Inhibitory Control in Autism Spectrum Disorders: Meta-analyses on Indirect and Direct Measures

Purpose – Studies have found innate vulnerabilities which potentially may increase the risk of an individual with autism spectrum disorders (ASD) finding themselves involved with the criminal justice system as a result of being charged with a sexual offence. The purpose of this paper is to evaluate the literature which has explored sexual offending in individuals with ASD. Design/methodology/approach – A systematic PRISMA review (PRISMA, Preferred Reporting Items for Systematic Reviews and Meta-Analyses) was conducted using internet-based bibliographic databases (PsycINFO, MEDLINE, Psychology and Behavioural Sciences Collection and PsycARTICLES) in order to access studies which investigated to any degree the association between ASD and sexual offending. Findings – Only a small number of case reports (n=7) on sexual offending in individuals with ASD and a small number of prevalence studies (n=7) were identified. Research limitations/implications – Research is urgently required to identify the specific requirements and needs of sexual offenders with ASD in order to inform an appropriate treatment strategy for successful outcomes. Originality/value – Relatively few studies and reviews have investigated the area of ASD and sexual offending specifically.

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Neural correlates of emotional inhibitory control in autism spectrum disorders

Research in Developmental Disabilities ◽

10.1016/j.ridd.2017.03.008 ◽

2017 ◽

Vol 64 ◽

pp. 64-77 ◽

Cited By ~ 4

Author(s):

Francisco Velasquez ◽

Xiaoyan Angela Qin ◽

Melissa A. Reilly ◽

Emily Neuhaus ◽

Annette Estes ◽

...

Keyword(s):

Autism Spectrum Disorders ◽

Inhibitory Control ◽

Neural Correlates ◽

Autism Spectrum ◽

Spectrum Disorders

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Cesarean section delivery is a risk factor of autism-related behaviors in mice

Scientific Reports ◽

10.1038/s41598-021-88437-8 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Masatoshi Nagano ◽

Fumihito Saitow ◽

Shinpei Higo ◽

Makoto Uzuki ◽

Yasunori Mikahara ◽

...

Keyword(s):

Risk Factor ◽

Autism Spectrum Disorders ◽

Cesarean Section ◽

Autism Spectrum ◽

Causal Association ◽

Wild Type ◽

Cesarean Section Delivery ◽

Life Threatening ◽

Spectrum Disorders ◽

Meta Analyses

AbstractCesarean section (C/S) is one way of delivering babies, and is chosen when mothers or babies are facing problems or life-threatening conditions during pregnancy. Many meta-analyses have suggested an etiological relationship between C/S delivery and autism spectrum disorders (ASDs). However, as a risk factor for ASDs, C/S delivery has not yet been well studied. Because C/S deliveries have been increasing, it is very important to investigate the causal association between C/S and ASDs. Here, using three approaches, we showed experimentally that C/S delivery induced ASD-like traits in offspring mice, and that some of these changes were ameliorated by one-time oxytocin (OXT) treatment. Treatment with OXT receptor antagonists before natural delivery also induced ASD-related behaviors. Moreover, wild-type mice born to OXT-KO dams showed similar changes. Thus, insufficient OXT exposure from dams to offspring during delivery may be a trigger for ASD-related behaviors.

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