Human Immunodeficiency Virus Type 1 Subtype C in Brazil

2006 ◽  
Vol 22 (2) ◽  
pp. 171-176 ◽  
Author(s):  
Sabri Sanabani ◽  
Walter Kleine Neto ◽  
Dercy José De Sa Filho ◽  
Ricardo Sobhie Diaz ◽  
Patrícia Munerato ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Human Immunodeficiency Virus Type ◽  
Virus Type ◽  
Genome Analysis ◽  
Full Length ◽  
Subtype C ◽  
Immunodeficiency Virus ◽  
Full Length Genome

scholarly journals Host predilection and transmissibility of vesicular stomatitis New Jersey virus strains in domestic cattle (Bos taurus) and swine (Sus scrofa)

2012 ◽  
Vol 8 (1) ◽  
pp. 183 ◽  
Author(s):  
Paul F Smith ◽  
Elizabeth W Howerth ◽  
Deborah Carter ◽  
Elmer W Gray ◽  
Raymond Noblet ◽  
...  
Keyword(s):  
New Jersey ◽  
Sus Scrofa ◽  
Bos Taurus ◽  
Vesicular Stomatitis ◽  
Virus Strains

scholarly journals Defective Interfering Genomes and the Full-Length Viral Genome Trigger RIG-I After Infection With Vesicular Stomatitis Virus in a Replication Dependent Manner

2021 ◽  
Vol 12 ◽  
Author(s):  
Andreas Linder ◽  
Viktoria Bothe ◽  
Nicolas Linder ◽  
Paul Schwarzlmueller ◽  
Frank Dahlström ◽  
...  
Keyword(s):  
Vesicular Stomatitis Virus ◽  
Full Length ◽  
Oncolytic Viruses ◽  
Interferon Response ◽  
Response Analysis ◽  
Interferon Α ◽  
Dependent Manner ◽  
Viral Genomes ◽  
Vesicular Stomatitis ◽  
Full Length Genome

Replication competent vesicular stomatitis virus (VSV) is the basis of a vaccine against Ebola and VSV strains are developed as oncolytic viruses. Both functions depend on the ability of VSV to induce adequate amounts of interferon-α/β. It is therefore important to understand how VSV triggers interferon responses. VSV activates innate immunity via retinoic acid-inducible gene I (RIG-I), a sensor for viral RNA. Our results show that VSV needs to replicate for a robust interferon response. Analysis of RIG-I-associated RNA identified a copy-back defective-interfering (DI) genome and full-length viral genomes as main trigger of RIG-I. VSV stocks depleted of DI genomes lost most of their interferon-stimulating activity. The remaining full-length genome and leader-N-read-through sequences, however, still triggered RIG-I. Awareness for DI genomes as trigger of innate immune responses will help to standardize DI genome content and to purposefully deplete or use DI genomes as natural adjuvants in VSV-based therapeutics.

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