MR imaging of degenerative disc disease in the lumbar spine with ultrashort TE pulse sequences

2004 ◽  
Vol 16 (4) ◽  
pp. 160-166 ◽  
Author(s):  
Peter D. Gatehouse ◽  
Taigang He ◽  
Sean P. F. Hughes ◽  
Graeme M. Bydder
Keyword(s):  
Lumbar Spine ◽  
Mr Imaging ◽  
Degenerative Disc Disease ◽  
Pulse Sequences ◽  
Disc Disease ◽  
Degenerative Disc

scholarly journals Effect of Core Stabilizing Training on Young Individuals Presenting Different Stages of Degenerative Disc Disease—Preliminary Report

2021 ◽  
Vol 18 (7) ◽  
pp. 3499
Author(s):  
Tomasz Kuligowski ◽  
Błażej Cieślik ◽  
Natalia Kuciel ◽  
Agnieszka Dębiec-Bąk ◽  
Anna Skrzek
Keyword(s):  
Lumbar Spine ◽  
Outcome Measures ◽  
Degenerative Disc Disease ◽  
Preliminary Report ◽  
Primary Outcome ◽  
Core Stability ◽  
Post Intervention ◽  
Disc Disease ◽  
Degenerative Disc

The aim of this study was to assess the efficacy of stabilizing training for the deep core muscles of the lumbar spine in subjects with degenerative disc disease. This study was conducted on 38 participants. The participants were divided into two groups: the extrusion group (EXT, n = 17) and the protrusion group (PRO, n = 21). All the subjects underwent a four-week-long core stability exercise-based treatment (five sessions/week). Clinical outcome measures were assessed pre-intervention (pre), post-intervention (post) and four weeks after the intervention (follow-up). The primary outcome measures were the spinal range of motion (ROM; Spinal Mouse® device) and the Oswestry Disability Index (ODI). In the PRO group, the ROM decreased from 88.52° pre-intervention to 83.33° post-intervention and to 82.82° at follow-up (p = 0.01), while the ODI decreased from 16.14 points pre-intervention to 6.57 points post-intervention, with 9.42 points at follow-up (p < 0.01). In the EXT group, the ROM decreased from 81.00° pre-intervention to 77.05° post-intervention, then increased to 77.94° at follow-up (p = 0.03), while the ODI decreased from 22.58 points pre-intervention to 15.41 points post-intervention and to 14.70 points at follow-up (p < 0.001). Although the stabilizing exercise sessions improved the clinical outcomes in each group, we cannot make conclusions as to whether the type of intervertebral disc damage significantly affects the results of stabilizing exercise-based treatment.

Long-term outcome of fusion for degenerative disc disease in the lumbar spine

2019 ◽  
Vol 101-B (12) ◽  
pp. 1526-1533 ◽  
Author(s):  
Peter Endler ◽  
Per Ekman ◽  
Ivan Berglund ◽  
Hans Möller ◽  
Paul Gerdhem
Keyword(s):  
Back Pain ◽  
Lumbar Spine ◽  
Degenerative Disc Disease ◽  
Interbody Fusion ◽  
Patient Reported Outcome ◽  
Posterolateral Fusion ◽  
Disc Disease ◽  
Degenerative Disc ◽  
Additional Surgery ◽  
Patient Reported

AimsChronic low back pain due to degenerative disc disease is sometimes treated with fusion. We compared the outcome of three different fusion techniques in the Swedish Spine Register: noninstrumented posterolateral fusion (PLF), instrumented posterolateral fusion (IPLF), and interbody fusion (IBF).Patients and MethodsA total of 2874 patients who were operated on at one or two lumbar levels were followed for a mean of 9.2 years (3.6 to 19.1) for any additional lumbar spine surgery. Patient-reported outcome data were available preoperatively (n = 2874) and at one year (n = 2274), two years (n = 1958), and a mean of 6.9 years (n = 1518) postoperatively and consisted of global assessment and visual analogue scales of leg and back pain, Oswestry Disability Index, EuroQol five-dimensional index, 36-Item Short-Form Health Survey, and satisfaction with treatment. Statistical analyses were performed with competing-risks proportional hazards regression or analysis of covariance, adjusted for baseline variables.ResultsThe number of patients with additional surgery were 32/183 (17%) in the PLF group, 229/1256 (18%) in the IPLF group, and 439/1435 (31%) in the IBF group. With the PLF group as a reference, the hazard ratio for additional lumbar surgery was 1.16 (95% confidence interval (CI) 0.78 to 1.72) for the IPLF group and 2.13 (95% CI 1.45 to 3.12) for the IBF group. All patient-reported outcomes improved after surgery (p < 0.001) but were without statistically significant differences between the groups at the one-, two- and 6.9-year follow-ups (all p ≥ 0.12).ConclusionThe addition of interbody fusion to posterolateral fusion was associated with a higher risk for additional surgery and showed no advantages in patient-reported outcome Cite this article: Bone Joint J 2019;101-B:1526–1533

Stand-alone Anterior Lumbar Interbody Fusion for Degenerative Disc Disease of the Lumbar Spine

Spine ◽  
2014 ◽  
Vol 39 (15) ◽  
pp. E894-E901 ◽  
Author(s):  
John Lammli ◽  
M. Camden Whitaker ◽  
Alan Moskowitz ◽  
Jennifer Duong ◽  
Frank Dong ◽  
...  
Keyword(s):  
Lumbar Spine ◽  
Degenerative Disc Disease ◽  
Interbody Fusion ◽  
Anterior Lumbar Interbody Fusion ◽  
Lumbar Interbody Fusion ◽  
Disc Disease ◽  
Degenerative Disc

scholarly journals Evidence that bone mineral density plays a role in degenerative disc disease: the UK Twin Spine Study

2010 ◽  
Vol 69 (12) ◽  
pp. 2102-2106 ◽  
Author(s):  
Gregory Livshits ◽  
Sergey Ermakov ◽  
Maria Popham ◽  
Alex J MacGregor ◽  
Philip N Sambrook ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Lumbar Spine ◽  
Bone Mineral ◽  
Degenerative Disc Disease ◽  
Large Population ◽  
Population Sample ◽  
Population Based ◽  
Mineral Density ◽  
Disc Disease ◽  
Degenerative Disc

ObjectiveOsteoarthritis (OA) and osteoporosis are often considered to lie at opposite ends of a spectrum of bone phenotypes. Lumbar degenerative disc disease (LDD) may be associated with low back pain (LBP) and is similar in many ways to OA. LDD is reported in small studies to be associated with increased spine bone mineral density (BMD). The present work aimed to confirm this association in a large population sample using MRI and explore the relationship further, in particular to determine whether it is mediated genetically.MethodsA population based sample (N=908, age range 32–74 years) of UK female twins having MRI of the lumbar spine was used in this study. LDD traits and summary measures and their relationship with BMD at the lumbar spine and hip were examined using multivariate multiple regression and maximum likelihood based variance decomposition.ResultsThere was a significant positive correlation between LDD and BMD at the lumbar spine and hip, which remained significant after adjustment for confounders. Both traits were highly heritable and the associations between them were mediated genetically.ConclusionsA clear, significant and independent association of BMD at hip and lumbar spine with LDD was found which is, in part, genetically mediated. The association with the non-axial site, the hip, is of particular interest and suggests a systemic bone effect. This should encourage the search for pleiotropic genes to help in the understanding of the bone–cartilage relationship. Moreover, genetic variants identified could provide novel therapeutic targets in the management of LBP.

P24. Posterior Dynamic Instrumentation (Isobar TTL) for Degenerative Disc Disease of Lumbar Spine

2009 ◽  
Vol 9 (10) ◽  
pp. 128S
Author(s):  
Antonio Castellvi ◽  
Deborah Clabeaux ◽  
William Hudson
Keyword(s):  
Lumbar Spine ◽  
Degenerative Disc Disease ◽  
Disc Disease ◽  
Degenerative Disc ◽  
Dynamic Instrumentation
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