PEGylation of superparamagnetic iron oxide nanoparticle for drug delivery applications with decreased toxicity: an in vivo study

2015 ◽  
Vol 17 (10) ◽  
Author(s):  
Suma Prabhu ◽  
Srinivas Mutalik ◽  
Sharada Rai ◽  
Nayanabhirama Udupa ◽  
Bola Sadashiva Satish Rao
2008 ◽  
Vol 47-50 ◽  
pp. 1097-1100 ◽  
Author(s):  
Shi Yuan Liu ◽  
Yu Han ◽  
Long Ping Yin ◽  
Ling Long ◽  
Rui Liu

Objectives: This report presents toxicological profile available on a superparamagnetic iron oxide (SPIO) nanoparticle in vivo.


Nanoscale ◽  
2019 ◽  
Vol 11 (27) ◽  
pp. 12905-12914 ◽  
Author(s):  
Manman Xie ◽  
Shijia Liu ◽  
Christopher J. Butch ◽  
Shaowei Liu ◽  
Ziyang Wang ◽  
...  

Superparamagnetic iron oxide nanoparticles (SPIONs) have a history of clinical use as contrast agents in T2 weighted MRI, though relatively low T2 relaxivity has caused them to fall out of favor as new faster MRI techniques have gained prominence.


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