Enhancing osseointegration of titanium implants through large-grit sandblasting combined with micro-arc oxidation surface modification

Abstract The micro-arc oxidation method was applied to modify the surface of 3D printed titanium implants with a complex internal structure. Two different electrolyte solutions were used for thesurface modification, for which the respective working parameters of the micro-arc oxidation process were developed. Surface coatings formed with these parameters on the 3D implants have the same chemical composition and have the same surface morphology as surface coatings on 2D substrates. The measurement of the coating thickness using the X-ray microtomography demonstrates that this method is a useful tool for the thickness control of porous surface coatings at the inside and outside of the 3D titanium implants.

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Taking Hydroxyapatite-Coated Titanium Implants Two Steps Forward: Surface Modification Using Graphene Mesolayers and a Hydroxyapatite-Reinforced Polymeric Scaffold

ACS Biomaterials Science & Engineering ◽

10.1021/acsbiomaterials.0c01105 ◽

2020 ◽

Author(s):

A. M. Fathi ◽

M. K. Ahmed ◽

M. Afifi ◽

A. A. Menazea ◽

Vuk Uskoković

Keyword(s):

Surface Modification ◽

Titanium Implants ◽

Polymeric Scaffold

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Influence of surface modification of titanium implants on improving osseointegration: An in vitro study

Journal of Prosthetic Dentistry ◽

10.1016/j.prosdent.2021.06.034 ◽

2021 ◽

Author(s):

Mohini Gajiwala ◽

Jyoti Paliwal ◽

Syed Yawer Husain ◽

Ashish Dadarwal ◽

Rajni Kalla ◽

...

Keyword(s):

Surface Modification ◽

In Vitro Study ◽

Titanium Implants ◽

Vitro Study ◽

Modification Of Titanium

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Directed Irradiation Synthesis as an Advanced Plasma Technology for Surface Modification to Activate Porous and “as-received” Titanium Surfaces

Metals ◽

10.3390/met9121349 ◽

2019 ◽

Vol 9 (12) ◽

pp. 1349 ◽

Cited By ~ 3

Author(s):

Ana Civantos ◽

Jean Paul Allain ◽

Juan Jose Pavón ◽

Akshath Shetty ◽

Osman El-Atwani ◽

...

Keyword(s):

Contact Angle ◽

Surface Modification ◽

Titanium Implants ◽

Lower Percentage ◽

Force Microscopy ◽

Atomic Force ◽

Titanium Surfaces ◽

Singly Charged ◽

Biological Performance

For the design of smart titanium implants, it is essential to balance the surface properties without any detrimental effect on the bulk properties of the material. Therefore, in this study, an irradiation-driven surface modification called directed irradiation synthesis (DIS) has been developed to nanopattern porous and “as-received” c.p. Ti surfaces with the aim of improving cellular viability. Nanofeatures were developed using singly-charged argon ions at 0.5 and 1.0 keV energies, incident angles from 0° to 75° degrees, and fluences up to 5.0 × 1017 cm−2. Irradiated surfaces were evaluated by scanning electron microscopy, atomic force microscopy and contact angle, observing an increased hydrophilicity (a contact angle reduction of 73.4% and 49.3%) and a higher roughness on both surfaces except for higher incident angles, which showed the smoothest surface. In-vitro studies demonstrated the biocompatibility of directed irradiation synthesis (DIS) reaching 84% and 87% cell viability levels at 1 and 7 days respectively, and a lower percentage of damaged DNA in tail compared to the control c.p. Ti. All these results confirm the potential of the DIS technique to modify complex surfaces at the nanoscale level promoting their biological performance.

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