Vitamin D Deficiency and Corticosteroid Use Are Risk Factors for Low Bone Mineral Density in Inflammatory Bowel Disease Patients

2014 ◽  
Vol 59 (8) ◽  
pp. 1878-1884 ◽  
Author(s):  
Bincy P. Abraham ◽  
Preethi Prasad ◽  
Hoda M. Malaty
Keyword(s):  
Risk Factors ◽  
Bone Mineral Density ◽  
Inflammatory Bowel Disease ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Bone Mineral ◽  
Bowel Disease ◽  
Mineral Density ◽  
Low Bone Mineral Density ◽  
Inflammatory Bowel

scholarly journals LOW BONE MINERAL DENSITY IN INFLAMMATORY BOWEL DISEASE—A STUDY OF THE PREVALENCE AND RISK FACTORS

2003 ◽  
Vol 98 ◽  
pp. S257-S258
Author(s):  
Lawrence W. Comerford ◽  
Stephen J. Bickston ◽  
Kristen Arseneau ◽  
Meredith Gross ◽  
Viktor Bovbjerg ◽  
...  
Keyword(s):  
Risk Factors ◽  
Bone Mineral Density ◽  
Inflammatory Bowel Disease ◽  
Bone Mineral ◽  
Bowel Disease ◽  
Mineral Density ◽  
Low Bone Mineral Density ◽  
Inflammatory Bowel

scholarly journals Analysis of Risk Factors for Low Bone Mineral Density in Inflammatory Bowel Disease

Digestion ◽  
2006 ◽  
Vol 73 (1) ◽  
pp. 40-46 ◽  
Author(s):  
Pascal Frei ◽  
Michael Fried ◽  
Vera Hungerbühler ◽  
Christina Rammert ◽  
Valentin Rousson ◽  
...  
Keyword(s):  
Risk Factors ◽  
Bone Mineral Density ◽  
Inflammatory Bowel Disease ◽  
Bone Mineral ◽  
Bowel Disease ◽  
Mineral Density ◽  
Low Bone Mineral Density ◽  
Inflammatory Bowel

Risk Factors for Low Bone Mineral Density in Children and Adolescents with Inflammatory Bowel Disease

2008 ◽  
Vol 53 (10) ◽  
pp. 2746-2753 ◽  
Author(s):  
Letícia Helena Caldas Lopes ◽  
Vera Lucia Sdepanian ◽  
Vera Lúcia Szejnfeld ◽  
Mauro Batista de Morais ◽  
Ulysses Fagundes-Neto
Keyword(s):  
Risk Factors ◽  
Bone Mineral Density ◽  
Inflammatory Bowel Disease ◽  
Children And Adolescents ◽  
Bone Mineral ◽  
Bowel Disease ◽  
Mineral Density ◽  
Low Bone Mineral Density ◽  
Inflammatory Bowel

scholarly journals Analysis of Risk Factors for Low Bone Mineral Density in Patients with Inflammatory Bowel Disease

2010 ◽  
Vol 55 (4) ◽  
pp. 237 ◽  
Author(s):  
Jae Jung Park ◽  
Sung-Ae Jung ◽  
Young Wook Noh ◽  
Min-Jung Kang ◽  
Ji Min Jung ◽  
...  
Keyword(s):  
Risk Factors ◽  
Bone Mineral Density ◽  
Inflammatory Bowel Disease ◽  
Bone Mineral ◽  
Bowel Disease ◽  
Mineral Density ◽  
Low Bone Mineral Density ◽  
Inflammatory Bowel

scholarly journals Lean mass, magnesium, fecal calprotectin and glucocorticoid exposure as risk factors for low bone mineral density in inflammatory bowel disease patients

2021 ◽  
Author(s):  
Iulia Soare ◽  
Anca Sirbu ◽  
Mircea Mihai Diculescu ◽  
Bogdan Radu Mateescu ◽  
Cristian Tieranu ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Inflammatory Bowel Disease ◽  
Vitamin D ◽  
Bone Mineral ◽  
Lean Mass ◽  
Bowel Disease ◽  
Mineral Density ◽  
Skeletal Muscle Index ◽  
Low Bone Mineral Density ◽  
Inflammatory Bowel

Background and aims: Low bone mineral density (BMD) is a common complication in patients with inflammatory bowel disease (IBD). However, debates are ongoing with regard to the other involved factors, especially in younger patients. This study aimed to evaluate the parameters that contribute to decreased BMD, focusing on premenopausal women and men aged <50 years. Methods: This study has evaluated 81 patients with IBD and 81 age-, sex- and body mass index (BMI)-matched controls. Blood tests were conducted on IBD patients, and dual-energy X-ray absorptiometry (DXA) scan was performed on both groups. Results: Low BMD and fragility fracture were found to be more prevalent in IBD patients than in healthy subjects (49.3% vs 23.4%, p = 0.001 and 9.8% vs 1.2%, p = 0.01, respectively). Patients with low BMD were older, with a longer disease duration, higher faecal calprotectin (FC) level and lower magnesium and lean mass (appreciated as appendicular skeletal muscle index (ASMI)). Multiple regression analysis revealed that ASMI, age and use of glucocorticoids were independent parameters for decreased BMD. Although 91.3% of the patients had a 25-hydroxy vitamin D level of <30 ng/mL, it was not a statistically significant factor for decreased BMD. Conclusion: In our study, the levels of vitamin D did not seem to have an important impact on BMD. Conversely, FC, magnesium and lean mass are important factors, suggesting that good control of disease, adequate magnesium intake and increased lean mass can have a good impact on bone metabolism in patients with IBD.

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