Characterization of the copper-sensing transcriptional regulator CopR from the hyperthermophilic archeaon Thermococcus onnurineus NA1

BioMetals ◽  
2019 ◽  
Vol 32 (6) ◽  
pp. 923-937
Author(s):  
Seo-Yeon Kim ◽  
Hong Joo Jeong ◽  
Minwook Kim ◽  
Ae Ran Choi ◽  
Min-Sik Kim ◽  
...  
Keyword(s):  
Transcriptional Regulator ◽  
Thermococcus Onnurineus Na1

scholarly journals Identification and Characterization of Inorganic Pyrophosphatase and PAP Phosphatase from Thermococcus onnurineus NA1

2009 ◽  
Vol 191 (10) ◽  
pp. 3415-3419 ◽  
Author(s):  
Hyun Sook Lee ◽  
Yun Jae Kim ◽  
Jung-Hyun Lee ◽  
Sung Gyun Kang
Keyword(s):  
Gene Clusters ◽  
Inorganic Pyrophosphatase ◽  
Thermococcus Onnurineus Na1 ◽  
First Report ◽  
Activation System ◽  
Sulfate Activation ◽  
Pyrococcus Abyssi ◽  
Identification And Characterization ◽  
Hypothetical Genes

ABSTRACT Two hypothetical genes were functionally verified to be a pyrophosphatase and a PAP phosphatase in Thermococcus onnurineus NA1. This is the first report of the pyrophosphatases and the PAP phosphatases being organized in the gene clusters of the sulfate activation system only in T. onnurineus NA1 and “Pyrococcus abyssi.”

scholarly journals Identification and Characterization of OscR, a Transcriptional Regulator Involved in Osmolarity Adaptation in Vibrio cholerae

2009 ◽  
Vol 191 (13) ◽  
pp. 4082-4096 ◽  
Author(s):  
Nicholas J. Shikuma ◽  
Fitnat H. Yildiz
Keyword(s):  
Vibrio Cholerae ◽  
Biofilm Formation ◽  
Transcriptional Regulator ◽  
Dependent Manner ◽  
Genome Wide ◽  
Low Salt ◽  
Adaptation Response ◽  
Matrix Production ◽  
Identification And Characterization

ABSTRACT Vibrio cholerae is a facultative human pathogen. In its aquatic habitat and as it passes through the digestive tract, V. cholerae must cope with fluctuations in salinity. We analyzed the genome-wide transcriptional profile of V. cholerae grown at different NaCl concentrations and determined that the expression of compatible solute biosynthesis and transporter genes, virulence genes, and genes involved in adhesion and biofilm formation is differentially regulated. We determined that salinity modulates biofilm formation, and this response was mediated through the transcriptional regulators VpsR and VpsT. Additionally, a transcriptional regulator controlling an osmolarity adaptation response was identified. This regulator, OscR (osmolarity controlled regulator), was found to modulate the transcription of genes involved in biofilm matrix production and motility in a salinity-dependent manner. oscR mutants were less motile and exhibited enhanced biofilm formation only under low-salt conditions.

scholarly journals Structural and Functional Characterization of a Ketosteroid Transcriptional Regulator ofMycobacterium tuberculosis

2014 ◽  
Vol 290 (2) ◽  
pp. 872-882 ◽  
Author(s):  
Adam M. Crowe ◽  
Peter J. Stogios ◽  
Israël Casabon ◽  
Elena Evdokimova ◽  
Alexei Savchenko ◽  
...  
Keyword(s):  
Functional Characterization ◽  
Transcriptional Regulator ◽  
Ofmycobacterium Tuberculosis

scholarly journals Cloning and characterization of btr, a Bordetella pertussis gene encoding an FNR-like transcriptional regulator.

1993 ◽  
Vol 175 (22) ◽  
pp. 7228-7235 ◽  
Author(s):  
J D Bannan ◽  
M J Moran ◽  
J I MacInnes ◽  
G A Soltes ◽  
R L Friedman
Keyword(s):  
Bordetella Pertussis ◽  
Transcriptional Regulator ◽  
Gene Encoding
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