High variance of intraoperative blood pressure predicts early cerebral infarction after revascularization surgery in patients with Moyamoya disease

2019 ◽  
Vol 43 (2) ◽  
pp. 759-769
Author(s):  
Jiaxi Li ◽  
Yahui Zhao ◽  
Meng Zhao ◽  
Penghui Cao ◽  
Xingju Liu ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cerebral Infarction ◽  
Moyamoya Disease ◽  
Revascularization Surgery

scholarly journals Benefits and risks of antiplatelet medication in hemodynamically stable adult moyamoya disease

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Chang Hwan Pang ◽  
Won-Sang Cho ◽  
Hyun-Seung Kang ◽  
Jeong Eun Kim
Keyword(s):  
Cerebral Infarction ◽  
Moyamoya Disease ◽  
Standard Treatment ◽  
Antiplatelet Agents ◽  
Medical Data ◽  
Antiplatelet Medication ◽  
Drug Potency ◽  
Adult Moyamoya Disease ◽  
Revascularization Surgery

AbstractRevascularization surgery is considered a standard treatment for preventing additional stroke in symptomatic moyamoya disease (MMD). In hemodynamically stable, and asymptomatic or mildly symptomatic patients, however, the treatment strategy is controversial because of the obscure natural course of them. The authors analyzed the benefits and risks of antiplatelet medication in those patients. Medical data were retrospectively reviewed in 439 hemispheres of 243 patients with stable hemodynamic status. Overall, 121 patients (49.8%) with 222 studied hemispheres (50.6%) took antiplatelet medication. Symptomatic cerebral infarction and hemorrhage occurred in 10 (2.3%) and 30 (6.8%) hemispheres, over a mean follow-up of 62.0 ± 43.4 months (range 6–218 months). The use of antiplatelet agents was statistically insignificant in terms of symptomatic infarction, hemorrhage and improvement of ischemic symptoms. In subgroup analyses within the antiplatelet group according to drug potency and duration of medication, a longer duration of antiplatelet medication significantly improved ischemic symptoms (adjusted OR 1.02; 95% CI 1.01–1.03; p = 0.006). Antiplatelet medication failed to prevent symptomatic cerebral infarction or improve ischemic symptoms. However, antiplatelet therapy did not increase the risk of cerebral hemorrhage.

Intralateral and Perilateral Ventricular Arteries on Original Axial Magnetic Resonance Angiography in Adult Moyamoya Disease

2021 ◽  
Vol 84 (2) ◽  
pp. 119-123
Author(s):  
Mami Ishikawa ◽  
Satoshi Terao ◽  
Hiroshi Kagami ◽  
Makoto Inaba ◽  
Heiji Naritaka
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Angiography ◽  
Cerebral Infarction ◽  
Moyamoya Disease ◽  
Disease Onset ◽  
Time Of Flight ◽  
Unruptured Aneurysms ◽  
Tof Mra ◽  
Adult Moyamoya Disease

<b><i>Background:</i></b> Patients with moyamoya disease often develop cerebral infarction and hemorrhage, but the ischemic and hemorrhagic subtypes are difficult to diagnose prior to disease onset. We aimed to differentiate the ischemic and hemorrhagic subtypes of moyamoya disease by analyzing the intralateral and perilateral ventricular arteries on the original axial magnetic resonance angiography (MRA) images. <b><i>Methods:</i></b> We retrospectively analyzed the intralateral and perilateral ventricular arteries on the original axial time-of-flight (TOF)-MRA images of 18 patients with hemorrhagic moyamoya disease, 25 patients with ischemic moyamoya disease, and 22 control patients with unruptured aneurysms. <b><i>Results:</i></b> There were significantly more intralateral and perilateral ventricular arteries on the original axial MRA images in the patients with hemorrhagic moyamoya disease (6.3 ± 2.7) than in those with ischemic moyamoya disease (0.8 ± 0.9) and those with unruptured aneurysms (0.4 ± 0.8). <b><i>Conclusion:</i></b> The intralateral and perilateral ventricular arteries on the original axial TOF-MRA images might suggest the hemorrhagic type of moyamoya disease prior to onset.

scholarly journals Abnormal blood pressure circadian rhythms are relevant to cerebral infarction and Leukoaraiosis in hypertensive patients

BMC Neurology ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Kang Yang ◽  
Xiaodong Zhu ◽  
Yulan Feng ◽  
Fanxia Shen ◽  
Jie Chen ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Circadian Rhythms ◽  
Cerebral Infarction ◽  
Hypertensive Patients
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