Potentially inappropriate medications in Chinese community-dwelling older adults

2020 ◽  
Vol 42 (2) ◽  
pp. 598-603 ◽  
Author(s):  
Yamin Huang ◽  
Lu Zhang ◽  
Xingxing Huang ◽  
Keke Liu ◽  
Yangyong Yu ◽  
...  
Author(s):  
Priscila Horta Novaes ◽  
Danielle Teles da Cruz ◽  
Alessandra Lamas Granero Lucchetti ◽  
Isabel Cristina Gonçalves Leite ◽  
Giancarlo Lucchetti

2017 ◽  
Vol 73 (5) ◽  
pp. 615-621 ◽  
Author(s):  
Mariana Martins Gonzaga do Nascimento ◽  
Juliana Vaz de Melo Mambrini ◽  
Maria Fernanda Lima-Costa ◽  
Josélia Oliveira Araújo Firmo ◽  
Sérgio William Viana Peixoto ◽  
...  

2011 ◽  
Vol 26 (8) ◽  
pp. 606-615 ◽  
Author(s):  
Denys T. Lau ◽  
Nathaniel D. Mercaldo ◽  
Joseph W. Shega ◽  
Alfred Rademaker ◽  
Sandra Weintraub

This study provides empirical evidence on whether polypharmacy and potentially inappropriate prescription medications (PIRx, as defined by the 2003 Beers criteria) increase the likelihood of functional decline among community-dwelling older adults with dementia. Data were from the National Alzheimer’s Coordinating Center, Uniform Data Set (9/2005-9/2009). Study sample included 1994 community-dwelling participants aged ≥65 with dementia at baseline. Results showed that participants having ≥5 medications were more likely to have functional decline than participants having <5 medications. However, the increased likelihood was only apparent in participants who did not have PIRx. Instead of magnifying the associated risk as hypothesized, PIRx appeared to have a protective effect albeit marginally statistically significant. Therefore, increased medication burden may be associated with functional decline in community-dwelling older adults with dementia who are not prescribed with PIRx. More research is needed to understand which classes of medications have the most deleterious effect on this population.


BMJ Open ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. e041578
Author(s):  
Linglin Kong ◽  
Huimin Zhao ◽  
Junyao Fan ◽  
Quan Wang ◽  
Jie Li ◽  
...  

ObjectivesTo assess the prevalence of frailty and identify predictors of frailty among Chinese community-dwelling older adults with type 2 diabetes.DesignA cross-sectional design.SettingTwo community health centres in central China.Participants291 community-dwelling older adults aged ≥65 years with type 2 diabetes.Main outcome measuresData were collected via face-to-face interviews, anthropometric measurements, laboratory tests and community health files. The main outcome measure was frailty, as assessed by the frailty phenotype criteria. The multivariate logistic regression model was used to identify the predictors of frailty.ResultsThe prevalence of prefrailty and frailty were 51.5% and 19.2%, respectively. The significant predictors of frailty included alcohol drinking (ex-drinker) (OR 4.461, 95% CI 1.079 to 18.438), glycated haemoglobin (OR 1.434, 95% CI 1.045 to 1.968), nutritional status (malnutrition risk/malnutrition) (OR 8.062, 95% CI 2.470 to 26.317), depressive symptoms (OR 1.438, 95% CI 1.166 to 1.773) and exercise behaviour (OR 0.796, 95% CI 0.716 to 0.884).ConclusionsA high prevalence of frailty was found among older adults with type 2 diabetes in the Chinese community. Frailty identification and multifaceted interventions should be developed for this population, taking into consideration proper glycaemic control, nutritional instruction, depressive symptoms improvement and enhancement of self-care behaviours.


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