In vitro and in vivo study of human amniotic fluid-derived stem cell differentiation into myogenic lineage

2009 ◽  
Vol 10 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Jean Gekas ◽  
Guillaume Walther ◽  
Daniel Skuk ◽  
Emmanuel Bujold ◽  
Isabelle Harvey ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cell Differentiation ◽  
Amniotic Fluid ◽  
Stem Cell Differentiation ◽  
In Vivo Study ◽  
Human Amniotic Fluid ◽  
Myogenic Lineage

scholarly journals Human adipose stem cell differentiation is highly affected by cancer cells both in vitro and in vivo: implication for autologous fat grafting

2017 ◽  
Vol 8 (1) ◽  
pp. e2568-e2568 ◽  
Author(s):  
Francesca Paino ◽  
Marcella La Noce ◽  
Diego Di Nucci ◽  
Giovanni Francesco Nicoletti ◽  
Rosa Salzillo ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cell Differentiation ◽  
Stem Cell Differentiation ◽  
Fat Grafting ◽  
Adipose Stem Cell ◽  
Autologous Fat Grafting ◽  
Autologous Fat ◽  
Human Adipose Stem Cell

scholarly journals Functions of Circular RNAs in Regulating Adipogenesis of Mesenchymal Stem Cells

2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Fanglin Wang ◽  
Xiang Li ◽  
Zhiyuan Li ◽  
Shoushuai Wang ◽  
Jun Fan
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Stem Cell ◽  
Cell Differentiation ◽  
Stem Cell Differentiation ◽  
Circular Rna ◽  
Circular Rnas ◽  
Differentiation Process

The mesenchymal stem cells (MSCs) are known as highly plastic stem cells and can differentiate into specialized tissues such as adipose tissue, osseous tissue, muscle tissue, and nervous tissue. The differentiation of mesenchymal stem cells is very important in regenerative medicine. Their differentiation process is regulated by signaling pathways of epigenetic, transcriptional, and posttranscriptional levels. Circular RNA (circRNA), a class of noncoding RNAs generated from protein-coding genes, plays a pivotal regulatory role in many biological processes. Accumulated studies have demonstrated that several circRNAs participate in the cell differentiation process of mesenchymal stem cells in vitro and in vivo. In the current review, characteristics and functions of circRNAs in stem cell differentiation will be discussed. The mechanism and key role of circRNAs in regulating mesenchymal stem cell differentiation, especially adipogenesis, will be reviewed and discussed. Understanding the roles of these circRNAs will present us with a more comprehensive signal path network of modulating stem cell differentiation and help us discover potential biomarkers and therapeutic targets in clinic.

scholarly journals Tuberin and PRAS40 are anti-apoptotic gatekeepers during early human amniotic fluid stem-cell differentiation

2011 ◽  
Vol 21 (5) ◽  
pp. 1049-1061 ◽  
Author(s):  
Christiane Fuchs ◽  
Margit Rosner ◽  
Helmut Dolznig ◽  
Mario Mikula ◽  
Nina Kramer ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cell Differentiation ◽  
Amniotic Fluid ◽  
Stem Cell Differentiation ◽  
Human Amniotic Fluid ◽  
Amniotic Fluid Stem Cell ◽  
Early Human

BMP15 Gene Is Activated During Human Amniotic Fluid Stem Cell Differentiation into Oocyte-Like Cells

2012 ◽  
Vol 31 (7) ◽  
pp. 1198-1204 ◽  
Author(s):  
Xiang Cheng ◽  
Shuai Chen ◽  
Xiaoli Yu ◽  
Pengsheng Zheng ◽  
Huayan Wang
Keyword(s):  
Stem Cell ◽  
Cell Differentiation ◽  
Amniotic Fluid ◽  
Stem Cell Differentiation ◽  
Human Amniotic Fluid ◽  
Amniotic Fluid Stem Cell

scholarly journals Decellularized Extracellular Matrix as anIn VitroModel to Study the Comprehensive Roles of the ECM in Stem Cell Differentiation

2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Takashi Hoshiba ◽  
Guoping Chen ◽  
Chiho Endo ◽  
Hiroka Maruyama ◽  
Miyuki Wakui ◽  
...  
Keyword(s):  
Stem Cells ◽  
Extracellular Matrix ◽  
Stem Cell ◽  
Cell Differentiation ◽  
Regenerative Medicine ◽  
Intracellular Signaling ◽  
Complex Structure ◽  
Stem Cell Differentiation

Stem cells are a promising cell source for regenerative medicine. Stem cell differentiation must be regulated for applications in regenerative medicine. Stem cells are surrounded by extracellular matrix (ECM)in vivo. The ECM is composed of many types of proteins and glycosaminoglycans that assemble into a complex structure. The assembly of ECM molecules influences stem cell differentiation through orchestrated intracellular signaling activated by many ECM molecules. Therefore, it is important to understand the comprehensive role of the ECM in stem cell differentiation as well as the functions of the individual ECM molecules. Decellularized ECM is a usefulin vitromodel for studying the comprehensive roles of ECM because it retains a native-like structure and composition. Decellularized ECM can be obtained fromin vivotissue ECM or ECM fabricated by cells culturedin vitro. It is important to select the correct decellularized ECM because each type has different properties. In this review, tissue-derived and cell-derived decellularized ECMs are compared asin vitroECM models to examine the comprehensive roles of the ECM in stem cell differentiation. We also summarize recent studies using decellularized ECM to determine the comprehensive roles of the ECM in stem cell differentiation.

scholarly journals Nesprin-1 has key roles in the process of mesenchymal stem cell differentiation into cardiomyocyte-like cells in vivo and in vitro

2014 ◽  
Vol 11 (1) ◽  
pp. 133-142 ◽  
Author(s):  
WENGANG YANG ◽  
HUI ZHENG ◽  
YONGYI WANG ◽  
FENG LIAN ◽  
ZHENGLEI HU ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cell Differentiation ◽  
Mesenchymal Stem Cell ◽  
Stem Cell Differentiation ◽  
Mesenchymal Stem Cell Differentiation

scholarly journals Human amniotic fluid stem cell differentiation along smooth muscle lineage

2013 ◽  
Vol 27 (12) ◽  
pp. 4853-4865 ◽  
Author(s):  
Marco Ghionzoli ◽  
Andrea Repele ◽  
Laura Sartiani ◽  
Giulia Costanzi ◽  
Astrid Parenti ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Stem Cell ◽  
Cell Differentiation ◽  
Amniotic Fluid ◽  
Stem Cell Differentiation ◽  
Human Amniotic Fluid ◽  
Amniotic Fluid Stem Cell

scholarly journals The dynamic emergence of GATA1 complexes identified in in vitro embryonic stem cell differentiation and in vivo mouse fetal liver

Haematologica ◽  
2019 ◽  
Vol 105 (7) ◽  
pp. 1802-1812
Author(s):  
Xiao Yu ◽  
Andrea Martella ◽  
Petros Kolovos ◽  
Mary Stevens ◽  
Ralph Stadhouders ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cell Differentiation ◽  
Embryonic Stem Cell ◽  
Fetal Liver ◽  
Embryonic Stem ◽  
Stem Cell Differentiation ◽  
Embryonic Stem Cell Differentiation
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