scholarly journals Prepotent Response Inhibition and Interference Control in Autism Spectrum Disorders: Two Meta-Analyses

2014 ◽  
Vol 7 (4) ◽  
pp. 407-420 ◽  
Author(s):  
Hilde M. Geurts ◽  
Sanne F. W. M. van den Bergh ◽  
Laura Ruzzano
2013 ◽  
Vol 19 (6) ◽  
pp. 646-655 ◽  
Author(s):  
Petra S. Barneveld ◽  
Leo de Sonneville ◽  
Sophie van Rijn ◽  
Herman van Engeland ◽  
Hanna Swaab

AbstractIn this study, we addressed the relation between specific deficits in cognitive control and schizotypal symptomatology in adolescents with autism spectrum disorders (ASD) diagnosed in childhood. We aimed to identify cognitive control deficits as markers of vulnerability to the development of schizophrenia spectrum pathology in ASD. Symptoms of autism and the risk for schizotypal symptomatology were assessed in 29 high-functioning adolescents with ASD, and compared with 40 typically developing adolescents. Cognitive control (response inhibition, mental flexibility, visuo-motor control, interference control, and perseveration) was evaluated for specific association with schizotypal symptomatology. Impaired response inhibition appeared to be strongly and specifically associated with schizotypal symptomatology in adolescents with ASD, especially those with positive and disorganized symptoms. Response inhibition problems could indicate vulnerability to the development of schizotypal symptomatology in ASD. (JINS, 2013, 19, 1–10)


2019 ◽  
Vol 13 (4) ◽  
pp. 591-602 ◽  
Author(s):  
Li‐juan Shi ◽  
Han‐yu Zhou ◽  
Yan‐mei Shen ◽  
Ya Wang ◽  
Yu‐min Fang ◽  
...  

Purpose – Studies have found innate vulnerabilities which potentially may increase the risk of an individual with autism spectrum disorders (ASD) finding themselves involved with the criminal justice system as a result of being charged with a sexual offence. The purpose of this paper is to evaluate the literature which has explored sexual offending in individuals with ASD. Design/methodology/approach – A systematic PRISMA review (PRISMA, Preferred Reporting Items for Systematic Reviews and Meta-Analyses) was conducted using internet-based bibliographic databases (PsycINFO, MEDLINE, Psychology and Behavioural Sciences Collection and PsycARTICLES) in order to access studies which investigated to any degree the association between ASD and sexual offending. Findings – Only a small number of case reports (n=7) on sexual offending in individuals with ASD and a small number of prevalence studies (n=7) were identified. Research limitations/implications – Research is urgently required to identify the specific requirements and needs of sexual offenders with ASD in order to inform an appropriate treatment strategy for successful outcomes. Originality/value – Relatively few studies and reviews have investigated the area of ASD and sexual offending specifically.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Masatoshi Nagano ◽  
Fumihito Saitow ◽  
Shinpei Higo ◽  
Makoto Uzuki ◽  
Yasunori Mikahara ◽  
...  

AbstractCesarean section (C/S) is one way of delivering babies, and is chosen when mothers or babies are facing problems or life-threatening conditions during pregnancy. Many meta-analyses have suggested an etiological relationship between C/S delivery and autism spectrum disorders (ASDs). However, as a risk factor for ASDs, C/S delivery has not yet been well studied. Because C/S deliveries have been increasing, it is very important to investigate the causal association between C/S and ASDs. Here, using three approaches, we showed experimentally that C/S delivery induced ASD-like traits in offspring mice, and that some of these changes were ameliorated by one-time oxytocin (OXT) treatment. Treatment with OXT receptor antagonists before natural delivery also induced ASD-related behaviors. Moreover, wild-type mice born to OXT-KO dams showed similar changes. Thus, insufficient OXT exposure from dams to offspring during delivery may be a trigger for ASD-related behaviors.


Sign in / Sign up

Export Citation Format

Share Document