Preparation and characterization of biodegradable poly(d,l-lactide) and surface-modified bioactive glass composites as bone repair materials

2009 ◽  
Vol 20 (10) ◽  
pp. 1971-1978 ◽  
Author(s):  
Du Juan Zhang ◽  
Li Fang Zhang ◽  
Zuo Chun Xiong ◽  
Wei Bai ◽  
Cheng Dong Xiong
Keyword(s):  
Bioactive Glass ◽  
Bone Repair ◽  
Glass Composites ◽  
Repair Materials ◽  
Biodegradable Poly ◽  
Surface Modified ◽  
Bone Repair Materials

Preparation and characterization of alginate/HACC/oyster shell powder biocomposite scaffolds for potential bone tissue engineering applications

RSC Advances ◽  
2016 ◽  
Vol 6 (42) ◽  
pp. 35577-35588 ◽  
Author(s):  
Tai-ying Chen ◽  
Hao-chao Huang ◽  
Jia-lin Cao ◽  
Yan-jiao Xin ◽  
Wen-feng Luo ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Repair ◽  
Oyster Shell ◽  
Natural Polymers ◽  
Tissue Engineering Scaffolds ◽  
Repair Materials ◽  
Oyster Shell Powder ◽  
Bone Repair Materials ◽  
Shell Powder

Tissue engineering scaffolds combining biominerals and natural polymers are prospective candidates for bone repair materials.

Detailed structure of a new bioactive glass composition for the design of bone repair materials

2017 ◽  
Vol 475 ◽  
pp. 10-14 ◽  
Author(s):  
Ailing Li ◽  
Huihui Ren ◽  
Yang Cui ◽  
Chao Wang ◽  
Xiaojuan Zhou ◽  
...  
Keyword(s):  
Bioactive Glass ◽  
Bone Repair ◽  
Glass Composition ◽  
Detailed Structure ◽  
Repair Materials ◽  
Bone Repair Materials

scholarly journals Strontium-substituted sub-micron bioactive glasses inhibit ostoclastogenesis through suppression of RANKL-induced signaling pathway

2020 ◽  
Vol 7 (3) ◽  
pp. 303-311 ◽  
Author(s):  
Deqiu Huang ◽  
Fujian Zhao ◽  
Wendong Gao ◽  
Xiaofeng Chen ◽  
Zhouyi Guo ◽  
...  
Keyword(s):  
Bioactive Glass ◽  
Signaling Pathway ◽  
Bone Repair ◽  
Superior Performance ◽  
Bioactive Glasses ◽  
Repair Materials ◽  
Potential Impact ◽  
Bone Repair Materials

Abstract Strontium-substituted bioactive glass (Sr-BG) has shown superior performance in bone regeneration. Sr-BG-induced osteogenesis has been extensively studied; however, Sr-BG-mediated osteoclastogenesis and the underlying molecular mechanism remain unclear. It is recognized that the balance of osteogenesis and osteoclastogenesis is closely related to bone repair, and the receptor activators of nuclear factor kappaB ligand (RANKL) signaling pathway plays a key role of in the regulation of osteoclastogenesis. Herein, we studied the potential impact and underling mechanism of strontium-substituted sub-micron bioactive glass (Sr-SBG) on RANKL-induced osteoclast activation and differentiation in vitro. As expected, Sr-SBG inhibited RANKL-mediated osteoclastogenesis significantly with the experimental performance of decreased mature osteoclasts formation and downregulation of osteoclastogenesis-related gene expression. Furthermore, it was found that Sr-SBG might suppress osteoclastogenesis by the combined effect of strontium and silicon released through inhibition of RANKL-induced activation of p38 and NF-κB pathway. These results elaborated the effect of Sr-SBG-based materials on osteoclastogenesis through RANKL-induced downstream pathway and might represent a significant guidance for designing better bone repair materials.

Characterization of carbon nanotube (MWCNT) containing P(3HB)/bioactive glass composites for tissue engineering applications

2010 ◽  
Vol 6 (3) ◽  
pp. 735-742 ◽  
Author(s):  
Superb K. Misra ◽  
F. Ohashi ◽  
Sabeel P. Valappil ◽  
Jonathan C. Knowles ◽  
I. Roy ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Carbon Nanotube ◽  
Bioactive Glass ◽  
Engineering Applications ◽  
Glass Composites

Peptide‐modified bone repair materials: Factors influencing osteogenic activity

2019 ◽  
Vol 107 (7) ◽  
pp. 1491-1512 ◽  
Author(s):  
Jie Liao ◽  
Shuai Wu ◽  
Kun Li ◽  
Yubo Fan ◽  
Nicholas Dunne ◽  
...  
Keyword(s):  
Bone Repair ◽  
Osteogenic Activity ◽  
Factors Influencing ◽  
Repair Materials ◽  
Bone Repair Materials
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