Relative Potency of Telithromycin, Azithromycin and Erythromycin Against Recent Clinical Isolates of Gram-Positive Cocci

2001 ◽  
Vol 20 (7) ◽  
pp. 0494-0497 ◽  
Author(s):  
A. L. Barry ◽  
P. C. Fuchs ◽  
S. D. Brown
1976 ◽  
Vol 4 (4) ◽  
pp. 330-333
Author(s):  
P A Wideman ◽  
V L Vargo ◽  
D Citronbaum ◽  
S M Finegold

The previously reported sodium polyanethol sulfonate disk test for the identification of Peptostreptococcus anaerobius (Graves et al., 1974) was evaluated, with modifications. Three bands of brucella agar, three inoculum sizes, and two inoculum sources were compared. Nine stock cultures of P. anaerobius (eight normal flora isolates and ATCC 27337) and 16 fresh clinical isolates were used. All cultures of P. anaerobius showed inhibition zones of 12 to 30 mm in diameter, regardless of test conditions. Out of 103 clinical isolates of other species of anaerobic gram-positive cocci tested, only two had an inhibition zone size in this range (one P. micros of 11 studied had a zone of 12 mm and one P. prevotii of 14 studied had a zone of 16). The test had an overall accuracy of 98% in the identification of P. anaerobius from clinical specimens. Since P. anaerobius accounts for one-fifth to one-third of all anaerobic gram-positive cocci encountered in clinical specimens, this simple and rapid technique can be very useful for presumptive identification.


2003 ◽  
Vol 47 (1) ◽  
pp. 400-404 ◽  
Author(s):  
D. Milatovic ◽  
F.-J. Schmitz ◽  
J. Verhoef ◽  
A. C. Fluit

ABSTRACT The in vitro activities of tigecycline against 1,924 clinical isolates were examined. The new glycylcycline exhibited excellent activity against all gram-positive cocci (MICs at which 90% of the isolates tested were inhibited [MIC90s], ≤1 μg/ml). In addition, it was also very potent against most members of the Enterobacteriaceae, with most MIC90s being ≤2 μg/ml. Among the nonfermenters, Acinetobacter spp. and Stenotrophomonas maltophilia are included in the in vitro spectrum of tigecycline activity.


2004 ◽  
Vol 36 (4) ◽  
pp. 254-258 ◽  
Author(s):  
Gunnar S. Simonsen ◽  
Kåre Bergh ◽  
Lars Bevanger ◽  
Asbjørn Digranes ◽  
Peter Gaustad ◽  
...  

2008 ◽  
Vol 32 ◽  
pp. S184-S187 ◽  
Author(s):  
Shih-Ming Tsao ◽  
Hsiu-Chen Lin ◽  
Chun-Ming Lee ◽  
Gwo-Jong Hsu ◽  
Chih-Ming Chen ◽  
...  

2020 ◽  
Vol 26 (2) ◽  
pp. 126-135
Author(s):  
Reza Beigverdi ◽  
Azin Sattari-Maraji ◽  
Fereshteh Jabalameli ◽  
Mohammad Emaneini

Author(s):  
James A. Karlowsky ◽  
Melanie R. Baxter ◽  
Alyssa R. Golden ◽  
Heather J. Adam ◽  
Andrew Walkty ◽  
...  

Clinical isolates of Enterobacterales other than Escherichia coli (EOTEC), non-fermenting Gram-negative bacilli, and Gram-positive cocci were tested for susceptibility to fosfomycin using Etest ® and reference agar dilution. Applying EUCAST (v. 11.0, 2021) intravenous fosfomycin breakpoints, Etest ® MICs for EOTEC showed essential agreement (EA), categorical agreement (CA), major error (ME), and very major error (VME) rates of 70.4%, 88.4%, 4.1%, and 32.1%, respectively. No species of EOTEC tested with acceptable rates for all of EA (≥90%), CA (≥90%), ME (≤3%), and VME (≤3%). Etest ® MICs for Enterococcus faecalis , interpreted using CLSI oral/urine criteria (M100, 2021), showed EA, CA, minor error, ME, and VME rates of 98.5%, 81.2%, 18.8%, 0%, and 0%. Against Staphylococcus aureus , EA, CA, and ME rates were 84.1%, 98.7%, and 1.3% (EUCAST intravenous criteria). S. aureus isolates with fosfomycin MICs >32 μg/ml (resistant) were not identified by agar dilution. We conclude performing fosfomycin Etest ® on isolates of S. aureus will reliably identify fosfomycin-susceptible isolates with low, acceptable rates of MEs and VMEs. Testing of urinary isolates of E. faecalis by Etest ® is associated with an unacceptably high rate of minor errors (18.8%) but low, acceptable rates of MEs and VMEs when results are interpreted using CLSI criteria. Isolates of EOTEC tested by Etest ® with resulting MICs interpreted by EUCAST criteria were associated with an unacceptably high VME rate (32.1%). In vitro testing of clinical isolates beyond E. coli , E. faecalis , and S. aureus to determine susceptibility to fosfomycin is problematic with current methods and breakpoints.


2019 ◽  
Vol 31 (4) ◽  
pp. 188-194 ◽  
Author(s):  
Michael A. Pfaller ◽  
Helio S. Sader ◽  
Dee Shortridge ◽  
Mariana Castanheira ◽  
Robert K. Flamm ◽  
...  

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