scholarly journals BglII gene polymorphism of the α2β1 integrin gene is a risk factor for diabetic retinopathy in Caucasians with type 2 diabetes

2003 ◽  
Vol 48 (9) ◽  
pp. 457-460 ◽  
Author(s):  
Mojca Globočnik Petrovič ◽  
Marko Hawlina ◽  
Borut Peterlin ◽  
Daniel Petrovič
2021 ◽  
Vol 8 (12) ◽  
pp. 1-6
Author(s):  
Astri Meliana ◽  
Desak Made Wihandani ◽  
Ni Nyoman Ayu Dewi

Introduction: Diabetic retinopathy (DR) is a microvascular disorder of the retina caused by hyperglycemia in the blood vessels and is the most common complication in the eye due to diabetes mellitus (DM). The aim of this study was to determine the VEGF -460C/T gene polymorphism as a risk factor for diabetic retinopathy in T2DM patients in Bali. Materials and Methods: The design of this study was case-control with 27 cases of type 2 DM with DR and 29 cases without RD as controls. The VEGF-460C/T polymorphism in DNA was detected using PCR and DNA sequencing at rs833061 to see the distribution of the C/T allele variation. Data were analyzed using chi-square test. Results: Based on bivariate analysis comparing homozygous TT genotype variants, heterozygous CT and wild-type CC in this study, no significant relationship was found with the incidence of DR (p=0.742). Conclusion: Polymorphism of the VEGF-460C/T gene (rs833061) can be concluded as an irrelevant factor with the risk of developing DR in type 2 diabetes mellitus patients in Bali. Keywords: VEGF -460C/T, Diabetes Mellitus, Polymorphism, Risk Factors.


2004 ◽  
Vol 137 (6) ◽  
pp. 1171-1172
Author(s):  
B. Peterlin ◽  
M. Globočnik Petrovič ◽  
J. Makuc ◽  
M. Hawlina ◽  
D. Petrovič

2005 ◽  
Vol 19 (2) ◽  
pp. 70-73 ◽  
Author(s):  
Mojca Globočnik Petrovič ◽  
Borut Peterlin ◽  
Marko Hawlina ◽  
Daniel Petrovič

2003 ◽  
Vol 48 (12) ◽  
pp. 646-649 ◽  
Author(s):  
Borut Peterlin ◽  
Mojca Globočnik Petrovič ◽  
Jana Makuc ◽  
Marko Hawlina ◽  
Daniel Petrovič

2015 ◽  
Vol 41 (5) ◽  
pp. 429-431 ◽  
Author(s):  
S. Hamamoto ◽  
H. Kaneto ◽  
S. Kamei ◽  
M. Shimoda ◽  
K. Tawaramoto ◽  
...  

Gene Reports ◽  
2020 ◽  
Vol 21 ◽  
pp. 100865
Author(s):  
Hadeel Ahmed Shawki ◽  
Rasha Elzehery ◽  
Ekbal M. Abo-hashem ◽  
Maha Shahin ◽  
Magdy M. Youssef

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