scholarly journals Hemocompatibility of styrenic block copolymers for use in prosthetic heart valves

2015 ◽  
Vol 27 (2) ◽  
Author(s):  
Jacob Brubert ◽  
Stefanie Krajewski ◽  
Hans Peter Wendel ◽  
Sukumaran Nair ◽  
Joanna Stasiak ◽  
...  
Keyword(s):  
Block Copolymers ◽  
Heart Valves ◽  
Prosthetic Heart Valves

A real time SAXS study of oriented block copolymers during fast cyclical deformation, with potential application for prosthetic heart valves

Soft Matter ◽  
2011 ◽  
Vol 7 (24) ◽  
pp. 11475 ◽  
Author(s):  
Joanna Stasiak ◽  
Adriano Zaffora ◽  
Maria Laura Costantino ◽  
Geoff D. Moggridge
Keyword(s):  
Block Copolymers ◽  
Real Time ◽  
Potential Application ◽  
Heart Valves ◽  
Prosthetic Heart Valves

ENGINEERING ORIENTATION IN BLOCK COPOLYMERS FOR APPLICATION TO PROSTHETIC HEART VALVES

2010 ◽  
Vol 03 (04) ◽  
pp. 249-252 ◽  
Author(s):  
JOANNA STASIAK ◽  
GEOFF D. MOGGRIDGE ◽  
ADRIANO ZAFFORA ◽  
ANNA PANDOLFI ◽  
MARIA L. COSTANTINO
Keyword(s):  
Mechanical Properties ◽  
Block Copolymer ◽  
Block Copolymers ◽  
Long Range ◽  
Heart Valves ◽  
Mechanical Response ◽  
Mechanical Performance ◽  
Prosthetic Heart Valves ◽  
Anisotropic Mechanical Properties ◽  
Butadiene Styrene

This study demonstrates how the mechanical performance of polymeric material can be enhanced by morphology and phase orientation of block copolymers to achieve desired anisotropic mechanical properties. The material used was a new Kraton block copolymer consisting of styrene-isoprene-butadiene-styrene blocks having cylindrical morphology. We report a method of achieving long range uniaxial as well as biaxial orientation of block copolymer. Each microstructural organization results in a specific mechanical performance, which depends on the direction of the applied deformation. The method of tailoring mechanical properties by engineering microstructure may be successfully utilized to applications requiring anisotropic mechanical response, such as prosthetic heart valves.

The Effect of Dipyridamole and RA 233 on Human Platelet Function in Vitro

1973 ◽  
Vol 29 (03) ◽  
pp. 694-700 ◽  
Author(s):  
Paul L. Rifkin ◽  
Marjorie B. Zucker
Keyword(s):  
Mechanism Of Action ◽  
Human Blood ◽  
Glass Bead ◽  
Heart Valves ◽  
Human Platelet ◽  
Drug Effects ◽  
Simple Relation ◽  
Prosthetic Heart Valves ◽  
Induced Aggregation

SummaryDipyridamole (Persantin) is reported to prolong platelet survival and inhibit embolism in patients with prosthetic heart valves, but its mechanism of action is unknown. Fifty jxM dipyridamole failed to reduce the high percentage of platelets retained when heparinized human blood was passed through a glass bead column, but prolonged the inhibition of retention caused by disturbing blood in vitro. Possibly the prostheses act like disturbance. Although RA 233 was as effective as dipyridamole in inhibiting the return of retention, it was less effective in preventing the uptake of adenosine into erythrocytes, and more active in inhibiting ADP-induced aggregation and release. Thus there is no simple relation between these drug effects.

Erythrocyte Destruction by Prosthetic Heart Valves

Circulation ◽  
1968 ◽  
Vol 37 (4s2) ◽  
Author(s):  
ROBERT A. INDEGLIA ◽  
MICHAEL A. SHEA ◽  
RICHARD L. VARCO ◽  
EUGENE F. BERNSTEIN
Keyword(s):  
Heart Valves ◽  
Prosthetic Heart Valves ◽  
Erythrocyte Destruction

Local Anticoagulation of Prosthetic Heart Valves

Circulation ◽  
1973 ◽  
Vol 48 (1s3) ◽  
Author(s):  
MICHAEL L. SCHWARTZ ◽  
DEAN SHELDON ◽  
FRANK DORMAN ◽  
PERRY L. BLACKSHEAR ◽  
RICHARD L. VARCO ◽  
...  
Keyword(s):  
Heart Valves ◽  
Prosthetic Heart Valves

scholarly journals Ultra slow thrombolysis in dysfunctional prosthetic heart valves, a controversial technique in critically ill patients not candidates for surgery

2019 ◽  
Vol 25 ◽  
pp. 100421
Author(s):  
Noel Alberto Flórez ◽  
German Camilo Giraldo ◽  
Julian David Yara ◽  
Stephania Galindo-Coral ◽  
Juan David López ◽  
...  
Keyword(s):  
Critically Ill ◽  
Critically Ill Patients ◽  
Heart Valves ◽  
Prosthetic Heart Valves

scholarly journals Warfarin poisoning in patients with prosthetic heart valves.

BMJ ◽  
1981 ◽  
Vol 283 (6291) ◽  
pp. 581-582 ◽  
Author(s):  
F Toolis ◽  
R H Robson ◽  
J A Critchley
Keyword(s):  
Heart Valves ◽  
Prosthetic Heart Valves
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