Influence of amorphous block on the thermal behavior of well-defined block copolymers based on ε-caprolactone

2012 ◽  
Vol 112 (3) ◽  
pp. 1277-1287 ◽  
Author(s):  
Mario D. Ninago ◽  
Angel J. Satti ◽  
Andrés E. Ciolino ◽  
Marcelo A. Villar
Keyword(s):  
Block Copolymers ◽  
Thermal Behavior ◽  
Amorphous Block

Structural change with blending of crystalline/amorphous block copolymers having different types of microphase separations

Polymer ◽  
2011 ◽  
Vol 52 (26) ◽  
pp. 6146-6153 ◽  
Author(s):  
Masaki Kakiage ◽  
Miho Sekiya ◽  
Takeshi Yamanobe ◽  
Hiroki Uehara
Keyword(s):  
Structural Change ◽  
Block Copolymers ◽  
Amorphous Block ◽  
Different Types

Synthesis and Thermal Behavior of Polyamide 12,T Random and Block Copolymers

2012 ◽  
Vol 313-314 (1) ◽  
pp. 90-99 ◽  
Author(s):  
Theodore F. Novitsky ◽  
Lon J. Mathias ◽  
Scott Osborn ◽  
Roger Ayotte ◽  
Steven Manning
Keyword(s):  
Block Copolymers ◽  
Thermal Behavior ◽  
Polyamide 12

scholarly journals Self-Assembled Nanostructures of Red Fluorescent Amphiphilic Block Copolymers as Both Imaging Probes and Drug Carriers

Polymers ◽  
2018 ◽  
Vol 10 (10) ◽  
pp. 1120 ◽  
Author(s):  
Shuo Huang ◽  
Xin Wei ◽  
Mingfeng Wang
Keyword(s):  
Block Copolymers ◽  
Drug Loading ◽  
Drug Carriers ◽  
Amphiphilic Block Copolymers ◽  
Intracellular Release ◽  
Transmission Electron ◽  
Amorphous Block ◽  
Covalently Bonded ◽  
Imaging Probes ◽  
Self Assembled

We report a red-fluorescent drug delivery system formed by biodegradable and biocompatible amphiphilic A-B-A block copolymers. Each polymer consists of a red fluorescent dye covalently bonded in the middle of hydrophobic block (B) of polylactone, tethered at both ends with poly[(oligo ethylene glycol) methyl ether methacrylate] (POEGMA) as the hydrophilic block. Two types of polylactones, i.e., semicrystalline poly(ε-caprolactone) (PCL) and amorphous poly(δ-decalactone) (PDL), respectively, were incorporated as the hydrophobic segment in the block copolymers. Using transmission electron microscopy, we characterized the self-assembled nanostructures formed by these amphiphilic block copolymers in mixtures of water/tetrahydrofuran or water/dimethylformamide. All of these polymers remained highly fluorescent in water, although some extent of aggregation-induced fluorescence quenching was still observed. Among the three types of polymers presented here, the polymer (RPO-3) containing an amorphous block of PDL showed the highest drug-loading capacity and the largest extent of drug release in acidic media. RPO-3 micelles loaded with doxorubicin as a model of anticancer drug showed sustainable intracellular release and cytotoxicity against HeLa cells.

Synthesis and thermal behavior of liquid-crystalline block copolymers containing both main-chain and side-chain mesomorphic blocks

1994 ◽  
Vol 195 (6) ◽  
pp. 2247-2260 ◽  
Author(s):  
Giancarlo Galli ◽  
Emo Chiellini ◽  
Michele Laus ◽  
Maria Chiara Bignozzi ◽  
Annino Sante Angeloni ◽  
...  
Keyword(s):  
Block Copolymers ◽  
Thermal Behavior ◽  
Liquid Crystalline ◽  
Main Chain ◽  
Side Chain

Preparation of Discotic Liquid Crystal/Amorphous Block Copolymers and Evidence for Microphase Separated Amorphous/LC Structure

2003 ◽  
Vol 36 (9) ◽  
pp. 3432-3435 ◽  
Author(s):  
Olga A. Otmakhova ◽  
Sergei A. Kuptsov ◽  
Raisa V. Talroze ◽  
Timothy E. Patten
Keyword(s):  
Liquid Crystal ◽  
Block Copolymers ◽  
Discotic Liquid Crystal ◽  
Amorphous Block
Sign in / Sign up

Export Citation Format

Share Document