Scale-up of a physiologically-based pharmacokinetic model to predict the disposition of monoclonal antibodies in monkeys

Journal of Pharmacokinetics and Pharmacodynamics ◽

10.1007/s10928-015-9444-y ◽

2015 ◽

Vol 42 (5) ◽

pp. 527-540 ◽

Author(s):

Patrick M. Glassman ◽

Yang Chen ◽

Joseph P. Balthasar

Keyword(s):

Monoclonal Antibodies ◽

Pharmacokinetic Model ◽

Scale Up ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Development and application of a physiologically based pharmacokinetic model for entrectinib in rats and scale-up to humans: Route-dependent gut wall metabolism

Biomedicine & Pharmacotherapy ◽

10.1016/j.biopha.2021.112520 ◽

2022 ◽

Vol 146 ◽

pp. 112520

Author(s):

Seong-Wook Seo ◽

Dong-Gyun Han ◽

Eugene Choi ◽

Taeuk Park ◽

Jong Hyuk Byun ◽

...

Keyword(s):

Pharmacokinetic Model ◽

Scale Up ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Development of a physiologically-based pharmacokinetic model for ocular disposition of monoclonal antibodies in rabbits

Journal of Pharmacokinetics and Pharmacodynamics ◽

10.1007/s10928-020-09713-0 ◽

2020 ◽

Vol 47 (6) ◽

pp. 597-612 ◽

Author(s):

David Bussing ◽

Dhaval K. Shah

Keyword(s):

Monoclonal Antibodies ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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A Physiologically Based Pharmacokinetic Model of Zidovudine (AZT) in the Mouse: Model Development and Scale-Up to Humans

Journal of Pharmaceutical Sciences ◽

10.1021/js970243y ◽

1997 ◽

Vol 86 (11) ◽

pp. 1223-1228 ◽

Author(s):

Hsiao-Hui Chow

Keyword(s):

Mouse Model ◽

Pharmacokinetic Model ◽

Scale Up ◽

Model Development ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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A Whole-Body Physiologically Based Pharmacokinetic Model of Gefitinib in Mice and Scale-Up to Humans

The AAPS Journal ◽

10.1208/s12248-015-9836-3 ◽

2015 ◽

Vol 18 (1) ◽

pp. 228-238 ◽

Author(s):

Youwei Bi ◽

Jiexin Deng ◽

Daryl J. Murry ◽

Guohua An

Keyword(s):

Pharmacokinetic Model ◽

Scale Up ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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A Physiologically Based Pharmacokinetic Model of Mitoxantrone in Mice and Scale-up to Humans: a Semi-Mechanistic Model Incorporating DNA and Protein Binding

The AAPS Journal ◽

10.1208/s12248-012-9344-7 ◽

2012 ◽

Vol 14 (2) ◽

pp. 352-364 ◽

Author(s):

Guohua An ◽

Marilyn E. Morris

Keyword(s):

Protein Binding ◽

Pharmacokinetic Model ◽

Mechanistic Model ◽

Scale Up ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Integration of Ontogeny Into a Physiologically Based Pharmacokinetic Model for Monoclonal Antibodies in Premature Infants

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1540 ◽

2019 ◽

Vol 60 (4) ◽

pp. 466-476 ◽

Author(s):

Paul R. V. Malik ◽

Andrea N. Edginton

Keyword(s):

Monoclonal Antibodies ◽

Premature Infants ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Second-generation minimal physiologically-based pharmacokinetic model for monoclonal antibodies

Journal of Pharmacokinetics and Pharmacodynamics ◽

10.1007/s10928-013-9332-2 ◽

2013 ◽

Vol 40 (5) ◽

pp. 597-607 ◽

Author(s):

Yanguang Cao ◽

Joseph P. Balthasar ◽

William J. Jusko

Keyword(s):

Monoclonal Antibodies ◽

Pharmacokinetic Model ◽

Second Generation ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Incorporating target-mediated drug disposition in a minimal physiologically-based pharmacokinetic model for monoclonal antibodies

Journal of Pharmacokinetics and Pharmacodynamics ◽

10.1007/s10928-014-9372-2 ◽

2014 ◽

Vol 41 (4) ◽

pp. 375-387 ◽

Author(s):

Yanguang Cao ◽

William J. Jusko

Keyword(s):

Monoclonal Antibodies ◽

Pharmacokinetic Model ◽

Drug Disposition ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Target Mediated Drug Disposition ◽

Physiologically Based

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Preliminary Physiologically Based Pharmacokinetic Model for Cocaine in the Rat: Model Development and Scale-Up to Humans

Journal of Pharmaceutical Sciences ◽

10.1021/js950437i ◽

1996 ◽

Vol 85 (8) ◽

pp. 878-883 ◽

Author(s):

Peter L. Bonatex ◽

Alan Swann ◽

Peter B. Silverman

Keyword(s):

Rat Model ◽

Pharmacokinetic Model ◽

Scale Up ◽

Model Development ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically based pharmacokinetic model development for trazodone: application to paediatric dose projection

10.26226/morressier.5971be87d462b80290b534f2 ◽

2017 ◽

Author(s):

F. Calisti

Keyword(s):

Pharmacokinetic Model ◽

Model Development ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Paediatric Dose

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