Design of improved synthetic antifungal peptides with targeted variations in charge, hydrophobicity and chirality based on a correlation study between biological activity and primary structure of plant defensin γ-cores

Amino Acids ◽  
2021 ◽  
Author(s):  
Estefany Braz Toledo ◽  
Douglas Ribeiro Lucas ◽  
Thatiana Lopes Biá Ventura Simão ◽  
Sanderson Dias Calixto ◽  
Elena Lassounskaia ◽  
...  
Keyword(s):  
Biological Activity ◽  
Primary Structure ◽  
Correlation Study ◽  
Plant Defensin ◽  
Antifungal Peptides

Primary structure and biological activity of bradykinin potentiating peptides fromBothrops insularis snake venom

1990 ◽  
Vol 9 (2) ◽  
pp. 221-227 ◽  
Author(s):  
Ad�lia C. O. Cintra ◽  
Carlos A. Vieira ◽  
Jos� R. Giglio
Keyword(s):  
Biological Activity ◽  
Snake Venom ◽  
Primary Structure

scholarly journals A correlation study of biological activity and molecular docking of Asp and Glu linked bis-hydrazones of quinazolinones

RSC Advances ◽  
2018 ◽  
Vol 8 (19) ◽  
pp. 10644-10653 ◽  
Author(s):  
H. K. Kumara ◽  
R. Suhas ◽  
D. M. Suyoga Vardhan ◽  
M. Shobha ◽  
D. Channe Gowda
Keyword(s):  
Biological Activity ◽  
Molecular Docking ◽  
Glutamic Acid ◽  
Aspartic Acid ◽  
Correlation Study

The present investigation involves the synthesis and spectroscopic and biological activity studies of the bis-hydrazones of quinazolinones derived from aspartic acid and glutamic acid.

Isolement et caractérisation chimique des lipopolysaccharides de type R dans une souche hypovirulente de Yersinia pestis

1998 ◽  
Vol 44 (5) ◽  
pp. 477-481 ◽  
Author(s):  
S Minka ◽  
M Bruneteau
Keyword(s):  
Biological Activity ◽  
Hydrochloric Acid ◽  
Yersinia Pestis ◽  
Primary Structure ◽  
Gel Electrophoresis ◽  
Lipid A ◽  
Solvent Mixture ◽  
Chloroform Methanol

The lipopolysaccharides LPS I and LPS II, isolated from the hypovirulent EV40 strain of Yersinia pestis, are composed only of type R lipopolysaccharides. This type consists of two forms, a and b, depending on their solubility pattern in a solvent mixture containing varying proportions of chloroform, methanol, hexane, and hydrochloric acid. LPS I consists of one subtype, RIb, while LPS II consists of two subtypes, RIIa and RIIb. Analysis by gel electrophoresis shows that the mass of these lipopolysaccharide forms are in the vicinity of 2000-3000 Da. The RIb and RIIb subtypes, which are found in the majority of lipopolysaccharide I and II fractions, are composed of ketoses and amines that are similar to those occurring in LPS I and LPS II. In contrast, the two subtypes RIIa and RIIb are different both in terms of the composition of lipid A and the extent of its substitution. Certain fractions of RIIa contain only lipid A and 3-deoxy-D-manno-octulosonic acid (KDO), while other fractions of RIIb possess a lipid A, which is not substituted by arabinose. The whole set of these R-type lipopolysaccharide forms are excellent models for the study of the role of the primary structure of the polysaccharide region, and for the effect of lipid A substitution on the biological activity of bacterial lipopolysaccharides.Key words: Yersinia pestis, hypovirulence, lipopolysaccharides, R type.[Journal translation]

scholarly journals Xylocandin: A new complex of antifungal peptides. I. Taxonomy, isolation and biological activity.

1987 ◽  
Vol 40 (11) ◽  
pp. 1515-1519 ◽  
Author(s):  
E. MEYERS ◽  
G. S. BISACCHI ◽  
L. DEAN ◽  
W. C. Liu ◽  
B. MINASSIAN ◽  
...  
Keyword(s):  
Biological Activity ◽  
Antifungal Peptides

Primary structure, tissue distribution, and biological activity of chicken motilin receptor

2008 ◽  
Vol 156 (3) ◽  
pp. 509-514 ◽  
Author(s):  
Ichiro Yamamoto ◽  
Hiroyuki Kaiya ◽  
Chihiro Tsutsui ◽  
Takafumi Sakai ◽  
Akira Tsukada ◽  
...  
Keyword(s):  
Biological Activity ◽  
Tissue Distribution ◽  
Primary Structure ◽  
Motilin Receptor

Relationship between chemical structure and biological activity of hen egg-white lysozyme and lysozymes of different species

1967 ◽  
Vol 167 (1009) ◽  
pp. 350-364 ◽  
Keyword(s):  
Biological Activity ◽  
Primary Structure ◽  
Chemical Structure ◽  
Egg White ◽  
Hen Egg White Lysozyme ◽  
Physical Methods ◽  
Egg White Lysozyme ◽  
Disulphide Bonds ◽  
Hen Egg White ◽  
Hen Egg

Fleming discovered an enzyme which he called lysozyme; it had ‘the power of rapidly dissolving certain bacteria, which is possessed by many animal and vegetable tissues and secretions and to a very marked degree by egg-white' (Fleming 1922). Hen egg-white lysozyme was crystallized by Abraham & Robinson in 1937; its homogeneity was verified by different chromatographic and physical methods, which have recently been reviewed (Jollès, P. 1960, 1964). Since 1958, Jollès and others have been engaged in elucidating the primary structure; they published a preliminary formula in 1961 (Jollès, J. & Jollès, P. 1961), followed in 1963 by a detailed study (Jollès, J., Jauregui-Adell, Bernier & Jollès, P. 1963); their structure differed slightly from that of Canfield (1963). The positions of the four disulphide bonds were also established (see table 1), and the complete formula is indicated in figure 1.

Studies on the primary structure and biological activity of a human neurophysin

FEBS Letters ◽  
1973 ◽  
Vol 30 (2) ◽  
pp. 151-156 ◽  
Author(s):  
Irene Foss ◽  
Knut Sletten ◽  
Olav Trygstad
Keyword(s):  
Biological Activity ◽  
Primary Structure
Sign in / Sign up

Export Citation Format

Share Document