scholarly journals Developmental Pathways from Genetic, Prenatal, Parenting and Emotional/Behavioral Risk to Cortisol Reactivity and Adolescent Substance Use: A TRAILS Study

2019 ◽  
Vol 49 (1) ◽  
pp. 17-31
Author(s):  
Kristine Marceau ◽  
Leslie A. Brick ◽  
Valerie S. Knopik ◽  
S. A. Reijneveld
Keyword(s):  
Substance Use ◽  
Developmental Pathways ◽  
Adolescent Substance Use ◽  
Behavioral Risk ◽  
Cortisol Reactivity ◽  
Adolescent Substance

scholarly journals Developmental Pathways from Parental Socioeconomic Status to Adolescent Substance Use: Alternative and Complementary Reinforcement

2017 ◽  
Vol 47 (2) ◽  
pp. 334-348 ◽  
Author(s):  
Jungeun Olivia Lee ◽  
Junhan Cho ◽  
Yoewon Yoon ◽  
Mariel S. Bello ◽  
Rubin Khoddam ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Substance Use ◽  
Developmental Pathways ◽  
Adolescent Substance Use ◽  
Adolescent Substance ◽  
Parental Socioeconomic Status

Interactions between Genetic, Prenatal, Cortisol, and Parenting Influences on Adolescent Substance Use and Frequency: A TRAILS Study

2021 ◽  
pp. 1-10
Author(s):  
Kristine Marceau ◽  
Leslie A. Brick ◽  
Joëlle A. Pasman ◽  
Valerie S. Knopik ◽  
Sijmen A. Reijneveld
Keyword(s):  
Substance Use ◽  
Genetic Risk ◽  
Adolescent Substance Use ◽  
Cortisol Reactivity ◽  
Adolescent Substance ◽  
Polygenic Risk ◽  
Prenatal Risk ◽  
Frequent Use ◽  
Parenting Influences ◽  
Prospective Longitudinal

<b><i>Introduction:</i></b> Dynamic relations between genetic, hormone, and pre- and postnatal environments are theorized as critically important for adolescent substance use but are rarely tested in multifactorial models. This study assessed the impact of interactions of genetic risk and cortisol reactivity with prenatal and parenting influences on both any and frequency of adolescent substance use. <b><i>Methods:</i></b> Data are from the TRacking Adolescents’ Individual Lives Survey (TRAILS), a prospective longitudinal, multi-rater study of 2,230 Dutch adolescents. Genetic risk was assessed via 3 substance-specific polygenic scores. Mothers retrospectively reported prenatal risk when adolescents were 11 years old. Adolescents rated their parents’ warmth and hostility at age 11. Salivary cortisol reactivity was measured in response to a social stress task at age 16. Adolescents’ self-reported cigarette, alcohol, and cannabis use frequency at age 16. <b><i>Results:</i></b> A multivariate hurdle regression model showed that polygenic risk for smoking, alcohol, and cannabis predicted any use of each substance, respectively, but predicted more frequent use only for smoking. Blunted cortisol reactivity predicted any use and more frequent use for all 3 outcomes. There were 2 interactions: blunted cortisol reactivity exacerbated the association of polygenic risk with any smoking and the association of prenatal risk with any alcohol use. <b><i>Conclusion:</i></b> Polygenic risk seems of importance for early use but less so for frequency of use, whereas blunted cortisol reactivity was correlated with both. Blunted cortisol reactivity may also catalyze early risks for substance use, though to a limited degree. Gene-environment interactions play no role in the context of this multifactorial model.

scholarly journals Adolescent Substance Use & Psychopathology: Interactive Effects of Cortisol Reactivity and Emotion Regulation

2015 ◽  
Vol 40 (3) ◽  
pp. 368-380 ◽  
Author(s):  
Jennifer A. Poon ◽  
Caitlin C. Turpyn ◽  
Amysue Hansen ◽  
Juliana Jacangelo ◽  
Tara M. Chaplin
Keyword(s):  
Substance Use ◽  
Emotion Regulation ◽  
Interactive Effects ◽  
Adolescent Substance Use ◽  
Cortisol Reactivity ◽  
Adolescent Substance

Adolescent Substance Use Screening Integrated With Electronic Medical Records

2014 ◽  
Author(s):  
C. McKenna ◽  
B. Gaines ◽  
C. Hatfield ◽  
S. Helman ◽  
L. Meyer ◽  
...  
Keyword(s):  
Substance Use ◽  
Electronic Medical Records ◽  
Medical Records ◽  
Adolescent Substance Use ◽  
Adolescent Substance

Effects of timing of parental alcoholism on adolescent substance use

2013 ◽  
Author(s):  
A. M. Hussong ◽  
W. Huang ◽  
D. Serrano ◽  
P. J. Curran ◽  
L. Chassin
Keyword(s):  
Substance Use ◽  
Adolescent Substance Use ◽  
Parental Alcoholism ◽  
Adolescent Substance
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