Curcumin Loaded Fe3O4 Nanoparticles: An MRI Contrast Agent to Investigate the Impact of Curcumin on Maximizing Negative Contrast and r2 Relaxation Rate

2018 ◽  
Vol 28 (5) ◽  
pp. 2169-2178 ◽  
Author(s):  
Milad Ghorbaanee ◽  
Amir Ahmad Salarian ◽  
Valiallah Saba
Keyword(s):  
Contrast Agent ◽  
Relaxation Rate ◽  
Fe3o4 Nanoparticles ◽  
Negative Contrast ◽  
Mri Contrast Agent ◽  
Mri Contrast ◽  
The Impact

Magnetic Fe3O4 nanoparticles coated by natural rubber latex as MRI contrast agent

2019 ◽  
Vol 475 ◽  
pp. 458-464 ◽  
Author(s):  
Soudabeh Arsalani ◽  
Eder J. Guidelli ◽  
Matheus A. Silveira ◽  
Carlos E.G. Salmon ◽  
Jefferson F.D.F. Araujo ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Natural Rubber ◽  
Fe3o4 Nanoparticles ◽  
Natural Rubber Latex ◽  
Mri Contrast Agent ◽  
Rubber Latex ◽  
Mri Contrast ◽  
Magnetic Fe3o4 Nanoparticles ◽  
Magnetic Fe3o4

Preparation and characterization of PVPI-coated Fe3O4 nanoparticles as an MRI contrast agent

2013 ◽  
Vol 340 ◽  
pp. 57-60 ◽  
Author(s):  
Guangshuo Wang ◽  
Ying Chang ◽  
Ling Wang ◽  
Zhiyong Wei ◽  
Jianyun Kang ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Fe3o4 Nanoparticles ◽  
Mri Contrast Agent ◽  
Mri Contrast

Preparation and Imaging Study of Tumor-targeting MRI Contrast Agent Based on Fe3O4 Nanoparticles

2015 ◽  
Vol 44 (12) ◽  
pp. 1771-1773 ◽  
Author(s):  
Wan’er Chen ◽  
Yuxin Han ◽  
Yu’e Qian ◽  
Jianbin Tang ◽  
Hongjie Hu ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Fe3o4 Nanoparticles ◽  
Tumor Targeting ◽  
Imaging Study ◽  
Mri Contrast Agent ◽  
Mri Contrast ◽  
Agent Based

scholarly journals Gadolinium-based MRI contrast agent for the detection of tyrosinase

The Analyst ◽  
2020 ◽  
Vol 145 (4) ◽  
pp. 1169-1173
Author(s):  
Hyewon Seo ◽  
Heather A. Clark
Keyword(s):  
Contrast Agent ◽  
Relaxation Rate ◽  
Cerebral Spinal Fluid ◽  
Spinal Fluid ◽  
Mri Contrast Agent ◽  
Mri Contrast

We successfully designed and synthesized a tyrosinase-targeting Gd(iii)-based MR contrast agent. The probe shows enhanced T1 relaxation rate in the presence of tyrosinase in artificial cerebral spinal fluid.

Synthesis of PVP-coated ultra-small Fe3O4 nanoparticles as a MRI contrast agent

2010 ◽  
Vol 21 (4) ◽  
pp. 1205-1210 ◽  
Author(s):  
Ying Zhang ◽  
Jing-Ying Liu ◽  
Song Ma ◽  
Ya-Jing Zhang ◽  
Xiang Zhao ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Fe3o4 Nanoparticles ◽  
Mri Contrast Agent ◽  
Mri Contrast

scholarly journals New Class of Efficient T2 Magnetic Resonance Imaging Contrast Agent: Carbon-Coated Paramagnetic Dysprosium Oxide Nanoparticles

2020 ◽  
Vol 13 (10) ◽  
pp. 312
Author(s):  
Huan Yue ◽  
Ji Ae Park ◽  
Son Long Ho ◽  
Mohammad Yaseen Ahmad ◽  
Hyunsil Cha ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Magnetic Moments ◽  
Negative Contrast ◽  
Mri Contrast Agents ◽  
Proton Spin ◽  
Mri Contrast Agent ◽  
Water Proton ◽  
Dysprosium Oxide ◽  
Mri Contrast ◽  
T2 Mri

Nanoparticles are considered potential candidates for a new class of magnetic resonance imaging (MRI) contrast agents. Negative MRI contrast agents require high magnetic moments. However, if nanoparticles can exclusively induce transverse water proton spin relaxation with negligible induction of longitudinal water proton spin relaxation, they may provide negative contrast MR images despite having low magnetic moments, thus acting as an efficient T2 MRI contrast agent. In this study, carbon-coated paramagnetic dysprosium oxide (DYO@C) nanoparticles (core = DYO = DyxOy; shell = carbon) were synthesized to explore their potential as an efficient T2 MRI contrast agent at 3.0 T MR field. Since the core DYO nanoparticles have an appreciable (but not high) magnetic moment that arises from fast 4f-electrons of Dy(III) (6H15/2), the DYO@C nanoparticles exhibited an appreciable transverse water proton spin relaxivity (r2) with a negligible longitudinal water proton spin relaxivity (r1). Consequently, they acted as a very efficient T2 MRI contrast agent, as proven from negative contrast enhancements seen in the in vivo T2 MR images.

The Impact of Rigidity and Water Exchange on the Relaxivity of a Dendritic MRI Contrast Agent

2002 ◽  
Vol 8 (5) ◽  
pp. 1040 ◽  
Author(s):  
Gaëlle M. Nicolle ◽  
Éva Tóth ◽  
Heribert Schmitt-Willich ◽  
Bernd Radüchel ◽  
André E. Merbach
Keyword(s):  
Contrast Agent ◽  
Water Exchange ◽  
Mri Contrast Agent ◽  
Mri Contrast ◽  
The Impact

scholarly journals Evaluation of non-targeting, C- or N-pH (low) insertion peptide modified superparamagnetic iron oxide nanoclusters for selective MRI of liver tumors and their potential toxicity in cirrhosis

RSC Advances ◽  
2019 ◽  
Vol 9 (25) ◽  
pp. 14051-14059
Author(s):  
Abdulrahman Ahmed Mahmood ◽  
Jianqi Zhang ◽  
Rufang Liao ◽  
Xiwei Pan ◽  
Dan Xu ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Liver Cancer ◽  
Contrast Agent ◽  
Cancer Diagnosis ◽  
Liver Tumors ◽  
Superparamagnetic Iron Oxide ◽  
Mri Contrast Agent ◽  
Potential Toxicity ◽  
Mri Contrast ◽  
Specific Enhancement

The acid-responsive pHLIP modified SPION as an MRI contrast agent for liver cancer diagnosis requires the validation of both the tumor-specific enhancement and a safe profile in cirrhosis.

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