Preparation, characterization and transfection efficacy of chitosan nanoparticles containing the intestinal trefoil factor gene

2011 ◽  
Vol 39 (2) ◽  
pp. 945-952 ◽  
Author(s):  
Yong Sun ◽  
Shuai Zhang ◽  
Xi Peng ◽  
Zhenyu Gong ◽  
Xiaolu Li ◽  
...  
Keyword(s):  
Chitosan Nanoparticles ◽  
Trefoil Factor ◽  
Intestinal Trefoil Factor ◽  
Factor Gene ◽  
Transfection Efficacy

scholarly journals Intestinal Trefoil Factor Gene Expression in Intestinal Epithelial Cells Is Not Regulated by Glucocorticoids

1999 ◽  
Vol 45 (4, Part 2 of 2) ◽  
pp. 208A-208A
Author(s):  
Jing Lin ◽  
Ian R Holzman ◽  
Hikaru Kozuma ◽  
Taral Patel ◽  
Ping Jiang ◽  
...  
Keyword(s):  
Gene Expression ◽  
Epithelial Cells ◽  
Intestinal Epithelial Cells ◽  
Intestinal Epithelial ◽  
Trefoil Factor ◽  
Intestinal Trefoil Factor ◽  
Factor Gene

scholarly journals Recombinant Adenovirus-Mediated Intestinal Trefoil Factor Gene Therapy for Burn-Induced Intestinal Mucosal Injury

PLoS ONE ◽  
2013 ◽  
Vol 8 (4) ◽  
pp. e62429 ◽  
Author(s):  
Yong Sun ◽  
Yun Zhu ◽  
Liangxi Wang ◽  
Xuefei Mao ◽  
Xi Peng ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Recombinant Adenovirus ◽  
Mucosal Injury ◽  
Trefoil Factor ◽  
Intestinal Trefoil Factor ◽  
Factor Gene ◽  
Intestinal Mucosal Injury

scholarly journals Molecular Cloning of the Rat Intestinal Trefoil Factor Gene

1995 ◽  
Vol 270 (16) ◽  
pp. 9353-9361 ◽  
Author(s):  
Bruce E. Sands ◽  
Haruhiko Ogata ◽  
Kathryn Lynch-Devaney ◽  
Michelle deBeaumont ◽  
Robert M. Ezzell ◽  
...  
Keyword(s):  
Molecular Cloning ◽  
Trefoil Factor ◽  
Intestinal Trefoil Factor ◽  
Factor Gene

scholarly journals Molecular cloning of mouse intestinal trefoil factor and its expression during goblet cell changes

1995 ◽  
Vol 311 (1) ◽  
pp. 293-297 ◽  
Author(s):  
M Tomita ◽  
H Itoh ◽  
N Ishikawa ◽  
A Higa ◽  
H Ide ◽  
...  
Keyword(s):  
Goblet Cell ◽  
Goblet Cells ◽  
Recovery Phase ◽  
Nippostrongylus Brasiliensis ◽  
Trefoil Factor ◽  
Intestinal Trefoil Factor ◽  
Cell Hyperplasia ◽  
Reverse Transcription Pcr ◽  
Rapid Amplification ◽  
Mitf Expression

A cDNA encoding mouse intestinal trefoil factor (mITF) was successfully cloned and sequenced from the small intestine of C57BL/6 mouse by using the combination of reverse transcription-PCR and rapid amplification of cDNA ends methods. The gene was, similar to rat and human ITFs, mainly expressed in the small and large intestine. The mITF expression was up-regulated during the recovery phase after depletion of goblet cells in acetic acid-induced colitis. On the other hand, the expression in the jejunum was not altered, while goblet cell hyperplasia was induced by Nippostrongylus brasiliensis infection. These results suggest that the mITF expression did not simply correlate with the number of goblet cells. The mITF may play an important role in the maintenance and repair of mucosal function of the rectum. Additionally, the mITF in the jejunum may play a role in alteration of the physicochemical nature of goblet cell mucins, thereby affecting the establishment of intestinal helminths.

scholarly journals Selective reduction of intestinal trefoil factor in untreated coeliac disease

2002 ◽  
Vol 130 (3) ◽  
pp. 526-531 ◽  
Author(s):  
C. CIACCI ◽  
D. DI VIZIO ◽  
R. SETH ◽  
G. INSABATO ◽  
G. MAZZACCA ◽  
...  
Keyword(s):  
Coeliac Disease ◽  
Selective Reduction ◽  
Trefoil Factor ◽  
Intestinal Trefoil Factor
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