Case Report: Autism Risk Within the Context of Two Chromosome 15 Syndromes

ABSTRACTChromosome 15 duplication has been associated with a number of psychiatric illnesses including psychosis and autism. However, literature on association with attention-deficit hyperactivity disorder (ADHD) is scant. This case report describes a patient with chromosome 15 duplication diagnosed with ADHD in our neurodevelopmental clinic. The possible biological underpinnings are discussed along with possible challenges in diagnosis and management. The need for better understanding ADHD as a behavioral phenotype in such cases along with need for tailored management strategies is emphasized.

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Twenty-year cytogenetic and molecular follow-up of a patient with ring chromosome 15: a case report

Journal of Medical Case Reports ◽

10.1186/1752-1947-6-283 ◽

2012 ◽

Vol 6 (1) ◽

Cited By ~ 6

Author(s):

Roberta S Guilherme ◽

Vera de FA Meloni ◽

Sylvia S Takeno ◽

Renata Pellegrino ◽

Decio Brunoni ◽

...

Keyword(s):

Case Report ◽

Ring Chromosome ◽

Chromosome 15

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Cutis tricolor parvimaculata in ring chromosome 15 syndrome: A case report

Pediatric Dermatology ◽

10.1111/pde.13497 ◽

2018 ◽

Vol 35 (3) ◽

pp. e204-e205 ◽

Cited By ~ 1

Author(s):

Cristina Ribeiro Dias Barroso ◽

Leonardo Silveira Gomes ◽

Vinícius Abrantes Silvestre ◽

Claudia Yamada Utagawa

Keyword(s):

Case Report ◽

Ring Chromosome ◽

Chromosome 15

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P-16. PGD for marker chromosome 15: case report

Reproductive BioMedicine Online ◽

10.1016/s1472-6483(12)60099-6 ◽

2002 ◽

Vol 4 ◽

pp. 47

Author(s):

H Berkil ◽

A Biricik ◽

S Kahraman ◽

I Giiney ◽

K Yakin ◽

...

Keyword(s):

Case Report ◽

Marker Chromosome ◽

Chromosome 15 ◽

P 16

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Acute promyelocytic leukemia with a cryptic insertion of RARA into PML on chromosome 15 due to uniparental isodisomy: A case report

Oncology Letters ◽

10.3892/ol.2017.5979 ◽

2017 ◽

Vol 13 (6) ◽

pp. 4180-4184 ◽

Cited By ~ 2

Author(s):

Anna Venci ◽

Rita Mazza ◽

Orietta Spinelli ◽

Luciana Di Schiena ◽

Daniela Bettio

Keyword(s):

Case Report ◽

Acute Promyelocytic Leukemia ◽

Promyelocytic Leukemia ◽

Chromosome 15 ◽

Uniparental Isodisomy

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Ring chromosome 15 – cytogenetics and mapping arrays: a case report and review of the literature

Journal of Medical Case Reports ◽

10.1186/s13256-018-1879-5 ◽

2018 ◽

Vol 12 (1) ◽

Cited By ~ 5

Author(s):

César Paz-y-Miño ◽

Jaime Guevara-Aguirre ◽

Ariane Paz-y-Miño ◽

Francesca Velarde ◽

Isaac Armendáriz-Castillo ◽

...

Keyword(s):

Case Report ◽

Ring Chromosome ◽

Chromosome 15 ◽

Review Of The Literature ◽

Mapping Arrays

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Behavioural management of Prader-Willi syndrome

Irish Journal of Psychological Medicine ◽

10.1017/s0790966700004687 ◽

1998 ◽

Vol 15 (1) ◽

pp. 32-34

Author(s):

Pat Gibbons ◽

Kathryn O'Donoghue

Keyword(s):

Early Childhood ◽

Case Report ◽

Weight Gain ◽

Weight Control ◽

Well Being ◽

Behavioural Problems ◽

Chromosome 15 ◽

Prader Willi Syndrome ◽

Behavioural Management ◽

Genetic Illness

AbstractPrader-Willi syndrome is a genetic illness associated with a defect on chromosome 15. It presents with hypotonicity in infancy followed by voracious appetite and gross obesity from early childhood and with a range of other clinical and behavioural sequelae. This case report is of an adolescent boy who was admitted to a psychiatric unit for an intensive behavioural programme to control his weight gain and deal with associated behavioural problems, and demonstrates that an inpatient programme can lead to sustainable improvements in weight control and other indicators of well-being in PWS patients.

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