Physiological aspects of the mitochondrial cyclosporin A-insensitive palmitate/Ca2+-induced pore: tissue specificity, age profile and dependence on the animal’s adaptation to hypoxia

2009 ◽  
Vol 41 (4) ◽  
pp. 395-401 ◽  
Author(s):  
Konstantin N. Belosludtsev ◽  
Nils-Erik L. Saris ◽  
Natalia V. Belosludtseva ◽  
Alexander S. Trudovishnikov ◽  
Lyudmila D. Lukyanova ◽  
...  
Keyword(s):  
Cyclosporin A ◽  
Tissue Specificity ◽  
Adaptation To Hypoxia ◽  
Age Profile

The Hierarchic Order of Intermediate Filament Structure and Assembly

1985 ◽  
Vol 43 ◽  
pp. 722-725
Author(s):  
U. Aebi ◽  
E.C. Glavaris ◽  
R. Eichner
Keyword(s):  
Tissue Specificity ◽  
Structural Model ◽  
Eukaryotic Cells ◽  
Cdna Sequencing ◽  
Filament Structure ◽  
Keratin Filaments ◽  
Isoelectric Points ◽  
Immunological Crossreactivity

Five different classes of intermediate-sized filaments (IFs) have been identified in differentiated eukaryotic cells: vimentin in mesenchymal cells, desmin in muscle cells, neurofilaments in nerve cells, glial filaments in glial cells and keratin filaments in epithelial cells. Despite their tissue specificity, all IFs share several common attributes, including immunological crossreactivity, similar morphology (e.g. about 10 nm diameter - hence ‘10-nm filaments’) and the ability to reassemble in vitro from denatured subunits into filaments virtually indistinguishable from those observed in vivo. Further more, despite their proteinchemical heterogeneity (their MWs range from 40 kDa to 200 kDa and their isoelectric points from about 5 to 8), protein and cDNA sequencing of several IF polypeptides (for refs, see 1,2) have provided the framework for a common structural model of all IF subunits.

Magnetic resonance imaging of renal transplants: its value in the differentiation of acute rejection and cyclosporin a nephrotoxicity

1988 ◽  
Vol 39 (2) ◽  
pp. 220-228
Author(s):  
L TESTRAKE ◽  
L SCHULTZEKOOL ◽  
L PAUL ◽  
A TEGZESS ◽  
J WEENINGS ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Acute Rejection ◽  
Cyclosporin A ◽  
Resonance Imaging ◽  
Renal Transplants

1869: Combined Therapy of FR167653 and Cyclosporin A Significantly Prolonged Animal Survival in ratRenal Allografts

2004 ◽  
Vol 171 (4S) ◽  
pp. 493-494
Author(s):  
Haruhito Azuma ◽  
Shiro Takahara ◽  
Takashi Wada ◽  
Takeshi Sakamoto ◽  
Akihiko Okuyama ◽  
...  
Keyword(s):  
Cyclosporin A ◽  
Combined Therapy ◽  
Animal Survival
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