Effects of Neuropeptide Y on the Functional State of the Afferent Inputs from the Arcuate Nucleus to the Suprachiasmatic Nucleus in Rats in Vitro

2018 ◽  
Vol 48 (4) ◽  
pp. 511-520
Author(s):  
A. N. Inyushkin ◽  
A. A. Petrova ◽  
M. A. Tkacheva
Keyword(s):  
Neuropeptide Y ◽  
Suprachiasmatic Nucleus ◽  
Functional State ◽  
Arcuate Nucleus ◽  
Afferent Inputs

Neuropeptide Y and glutamate block each other's phase shifts in the suprachiasmatic nucleus in vitro

Neuroscience ◽  
1997 ◽  
Vol 77 (4) ◽  
pp. 1049-1057 ◽  
Author(s):  
S.M Biello ◽  
D.A Golombek ◽  
M.E Harrington
Keyword(s):  
Neuropeptide Y ◽  
Suprachiasmatic Nucleus ◽  
Phase Shifts

Dexamethasone rapidly increases hypothalamic neuropeptide Y secretion in adrenalectomized ob/ob mice

1996 ◽  
Vol 271 (1) ◽  
pp. E151-E158 ◽  
Author(s):  
H. L. Chen ◽  
D. R. Romsos
Keyword(s):  
Neuropeptide Y ◽  
Arcuate Nucleus ◽  
Rapid Onset ◽  
Brown Adipose ◽  
Specific Enhancement ◽  
Brown Adipose Tissue Thermogenesis ◽  
The Central Nervous System ◽  
Rapid Transport ◽  
The Brain

A single intracerebroventricular injection of dexamethasone (DEX) rapidly (within 30 min) suppresses brown adipose tissue thermogenesis and increases plasma insulin concentrations in adrenal-ectomized (ADX) ob/ob mice but not in ADX lean mice. Intracerebroventricular neuropeptide Y (NPY) administered intracerebroventricularly causes these same metabolic changes within 30 min in both ob/ob and lean ADX mice. We therefore hypothesized that DEX exerts these rapid-onset metabolic actions in ob/ob mice via a phenotype-specific enhancement of NPY secretion within the central nervous system. In support of this hypothesis, DEX (a type II glucocorticoid receptor agonist) administered intracerebroventricularly selectively lowered NPY concentrations in the whole hypothalamus of ADX ob/ob mice by 35% and in the arcuate nucleus region by approximately 70% within 30 min but not in the brain stem or hippocampus or in any of these regions of lean mice. DEX also functioned in vitro to enhance depolarization-dependent release of NPY from hypothalamic blocks of ADX ob/ob mice but not of ADX lean mice. Thus DEX acts in the hypothalamus of ob/ob mice in a phenotype-specific manner to evoke rapid transport of NPY from cell bodies within the arcuate nucleus to terminal regions including the dorsomedial and ventromedial hypothalamic regions for release.

Effects of Neuropeptide Y on Neuron Spike Activity in the Rat Suprachiasmatic Nucleus in Vitro

2017 ◽  
Vol 47 (3) ◽  
pp. 337-344
Author(s):  
A. N. Inyushkin ◽  
A. A. Petrova ◽  
M. A. Tkacheva ◽  
E. M. Inyushkina
Keyword(s):  
Neuropeptide Y ◽  
Suprachiasmatic Nucleus ◽  
Spike Activity ◽  
Neuron Spike ◽  
Neuron Spike Activity

Responses to neuropeptide Y in adult hamster suprachiasmatic nucleus neurones in vitro

1998 ◽  
Vol 345 (2) ◽  
pp. 155-162 ◽  
Author(s):  
David J. Cutler ◽  
Hugh D. Piggins ◽  
Lisa A. Selbie ◽  
Rob Mason
Keyword(s):  
Neuropeptide Y ◽  
Suprachiasmatic Nucleus ◽  
Adult Hamster

Neuropeptide Y and Vasopressin Effects on Rat Suprachiasmatic Nucleus Neurons In Vitro

1988 ◽  
Vol 3 (3) ◽  
pp. 265-276 ◽  
Author(s):  
Shigenobu Shibata ◽  
Robert Y. Moore
Keyword(s):  
Neuropeptide Y ◽  
Suprachiasmatic Nucleus
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