Preparation, physicochemical characterization and in vitro dissolution studies of azithromycin-cyclodextrin inclusion complexes

2016 ◽  
Vol 85 (1-2) ◽  
pp. 137-149 ◽  
Author(s):  
Mei-rong Zhao ◽  
Li-sheng Wang ◽  
Hua-wen Liu ◽  
Ya-jing Wang ◽  
Hua Yang
2007 ◽  
Vol 57 (1) ◽  
pp. 47-60 ◽  
Author(s):  
Vivek Sinha ◽  
R. Anitha ◽  
Soma Ghosh ◽  
Rachana Kumria ◽  
Jayant Bhinge ◽  
...  

Physicochemical characterization and in vitro dissolution behaviour of celecoxib-β-cyclodextrin inclusion complexes In this study, attempts were made to investigate the effects of β-cyclodextrin (β-CD) on the aqueous solubility and dissolution rate of celecoxib. Inclusion complexes were prepared by the kneading method and characterized by SEM, NMR, IR, DSC, and X-ray powder diffraction. Dissolution rate of the complexes was significantly greater than that of the corresponding physical mixtures and pure drug, indicating that the formation of inclusion complex increased the solubility of the poorly soluble drug celecoxib.


2008 ◽  
Vol 9 (1) ◽  
pp. 314-321 ◽  
Author(s):  
Mayara M. Doile ◽  
Keila A. Fortunato ◽  
Iára C. Schmücker ◽  
Sacha K. Schucko ◽  
Marcos A.S. Silva ◽  
...  

2009 ◽  
Vol 9 (1) ◽  
pp. 295-300 ◽  
Author(s):  
Roudayna Diab ◽  
Lars P. Jordheim ◽  
Ghania Degobert ◽  
Suzanne Peyrottes ◽  
Christian Périgaud ◽  
...  

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