Inhibition of metastasis in a murine 4T1 breast cancer model by liposomes preventing tumor cell-platelet interactions

2009 ◽  
Vol 27 (1) ◽  
pp. 25-34 ◽  
Author(s):  
Jane Wenzel ◽  
Reiner Zeisig ◽  
Iduna Fichtner
Keyword(s):  
Breast Cancer ◽  
Tumor Cell ◽  
Cancer Model ◽  
Breast Cancer Model ◽  
4T1 Breast Cancer

Genistein induces breast cancer-associated aromatase and stimulates estrogen-dependent tumor cell growth in in vitro breast cancer model

Toxicology ◽  
2011 ◽  
Vol 289 (2-3) ◽  
pp. 67-73 ◽  
Author(s):  
M.B.M. van Duursen ◽  
S.M. Nijmeijer ◽  
E.S. de Morree ◽  
P. Chr. de Jong ◽  
M. van den Berg
Keyword(s):  
Breast Cancer ◽  
Cell Growth ◽  
Tumor Cell ◽  
Tumor Cell Growth ◽  
Cancer Model ◽  
Breast Cancer Model

scholarly journals Theranostic probe for simultaneous in vivo photoacoustic imaging and confined photothermolysis by pulsed laser at 1064 nm in 4T1 breast cancer model

Nanoscale ◽  
2014 ◽  
Vol 6 (24) ◽  
pp. 15228-15235 ◽  
Author(s):  
Min Zhou ◽  
Geng Ku ◽  
Laura Pageon ◽  
Chun Li
Keyword(s):  
Breast Cancer ◽  
Photoacoustic Imaging ◽  
Pulsed Laser ◽  
Tumor Ablation ◽  
Cancer Model ◽  
Single Compartment ◽  
Breast Cancer Model ◽  
Nanoparticle System ◽  
4T1 Breast Cancer

A single-compartment nanoparticle system mediates dual photoacoustic imaging and confined thermolysis for tumor ablation.

Using Computer-based Image Analysis to Improve Quantification of Lung Metastasis in the 4T1 Breast Cancer Model

10.3791/61805 ◽  
2020 ◽  
Author(s):  
Margaret A. Nagai-Singer ◽  
Alissa Hendricks-Wenger ◽  
Rebecca M. Brock ◽  
Holly A. Morrison ◽  
Juselyn D. Tupik ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Image Analysis ◽  
Lung Metastasis ◽  
Cancer Model ◽  
Breast Cancer Model ◽  
Computer Based ◽  
4T1 Breast Cancer

scholarly journals A chaperone protein-enriched tumor cell lysate vaccine generates protective humoral immunity in a mouse breast cancer model

2008 ◽  
Vol 7 (3) ◽  
pp. 721-729 ◽  
Author(s):  
Gang Li ◽  
Samita Andreansky ◽  
Gustavo Helguera ◽  
Marjan Sepassi ◽  
Nona Janikashvili ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Tumor Cell ◽  
Humoral Immunity ◽  
Cancer Model ◽  
Cell Lysate ◽  
Chaperone Protein ◽  
Breast Cancer Model ◽  
Mouse Breast Cancer ◽  
Tumor Cell Lysate

scholarly journals Increased Expression of P-Glycoprotein Is Associated with Doxorubicin Chemoresistance in the Metastatic 4T1 Breast Cancer Model

2011 ◽  
Vol 178 (2) ◽  
pp. 838-852 ◽  
Author(s):  
Lili Bao ◽  
Aliyya Haque ◽  
Kamilah Jackson ◽  
Sidhartha Hazari ◽  
Krzysztof Moroz ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Model ◽  
P Glycoprotein ◽  
Breast Cancer Model ◽  
4T1 Breast Cancer

Genistein induces breast cancer-associated aromatase and stimulates estrogen-dependent tumor cell growth in in vitro breast cancer model

Toxicology ◽  
2011 ◽  
Vol 290 (2-3) ◽  
pp. 145-146
Author(s):  
Majorie B.M. van Duursen ◽  
Evelien E.J.W. Smeets ◽  
Sandra M. Nijmeijer ◽  
Paul Chr de Jong ◽  
Martin van den Berg
Keyword(s):  
Breast Cancer ◽  
Cell Growth ◽  
Tumor Cell ◽  
Tumor Cell Growth ◽  
Cancer Model ◽  
Breast Cancer Model

scholarly journals Osteopontin binds ICOSL promoting tumor metastasis

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Davide Raineri ◽  
Chiara Dianzani ◽  
Giuseppe Cappellano ◽  
Federica Maione ◽  
Gianluca Baldanzi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Tumor Metastasis ◽  
Immune Checkpoints ◽  
Cancer Model ◽  
Therapeutic Approaches ◽  
Breast Cancer Model ◽  
4T1 Breast Cancer ◽  
Anti Tumor Activity

Abstract ICOSL/ICOS are costimulatory molecules pertaining to immune checkpoints; their binding transduces signals having anti-tumor activity. Osteopontin (OPN) is here identified as a ligand for ICOSL. OPN binds a different domain from that used by ICOS, and the binding induces a conformational change in OPN, exposing domains that are relevant for its functions. Here we show that in vitro, ICOSL triggering by OPN induces cell migration, while inhibiting anchorage-independent cell growth. The mouse 4T1 breast cancer model confirms these data. In vivo, OPN-triggering of ICOSL increases angiogenesis and tumor metastatization. The findings shed new light on ICOSL function and indicate that another partner beside ICOS may be involved; they also provide a rationale for developing alternative therapeutic approaches targeting this molecular trio.

The Immunostimulatory Effect of Biogenic Selenium Nanoparticles on the 4T1 Breast Cancer Model: an In Vivo Study

2012 ◽  
Vol 149 (1) ◽  
pp. 22-28 ◽  
Author(s):  
Mohammad Hossein Yazdi ◽  
Mehdi Mahdavi ◽  
Bardia Varastehmoradi ◽  
Mohammad Ali Faramarzi ◽  
Ahmad Reza Shahverdi
Keyword(s):  
Breast Cancer ◽  
Selenium Nanoparticles ◽  
In Vivo Study ◽  
Cancer Model ◽  
Immunostimulatory Effect ◽  
Breast Cancer Model ◽  
4T1 Breast Cancer ◽  
Biogenic Selenium Nanoparticles
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