scholarly journals Indications for fertility preservation not included in the 2017 Japan Society of Clinical Oncology Guideline for Fertility Preservation in Pediatric, Adolescent, and Young Adult Patients treated with gonadal toxicity, including benign diseases

Author(s):  
Masanori Ono ◽  
Kimikazu Matsumoto ◽  
Narikazu Boku ◽  
Nobuharu Fujii ◽  
Yumi Tsuchida ◽  
...  
Cancer ◽  
2015 ◽  
Vol 121 (19) ◽  
pp. 3499-3506 ◽  
Author(s):  
Margarett Shnorhavorian ◽  
Linda C. Harlan ◽  
Ashley Wilder Smith ◽  
Theresa H.M. Keegan ◽  
Charles F. Lynch ◽  
...  

Author(s):  
Miyuki Harada ◽  
Fuminori Kimura ◽  
Yasushi Takai ◽  
Takeshi Nakajima ◽  
Kimio Ushijima ◽  
...  

AbstractIn 2017, the Japan Society of Clinical Oncology (JSCO) published the JSCO Clinical Practice Guidelines 2017 for Fertility Preservation in Childhood, Adolescent, and Young Adult Cancer Patients. These were the first Japanese guidelines to address issues of oncofertility. In this field of medicine, sustained close cooperation between oncologists and reproductive specialists is essential from the diagnosis of cancer until many years after completion of cancer treatment. These JSCO guidelines were intended to guide multidisciplinary medical staff in considering the availability of fertility preservation options and to help them decide whether to provide fertility preservation to childhood, adolescent, and young adult cancer patients before treatment starts, with the ultimate goal of improving patient survivorship. The guidelines are presented as Parts 1 and 2. This article (Part 1) summarizes the goals of the guidelines and the methods used to develop them and provides an overview of fertility preservation across all oncology areas. It includes general remarks on the basic concepts surrounding fertility preservation and explanations of the impacts of cancer treatment on gonadal function by sex and treatment modality and of the options for protecting/preserving gonadal function and makes recommendations based on 4 clinical questions. Part 2 of these guidelines provides specific recommendations on fertility preservation in 8 types of cancer (gynecologic, breast, urologic, pediatric, hematologic, bone and soft tissue, brain, and digestive).


2019 ◽  
Vol 112 (3) ◽  
pp. e67
Author(s):  
Megan R. Sax ◽  
Tara Schafer-Kalkhoff ◽  
Brycen Ferrara ◽  
Olivia Jaworek Frias ◽  
Lesley Breech ◽  
...  

Author(s):  
Christabel K. Cheung ◽  
Patricia W. Nishimoto ◽  
Thuli Katerere-Virima ◽  
Laura E. Helbling ◽  
Bria N. Thomas ◽  
...  

2021 ◽  
Author(s):  
Kjersti J. Ø. Fløtten ◽  
Ana Isabel Fernandes Guerreiro ◽  
Ilaria Simonelli ◽  
Anne Lee Solevåg ◽  
Isabelle Aujoulat

2021 ◽  
Vol 9 (7_suppl3) ◽  
pp. 2325967121S0005
Author(s):  
Mahad M. Hassan ◽  
Omar F. Rahman ◽  
Zaamin B. Hussain ◽  
Stephane L. Burgess ◽  
Yi-Meng Yen ◽  
...  

Background: Previous studies have examined factors related to the increased use of opioids after hip arthroscopy in adults. However, few have focused on the adolescent population. Purpose: The purpose of this study was to compare the opioids prescribed to opioids consumed after hip arthroscopic procedures in adolescent and young adult patients, and to determine patient or surgical factors associated with increased postoperative opioid use. Methods: Adolescent and young adult patients who underwent hip arthroscopy and associated arthroscopic interventions between January 2017 and January 2020 were included. Patients with a diagnosed pain syndrome or history of chronic pain, as determined by the patient taking opioid medications prior to surgery, were excluded. Daily postoperative opioid intake was recorded via pain-control logbooks. The outcome of the study was defined as the average total number of opioid tablets consumed postoperatively. Results: Fifty-eight patients returned completed logbooks, 72% of whom were female patients. The average age was 21.30 years (range, 14.9 – 34.2). Most patients (73%) were prescribed 30 oxycodone tablets. The median amount of tablets consumed was 7 (range, 0-41) over a median duration of 7 days (range, 1-22). The median ratio of tablets consumed to prescribed was 20% and the 95th percentile of opioids consumed was 28 tablets. Bivariate analysis showed that patient age at surgery was positively correlated to the total amount of tablets consumed (r=0.28, p=0.04) and to the ratio of tablets consumed to prescribed (r=0.30, p=0.03). Duration of surgery was negatively correlated to the number of days tablets were consumed (r=-0.31, p=0.03). Multivariate analysis showed that patients who were prescribed more than 30 tablets took on average 7.8 more tablets overall compared to those prescribed 30 or fewer tablets (p=0.003), and that for each additional year of age, the ratio of tablets consumed to prescribed increased by 1% (p=0.02). Conclusion: After undergoing hip arthroscopy and associated arthroscopic procedures, adolescents and young adult patients are commonly overprescribed opioids, consuming on average only one-fifth of the tablets prescribed. This finding mirrors trends in the pediatric knee arthroscopy literature and provides an opportunity to reassess current opioid prescribing behaviors in the adolescent and young adult populations. [Table: see text][Table: see text][Table: see text][Table: see text][Table: see text]


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